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1 Possible Causes for WP760

  • Anthracycline

    Moreover, WP760 caused nucleolar stress and led to activation of the p53 pathway.[ncbi.nlm.nih.gov] WP760 did not induce double-stranded DNA breaks but strongly inhibited global transcription.[ncbi.nlm.nih.gov] Furthermore, WP760 downregulated IGF1R and upregulated PLK2 expression in most of the tested melanoma cell lines.[ncbi.nlm.nih.gov]

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