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171 Possible Causes for XRCC3

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  • Troglitazone

    LIG1, BRCA1, TOP2A, POLE2, RAD54L, GTSE1, POLE, PCNA, RAD51, MDC1, UIP1, RAD51AP1, HMGB2, RPA1, TYMS, POLQ, NEIL3, CCNA2, CHAF1A, PTTG1, MAP2K6, RFC5, FANCG, RPA3, FANCB, XRCC3[wjgnet.com] , H2AFX, TOPBP1, RECQL4, BLM, RAD51C, POLD1, FANCD2, APEX2, FEN1DNA recombination113.91E-06CHEK1, LIG1, XRCC3, H2AFX, RPA1, BLM, RAD51C, RAD54L, RAD51, RAD51AP1, EXO1Protein[wjgnet.com] UHRF1, EXO1, CHEK1, LIG1, BRCA1, TOP2A, POLE2, RAD54L, POLE, PCNA, RAD51, MDC1, UIP1, RAD51AP1, HMGB2, RPA1, TYMS, POLQ, NEIL3, CHAF1A, PTTG1, RFC5, FANCG, RPA3, FANCB, XRCC3[wjgnet.com]

  • Gastrointestinal Stromal Tumor

    ., XRCC3, Rad51, etc.).[ncbi.nlm.nih.gov]

  • Benzene Poisoning

    We found that no individuals had the XRCC2 codon 188 variant alleles or Met/Met genotype of XRCC3 codon 241 in this study population.[ncbi.nlm.nih.gov] Genetic Polymorphisms in XRCC1, APE1, ADPRT, XRCC2 and XRCC3 and Risk of Chronic Benzene Poisoning in a Chinese Occupational Population.[journals.plos.org] We genotyped single-nucleotide polymorphisms at codons 194, 280, and 399 of XRCC1, codon 148 of APE1, codon 762 of ADPRT, codon 188 of XRCC2, and codon 241 of XRCC3 in 152[ncbi.nlm.nih.gov]

  • Obsessive-Compulsive Disorder

    Genotyping of XRCC1, XRCC3, XPD, XPG, APE1 and HOGG1 was performed by polymerase chain reactionrestriction fragment length polymorphism.[ncbi.nlm.nih.gov]

  • Diffuse Gastric Cancer

    METHODS: ERCC1 118 T/C, XRCC1 399 G/A, XPD 312 G/A, XPD 751 A/C, XRCC3 241 C/T, MS 919 A/G, GSTP1 105 A/G, GSTM1-null/positive and GSTT1-null/positive genotypes were obtained[ncbi.nlm.nih.gov] There was no significant difference between cases and controls for XPD 751 A/C, ERCC1 118 T/C, XRCC3 241 C/T, XRCC1 399 G/A, XPD 312 G/A, GSTM1-null/positive and MS 919 A[ncbi.nlm.nih.gov]

  • Osteosarcoma

    We identified 12 SNVs in CTLA-4, IL-8, MDM2, PRCKG, RECQL5, TNF-a, TP53, XRCC3, and VEGF that correlated with osteosarcoma susceptibility.[ncbi.nlm.nih.gov] These included CTLA-4 rs231775, CTLA-4 rs5742909, PRCKG rs454006, RECQL5 rs820196, TNF-α rs1800629, TP53 rs1042522, XRCC3 rs861539, VEGF rs699947, and VEGF rs3025039.[ncbi.nlm.nih.gov]

  • Xeroderma Pigmentosum Complementation Group B

    (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3): XRCC3 antibodies XRCC3 Proteins BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1): BRIP1 antibodies[antibodies-online.com] Cerevisiae)): RAD51C antibodies RAD51C Proteins XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2): XRCC2 antibodies XRCC2 ELISA Kits XRCC2 Proteins XRCC3[antibodies-online.com]

  • Myelodysplasia

    The XRCC3 protein also functions in the double-strand break repair pathway and directly interacts with and stabilizes RAD51.[haematologica.org] A polymorphism at codon 241 in the XRCC3 gene results in a Thr-to-Met amino acid substitution and this variant allele has been associated with higher levels of DNA adducts[haematologica.org] […] age, translating in a 2.66-fold increased risk of t-AML. 27 The risk of the development of AML was found to be significantly increased when both variant RAD51 -135C and XRCC3[haematologica.org]

  • Progressive External Ophthalmoplegia - Myopathy - Emaciation Syndrome

    Breast Carcinoma ABL1 ATM BARD1 BRCA1 BRCA2 BRIP1 CHEK1 CHEK2 EMSY EXO1 FOXM1 FTO H2AFX HSPA1B PALB2 PARP1 RAD51 RAD51B RAD51C RAD54L RECQL SIRT1 XRCC2 XRCC3 Prostatic Neoplasms[selfdecode.com] BRCA2 CHEK2 ERCC2 GADD45A HSPA1A MLH1 MSH3 NBN OGG1 PARP1 PRKDC RAD23B SIRT1 XRCC1 Stomach Neoplasms APEX1 ATM CHEK2 DDB1 ERCC1 ERCC2 GADD45A MUTYH NPM1 PRPF19 RAD23A XRCC1 XRCC3[selfdecode.com] FANCD2 FANCF FANCG FANCL FANCM RAD51C SLX4 Colorectal Cancer CHEK2 ERCC2 EXO1 EYA4 FEN1 MLH1 MSH2 POLD1 POLD3 POLE UNG Melanoma APEX1 ASF1A ATM CDK2 ERCC1 FTO HSPA1A RPS3 XRCC3[selfdecode.com]

  • Temozolomide

    17 119 Reference GG/GA 12 38 2.32 0.95-5.62 MGMT (rs2308327) AA 17 120 Reference GG/GA 12 37 2.40 0.99-5.84 MGMT (rs12917) CC 24 126 Reference TT/TC 5 31 0.84 0.28-2.55 XRCC3[academic.oup.com] GG 16 44 0.28 0.10-0.75 Abbreviations: OR, odds ratio; CI, confidence interval; NQO1, NAD(P)H dehydrogenase, quinone 1; MGMT, O 6 - methylguanine-DNA methyltransferase; XRCC3[academic.oup.com]

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