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123 Possible Causes for Abdominal Cramps, Loss of Appetite, Tryptophan Increased

  • Pellagra

    Investigation of urinary tryptophan metabolites following an oral tryptophan load, showed increased excretion of kynurenine and kynurenic acid but reduced excretion of 3-hydroxy-kynurenine[ncbi.nlm.nih.gov] Symptoms Of Pellagra Include: Abdominal cramps Delusional thoughts Severe depression Diarrhea Cognitive problems Headaches Appetite loss Severe fatigue Persistent nausea that[epainassist.com] Symptoms of pellagra include: Delusions or mental confusion Diarrhea Weakness Loss of appetite Pain in abdomen Inflamed mucous membrane Scaly skin sores, especially in sun-exposed[nlm.nih.gov]

  • Abdominal Migraine

    If you intake adequate L-tryptophan foods initially to increase blood levels of tryptophan, followed shortly by a carbohydrate snack, it is postulated that you can then increase[ndnr.com] The pain is either along the midline or unspecified and is frequently accompanied by abdominal tenderness, cramp-like spasms, bloating, vomiting, and loss of appetite.[streetdirectory.com] At least two of the following four associated symptoms or signs: Anorexia (loss of appetite) Nausea Vomiting Pallor Pain can be severe enough to interfere with normal activities[migraine.newlifeoutlook.com]

  • Acute Hepatic Porphyria

    These findings suggest that increased tryptophan and 5-hydroxytryptamine in the nervous system may be responsible for the neurologic dysfunctions observed in humans with acute[science.sciencemag.org] Most important symptoms are related to the gastrointestinal tract and include intense and nonspecific abdominal pain that may be cramping, constipation, nausea, vomiting,[symptoma.com] Decreased activity of the heme-dependent protein tryptophan pyrrolase in the liver supposedly increases central and systemic tryptophan levels due to decreased tryptophan[emedicine.medscape.com]

  • Acute Intermittent Porphyria

    […] is an imbalance in the kynurenine metabolic pathway in AIP patients, with an increase of the kynurenine/tryptophan ratio in urine and a reduction of the kynurenic acid/kynurenine[ncbi.nlm.nih.gov] She had no skin manifestations regardless of sun exposure and her family history was not significant; there were three previous episodes of atypical abdominal cramps due to[cyberleninka.org] Symptomatic treatment of nausea and loss of appetite is important to help ensure an adequate diet.[doi.org]

  • Cushing Ulcer

    3 Gastrin Stomach distention/alkalinization/amino acids/peptides/vagus Upregulated by 5 Gastrin Stomach pH Downregulated by 1 Gastrin Increased by ZE/PPI/phenylalanine/tryptophan[memorize.com] This type of stress ulcer is manifested by loss of appetite, weakness, nausea and epigastric pain, which worsens at night.[healmytrauma.info] Those symptoms may include a burning pain that comes and goes, loss of appetite, blood in the stool and vomiting of blood.[healthyliving.azcentral.com]

  • Malignant Carcinoid Syndrome

    Increased metabolism of tryptophan by the tumor has been linked to symptoms in patients with carcinoid. [16] The main clinical characteristics of the carcinoids arising in[emedicine.medscape.com] Carcinoid syndrome develops in some people with carcinoid tumors and is characterized by cutaneous flushing, abdominal cramps, and diarrhea.[msdmanuals.com] High acid levels can lead to irritation of the lining of the stomach and even stomach ulcers, which can cause pain, nausea, and loss of appetite.[cancer.org]

  • Hookworm Infection

    Increasing concentrations of hematin were added and incubated for 3 min prior to measurement. Animal vaccine trials.[iai.asm.org] A person with a heavy infection may experience abdominal pain, diarrhea, loss of appetite, weight loss, fatigue and anemia.[web.archive.org] At first, people may have an itchy rash where the larvae penetrate the skin, then fever, coughing, and wheezing or abdominal pain, loss of appetite, and diarrhea.[msdmanuals.com]

  • Chronic Fatigue Syndrome

    IL-1β also increases brain tryptophan concentrations and the rate of 5- hydroxytryptamine (5-HT) metabolism, which may further activate the HPA axis [ 154 ].[doi.org] Digestive disturbances – These include; nausea, loss of appetite, indigestion, excessive wind, bloating, abdominal cramps, alternating diarrhea and constipation.[hacw.nhs.uk] Signs and symptoms of severe infection include: Watery diarrhea 10 to 15 times a day Abdominal cramping and pain, which may be severe Rapid heart rate Fever Blood or pus in[mayoclinic.org]

  • Irritable Bowel Syndrome

    Yunshuang Yue, Yuming Guo and Ying Yang, Effects of dietary l-tryptophan supplementation on intestinal response to chronic unpredictable stress in broilers, Amino Acids, 49[doi.org] Abdominal cramping/pain was more common in women (12–55%) than in men (7–38%).[doi.org] Nausea Dizziness Loss of appetite In children, symptoms are variable and are age dependent.[stanfordchildrens.org]

  • Zinc Deficiency

    Simultaneously, pro-inflammatory cytokines increase the enzyme IDO resulting in increased turnover of tryptophan to quinolinic acid, a NMDA receptor agonist.[doi.org] Initially, you would experience gastrointestinal problems, such as an upset stomach, abdominal cramps and vomiting.[study.com] Loss of appetite and/or anorexia : A deficiency of zinc causes decreased loss of appetite.[newsmax.com]

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