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6 Possible Causes for Abdominal CT Scan showing Splenic Enlargement

  • Hodgkin's Disease

    The aetiology of multiple sclerosis (MS) is still an unresolved question. Several recently reported studies are implicating Epstein-Barr virus (EBV) as one of the key players in MS pathogenesis. We present a 21-year-old male patient with a history of EBV-related infectious mononucleosis in puberty and Hodgkin's[…][]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Philadelphia chromosome–positive chronic myeloid leukemia (Ph CML) is a myeloproliferative disorder in which early progenitor cells undergo malignant transformation. The pathogenesis of this disease is attributed to the presence of the Philadelphia chromosome, which is the result of a reciprocal translocation between[…][]

  • Chronic Eosinophilic Leukemia

    Homepage Rare diseases Search Search for a rare disease Chronic eosinophilic leukemia ORPHA:168940 Synonym(s): - Prevalence: - Inheritance: - Age of onset: Childhood, Adolescent, Adult ICD-10: D47.5 OMIM: - UMLS: C0346421 MeSH: - GARD: - MedDRA: 10065854 Summary An Orphanet summary for this disease is currently[…][]

  • Splenic Rupture

    A CT scan showed a massive intra-abdominal and pelvic free fluid consistent with blood. The spleen was enlarged and fluid noted around the liver.[] On hospital day two, the patient developed nausea and abdominal pain with associated hypotension.[] At laparotomy, a grade III splenic laceration at the hilum was identified and a splenectomy performed. The patient recovered completely.[]

  • Erdheim-Chester Disease

    For Patient 2, the scan demonstrated mild splenic enlargement (15 cm).[] The films showed bone resorption and some features suggesting the possibility of Paget’s disease. Abdominal CT scans were available for three patients.[] Abdominal CTs in Patients 3 and 5 showed perinephric retroperitoneal fibrosis, which resulted in bilateral hydronephrosis.[]

  • Hepatic Vein Thrombosis

    An abdominal CT scan showed an enlarged spleen and a thrombus in the splenic vein extending into the portal trunk.[]

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