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139 Possible Causes for Abdominal Mass, Irinotecan, Peripheral Neuropathy

  • Adenocarcinoma of the Colon

    Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal .N Engl J Med 2004;351:337-45. 13. T. Delaunoit1, S.R. Alberts, D.J.[scielo.mec.pt] mass Strep. bovis endocarditis systemic symptoms (malaise, fatigue, weight loss ) Physical exam palpable mass on rectal exam (if large enough) Evaluation Barium enema X-ray[medbullets.com] Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov]

  • Pancreatic Adenocarcinoma

    Options for front-line therapy include both infusional 5-fluorouracil, leucovorin, irinotecan, oxaliplatin (FOLFIRINOX) and the combination of gemcitabine plus nab-paclitaxel[ncbi.nlm.nih.gov] However, when she was admitted to our hospital 13 years later for an annual follow-up, abdominal CT revealed a mass in the dilated remnant of her lower bile duct.[ncbi.nlm.nih.gov] The main adverse effects are peripheral neuropathy, neutropenia, thrombocytopenia and fatigue.[nature.com]

  • Malignant Gastric Neoplasm

    Irinotecan versus non‐irinotecan‐containing regimens for advanced gastric cancer Irinotecan versus non‐irinotecan‐containing regimens for advanced gastric cancer Patient or[doi.org] In early stages it presents with non-specific and vague symptoms, in advanced stages it may cause nausea and vomiting, dysphagia, loss of appetite, abdominal mass or weight[orpha.net] Side effects may include: tiredness nausea and vomiting nerve damage ( peripheral neuropathy ) hair loss diarrhoea anaemia (a lack of red blood cells) weight loss skin changes[nhs.uk]

  • Cecal Adenocarcinoma

    Irinotecan 24,25 Days 1 and 8: Irinotecan 125mg/m 2 IV over 30–90 minutes. Repeat cycle every 3 weeks. OR Day 1: Irinotecan 300–350mg/m 2 IV over 30–90 minutes.[cancertherapyadvisor.com] A 41-year-old male patient was admitted because of a palpable abdominal mass.[kjim.org] Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov]

  • Adenocarcinoma of the Ovary

    The 50% growth inhibitory concentrations (IC50) (nM) of various anticancer drugs were: cisplatin 10,000, paclitaxel 80, SN-38 (irinotecan metabolite) 460, and gemcitabine[ncbi.nlm.nih.gov] On physical examination, a large abdominal mass was palpable predominantly on left side extending above the umbilical region.[ccij-online.org] Combination chemotherapy with irinotecan hydrochloride plus cisplatin has been reported to be effective for primary and recurrent or resistant CCC.[ncbi.nlm.nih.gov]

  • Gastric Adenocarcinoma

    ., 5-FU (5 μ M); cisplatin (0.5 μ M); irinotecan (2.5 μ M); carboplatin (5 μ M); paclitaxel (2-4 n M); and X rays (1.8 Gy)] also potentiated gastric cancer clonogenic cell[ncbi.nlm.nih.gov] Here, we present a 45-year-old male complaining of a lymph node mass in the neck, without any abdominal symptoms, diagnosed as HL and gastric adenocarcinoma with hepatitis[ncbi.nlm.nih.gov] neuropathy grade 2 Inability to tolerate intravenous hydration e.g due to cardiac disease Co-morbidities (based on clinical judgement by the investigator) that in the view[clinicaltrials.gov]

  • Metastatic Ovarian Carcinoma

    Research output : Article 2000 Irinotecan--második vonalbeli kezeléssel szerzett tapasztalatok elórehaladott colorectalis daganatokban.[hungary.pure.elsevier.com] mass / pain / rectal bleeding / jaundice Diagnosis Final diagnosis by histology and immunohistochemistry Treatment Debulking surgery with or without chemotherapy Clinical[pathologyoutlines.com] A specific chemotherapy regimen for rare clear-cell cancers is also under investigation: irinotecan combined with cisplatin. [62] PARP inhibitors have also shown promise in[en.wikipedia.org]

  • Malignant Neoplasm of Pancreas

    If you’re in fairly good health you may receive FOLFIRINOX (5-FU/ leucovorin / oxaliplatin / irinotecan ).[webmd.com] They may also present as palpable abdominal masses. Serous cystadenomas are almost always benign, and surgical resection is curative in the vast majority of patients.[pancreaticcancer.net.au] […] may occur in either the central nervous system (CNS) or the peripheral nervous system (PNS).[en.wikipedia.org]

  • Colon Carcinoma

    Irinotecan 24,25 Days 1 and 8: Irinotecan 125mg/m 2 IV over 30–90 minutes. Repeat cycle every 3 weeks. OR Day 1: Irinotecan 300–350mg/m 2 IV over 30–90 minutes.[cancertherapyadvisor.com] Pregnant women with suspicious abdominal mass should be evaluated for a possible colorectal carcinoma even in the absence of any other gastrointestinal symptoms associated[ncbi.nlm.nih.gov] Side effects include fatigue, nausea, increased risk of infection, anemia, and peripheral neuropathy (tingling or numbness of the fingers and toes).[emedicinehealth.com]

  • Peritoneal Metastasis

    Twenty patients received oxaliplatin-based (OX) and twelve patients received irinotecan-based HIPEC (IRI).[ncbi.nlm.nih.gov] The abdominal mass was 26 x 17 x 12 cm in size, as determined by magnetic resonance imaging, and was diagnosed as a peritoneal relapse of GIST.[ncbi.nlm.nih.gov] Leukopenia, fatigue and peripheral neuropathy were higher on the triplet regimen than the doublet regimens.[ncbi.nlm.nih.gov]

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