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3,805 Possible Causes for Abdominal Pain, Bone Pain, Fatigue, Lactate Dehydrogenase Increased

  • T-Cell Lymphoma

    Diagnosis of lymphoma has to be suspected when patients have systemic manifestations including fever, fatigue, abdominal pain, EBV-associated liver disease, et al., and uveitis[ncbi.nlm.nih.gov] A high calcium level in the blood (hypercalcaemia) may also be present which can cause confusion, bone pain and severe constipation.[leukaemia.org.au] Ten days later while in rehabilitation, he started complaining of progressive fatigue and altered mental status was noted.[ncbi.nlm.nih.gov] Because a bone marrow biopsy may be painful, a mild, calming (sedative) medication may be offered before the procedure is conducted.[rarediseases.org]

  • Familial Myelofibrosis

    Anemia is one of the hallmarks of pancytopenia and is associated with fatigue, pallor, and cyanosis. Children may also be tachypneic due to hypoxia.[symptoma.com] Children may complain about abdominal pain. Developmental delays have been reported.[symptoma.com] Lack of red blood cells manifests in fatigue, pallor, and cyanosis, while white blood cell deficiencies result in an increased susceptibility to infection.[symptoma.com] Because of extramedullary hematopoiesis, myelofibrosis is usually associated with enlarged liver and spleen, which may cause abdominal pain, nausea, loss of appetite and weight[symptoma.com]

  • Primary Myelofibrosis

    The latter was associated more frequently with anaemia, thrombocytopenia, peripheral blood blasts and increased lactate dehydrogenase levels.[ncbi.nlm.nih.gov] The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Hepatosplenomegaly may cause upper abdominal pain, portal hypertension and ascites.[symptoma.com] Involved field radiotherapy is most useful for post-splenectomy hepatomegaly, non-hepatosplenic EMH, PMF-associated pulmonary hypertension and extremity bone pain. Am.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    […] numbers of eosinophils and basophils Differential WCC shows granulocytes at all stages of development Anaemia (normocytic/normochromic) Biochemistry: Lactate dehydrogenase[geekymedics.com] On initial presentation she reported fatigue, night sweats, and early satiety, and was found to have a white blood cell (WBC) count of 69.3 109 /L and platelet count of 366[ncbi.nlm.nih.gov] Approximately 5 months after the initiation of nilotinib for CML, he developed upper abdominal distension with intermitting abdominal pain, and based on abdominal computed[ncbi.nlm.nih.gov] They include: Weakness Fatigue Night sweats Weight loss Fever Bone pain (caused by leukemia cells spreading from the marrow cavity to the surface of the bone or into the joint[cancer.org]

  • Multiple Myeloma

    She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure.[ncbi.nlm.nih.gov] His abdominal pain became localized in the infraumbilical area and a small mass was palpated on the right lower quadrant on subsequent examination.[ncbi.nlm.nih.gov] Here we report a patient with MM presenting with renal failure, anemia, and bone pain. The renal biopsy showed DDD.[ncbi.nlm.nih.gov] The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).[orpha.net]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    The following are predictive of a shorter chronic phase: Increased splenomegaly. Older age. Male gender. Elevated serum lactate dehydrogenase.[cancer.gov] […] in the bones and joints Pain in the abdomen How is CML diagnosed?[symptoma.com] CML; hypertension (36%), pneumonia (9%), abdominal pain (8%), and rash (8%) in accelerated-phase CML patients; hypertension (26%), cardiac failure (11%), febrile neutropenia[ascopost.com] Gastrointestinal Toxicity: Diarrhea, nausea, vomiting, and abdominal pain can occur.[press.pfizer.com]

  • Acute Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[ncbi.nlm.nih.gov] We report a 28-year-old male with the B-cell ALL who presented with extensive osteolytic lesions, bone pain, hepatosplenomegaly, and pancytopenia without circulating blasts[ncbi.nlm.nih.gov] A 21-year-old woman who presented fatigue had a new diagnosis of acute lymphoblastic leukemia underwent FDG PET/CT.[ncbi.nlm.nih.gov] A 30-year-old pregnant woman presented at 16 weeks' gestation with epistaxis, jaundice, diffuse abdominal pain and distension, massive hepatosplenomegaly and peripheral oedema[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    […] infectious mononucleosis (IM), including issues of diagnosis, the determination of splenomegaly, and other measures of disease status, the relationship of the disease to chronic fatigue[ncbi.nlm.nih.gov] The evaluation of a febrile patient with acute abdominal pain represents a frequent yet possibly challenging situation in the emergency department (ED).[ncbi.nlm.nih.gov] She suddenly developed intermittent high fever and general fatigue with liver dysfunction, remarkable lymphocytosis and laboratory data suggestive of CMV reactivation.[ncbi.nlm.nih.gov] A few patients may develop prolonged fatigue for a few months or even years.[symptoma.com]

    Missing: Bone Pain
  • B-Precursor Acute Lymphoblastic Leukemia

    The symptoms caused by the early stages of the disease are not pathognomonic and include anorexia, fatigue, weight loss or a developmental arrest in younger children.[symptoma.com] The most common ( 2%) serious adverse reactions associated with BESPONSA were infection (23%), febrile neutropenia (11%), haemorrhage (5%), abdominal pain (3%), pyrexia (3%[pfizer.com] We present the case of a 9-year-old girl from northwestern Greece admitted to our Hospital because of malaise, low-grade fever, intermittent hip joint pain, anemia, leukopenia[ncbi.nlm.nih.gov] […] in the bones or stomach pain or a feeling of fullness below the ribs painless lumps in the neck, underarm, stomach, or groin tests that examine the blood and bone marrow[icd10data.com]

  • Acute Leukemia

    The initial manifestations of leukemia are generally signs of bone marrow failure, such as pallor, fatigue, fever, bleeding, and infection related to peripheral blood cytopenias[ncbi.nlm.nih.gov] Expert commentary: The diagnosis of typhlitis still relies on clinical and radiologic features consisting of fever, abdominal pain and thickness of a segment of the bowel[ncbi.nlm.nih.gov] Herein we present a standard risk pediatric acute lymphobiastic leukemia patient who developed myalgia, bone pain, bone marrow aplasia and sinusoidal obstruction syndrome[ncbi.nlm.nih.gov] […] and perceived fatigue [ 30 ].[journals.plos.org]

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