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12 Possible Causes for Abdominal Pain, Cholestatic Jaundice, Liver Biopsy showing Periportal Necrosis

  • Primary Sclerosing Cholangitis

    A 39-year-old man presented with diarrhea and abdominal pain.[ncbi.nlm.nih.gov] The post-operative course, complicated by cholestatic jaundice, and subsequent clinical complications are described, showing how the diagnosis of sclerosing cholangitis was[ncbi.nlm.nih.gov] He had suffered from repeated abdominal pain and cholangitis for 3 years.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] Severe cholestatic jaundice and right upper quadrant abdominal pain may occur in elderly patients.[doi.org] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Hepatitis A

    Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] In adults, most will present with jaundice that typically recovers completely by 8 weeks. Rarely, a prolonged cholestatic jaundice lasting about 10 weeks can be seen.[clinicaladvisor.com] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Hepatitis B

    Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease, gastroenterology Symptoms None, yellowish skin, tiredness, dark urine, abdominal pain Classification[en.wikipedia.org] After ten days of TDF administration, nausea, vomiting and abdominal pain developed.[ncbi.nlm.nih.gov] As symptoms of abdominal pain and jaundice were presented on the fifth day, he re-admitted. The patient expired because of hepatorenal and cardiac insufficiency.[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org] All other causes of cholestatic jaundice were ruled out.[ncbi.nlm.nih.gov]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org] Cholestatic hepatic dysfunction (clinically difficult to differentiate from obstructive jaundice) Phenothiazines (chlorpromazine): most common drug-induced cholestatic hepatitis[quizlet.com]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] At 45 years of age, the patient complained of bloody diarrhea and abdominal pain, and she was diagnosed with ulcerative colitis by colonoscopy and histological examination[ncbi.nlm.nih.gov] Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice. J Clin Invest. 1995 Jun. 95(6):2581-6. [Medline].[emedicine.medscape.com]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[jcdr.net] She denied fever, rash or abdominal pain.[nature.com] The laboratory findings were consistent with cholestatic jaundice. He had marked elevation of bilirubin and alkaline phosphatase.[ijem.in]

  • Isoniazid Hepatitis

    Seven patients initially experienced excess fatigue, nausea, or abdominal pain, but waited until the onset of jaundice before seeking medical attention.[cdc.gov] Cholestatic jaundice caused by ethambutol. Br Med J 1986; 292: 866.[livertox.nih.gov] These products have been associated with an initial cholestatic hepatitis followed by prolonged jaundice ( 66, 67, 68 ).[gi.org]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org] Jaundice develops in more severe cases.[emedicine.medscape.com]

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