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12 Possible Causes for Abdominal Pain, Globulins Increased, Liver Biopsy showing Periportal Necrosis

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Anti-HB antibodies were detected after gamma globulin therapy.[link.springer.com] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org]

  • Viral Hepatitis

    Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov] This case report, along with the review presented, describes a patient diagnosed with acute viral hepatitis, who developed a framework of intense abdominal pain and laboratorial[ncbi.nlm.nih.gov]

  • Hepatitis B

    Household Contact Living with someone who has chronic hepatitis B increases the risk of getting infected.[verywellhealth.com] Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease, gastroenterology Symptoms None, yellowish skin, tiredness, dark urine, abdominal pain Classification[en.wikipedia.org] After ten days of TDF administration, nausea, vomiting and abdominal pain developed.[ncbi.nlm.nih.gov]

  • Hepatitis A

    , which can help increase protection to HAV.[liverfoundation.org] Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] More than 80% of affected individuals have increased gamma globulin in the blood.[hepatitiscentral.com] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] […] in testosterone binding globulin levels may occur and total serum testosterone levels may overestimate free testosterone.[doi.org] At 45 years of age, the patient complained of bloody diarrhea and abdominal pain, and she was diagnosed with ulcerative colitis by colonoscopy and histological examination[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    Severe chronic active hepatitis, defined as the presence of a fivefold increase in serum aminotransferases and a twofold rise in gamma globulin for at least 10 weeks, is considered[ncbi.nlm.nih.gov] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Chills Clay-colored stools Darkened urine Fever Jaundice (yellowing of the skin and eyes) Nausea Pain below the shoulder blade Right upper quadrant or middle abdominal pain[verywellhealth.com]

  • Bacterial Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] pain WHO fact sheet of hepatitis Viral Hepatitis at the Centers for Disease Control[en.wikipedia.org] Summary Points New onset fever, abdominal pain, confusion, or other signs or symptoms of infection in a cirrhotic patient should prompt an evaluation of the ascitic fluid[hepatitisc.uw.edu]

  • Chronic Hepatitis

    One characteristic laboratory feature of AIH is elevation of serum globulins, in particular, gamma globulin, with a selective increase in IgG, which is generally 1.2-3.0 times[doi.org] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

  • Hepatitis D

    In multivariate analysis, lower albumin concentration (p 0.0001) and higher γ-globulin concentration (p 4 ).[gut.bmj.com] A comparison of the first and third liver-biopsy specimens showed a significant reduction of portal inflammation (P 0.05) in patients treated with the higher dose of interferon[nejm.org] pain Tiredness Loss of appetite Dark-colored urine Joint pain People with chronic hepatitis B — who then acquire hepatitis D — will usually develop chronic hepatitis D virus[chop.edu]

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