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11 Possible Causes for Abdominal Pain, Lactate Dehydrogenase Increased, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    Lactate dehydrogenase (LD) – an enzyme released with cell damage; found in cells throughout the body.[labtestsonline.org] Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org] However, on the seventh day, she complained of progressive abdominal pain, and showed hypotension and tachycardia.[casereports.in]

  • Aflatoxicosis

    increased India isolates of Aspergillus Jalgaon District lactate content Lactate dehydrogenase methanol method Mycoflora mycotoxins Nabney Nesbitt Number oil cakes oil samples[books.google.com] Patients will appear ill with fever, jaundice, nausea, vomiting, abdominal pain, and hemorrhagic diathesis, hepatomegaly, and elevated liver function tests.[visualdx.com] Aflatoxins can cause: Nausea, vomiting, and abdominal pain Convulsions Pulmonary edema, which is fluid buildup (edema) in the lungs ('pulmon-') Cerebral edema, which is fluid[study.com]

  • Isoniazid Hepatitis

    Seven patients initially experienced excess fatigue, nausea, or abdominal pain, but waited until the onset of jaundice before seeking medical attention.[cdc.gov] Only 6 patients (1.4%; 95% CI, 0.53.2) had symptoms of hepatitis, such as asthenia, nausea, or mild abdominal pain.[natap.org] Usually, the onset is abrupt, with chills, fever, rash, pruritus, arthralgia, headache, abdominal pain, anorexia, nausea and vomiting.[patient.info]

  • Hepatitis A

    Liver enzymes like aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transferase and lactate dehydrogenase were severely elevated.[ncbi.nlm.nih.gov] Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Chills Clay-colored stools Darkened urine Fever Jaundice (yellowing of the skin and eyes) Nausea Pain below the shoulder blade Right upper quadrant or middle abdominal pain[verywellhealth.com] Intermittent fever accompanied by chills, right upper quadrant abdominal pain, and jaundice have been established as Charcot's triad.[patient.info]

  • Autoimmune Hepatitis

    Lactate dehydrogenase (LD) – an enzyme released with cell damage; found in cells throughout the body.[labtestsonline.org] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org]

  • Chronic Hepatitis

    Lactate dehydrogenase (LD) – an enzyme released with cell damage; found in cells throughout the body.[labtestsonline.org] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

  • Iron Poisoning

    Hepatotoxicity is manifested by elevated serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and bilirubin.[healio.com] Liver biopsy in a patient with hepatotoxicity will show hepatocellular necrosis in the periportal hepatocytes (Zone 1).[meducator3.net] Scarring in either organ can cause crampy abdominal pain and vomiting. Severe scarring of the liver ( cirrhosis ) can develop later.[merckmanuals.com]

  • Bacterial Hepatitis

    […] risk of spontaneous bacterial peritonitis. [ 11 ] Elevated total protein, low glucose concentration, and elevated lactate dehydrogenase ascitic values are seen in the setting[hepatitisc.uw.edu] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] pain WHO fact sheet of hepatitis Viral Hepatitis at the Centers for Disease Control[en.wikipedia.org]

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