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12 Possible Causes for Abdominal Pain, Liver Biopsy showing Hepatocyte Necrosis, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    It usually shows focal, sometimes extensive, hemorrhagic or coagulative necrosis of the hepatocytes with limited infammatory response (Figure 2).[doi.org] Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org] However, on the seventh day, she complained of progressive abdominal pain, and showed hypotension and tachycardia.[casereports.in]

  • Hepatitis B

    Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease, gastroenterology Symptoms None, yellowish skin, tiredness, dark urine, abdominal pain Classification[en.wikipedia.org] After ten days of TDF administration, nausea, vomiting and abdominal pain developed.[ncbi.nlm.nih.gov] As symptoms of abdominal pain and jaundice were presented on the fifth day, he re-admitted. The patient expired because of hepatorenal and cardiac insufficiency.[ncbi.nlm.nih.gov]

  • Hepatitis A

    Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov] One week later patient's condition worsened, she was jaundiced, with persistent vomiting and looked acutely ill and uncomfortable with severe steady abdominal pain mainly[ncbi.nlm.nih.gov]

  • Aflatoxicosis

    Patients will appear ill with fever, jaundice, nausea, vomiting, abdominal pain, and hemorrhagic diathesis, hepatomegaly, and elevated liver function tests.[visualdx.com] Aflatoxins can cause: Nausea, vomiting, and abdominal pain Convulsions Pulmonary edema, which is fluid buildup (edema) in the lungs ('pulmon-') Cerebral edema, which is fluid[study.com]

  • Chronic Active Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Chills Clay-colored stools Darkened urine Fever Jaundice (yellowing of the skin and eyes) Nausea Pain below the shoulder blade Right upper quadrant or middle abdominal pain[verywellhealth.com] Intermittent fever accompanied by chills, right upper quadrant abdominal pain, and jaundice have been established as Charcot's triad.[patient.info]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Liver biopsies in such cases show features of both PBC (granulomatous inflammation and bile duct lesions) and AIH (piecemeal necrosis and spotty hepatocyte necrosis) ( Figure[dx.doi.org] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org]

  • Iron Poisoning

    Liver biopsy in a patient with hepatotoxicity will show hepatocellular necrosis in the periportal hepatocytes (Zone 1).[meducator3.net] Scarring in either organ can cause crampy abdominal pain and vomiting. Severe scarring of the liver ( cirrhosis ) can develop later.[merckmanuals.com] Of note, adults suffering from IP may not report vomitus and abdominal pain.[symptoma.com]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Liver biopsy normally shows ballooning degeneration, focal hepatocyte necrosis, and neutrophilic infiltration[ 4, 20 ].[doi.org] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[jcdr.net] He underwent transjugular liver biopsy which showed mixed cholestatic and hepatocellular injury pattern with acute hepatitis, hepatocyte necrosis, extensive intrahepatic and[karger.com] She denied fever, rash or abdominal pain.[nature.com]

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