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17 Possible Causes for Abdominal Pain, Liver Biopsy showing Periportal Necrosis, Liver Function Tests Abnormal

  • Primary Sclerosing Cholangitis

    Liver function tests are usually abnormal (increased serum alkaline phosphatase (ALP) most commonly) and the bilirubin level can be raised with biliary obstruction.[royalfree.nhs.uk] A 39-year-old man presented with diarrhea and abdominal pain.[ncbi.nlm.nih.gov] He had suffered from repeated abdominal pain and cholangitis for 3 years.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    Some much-quoted early studies noted abnormalities in liver function tests (LFTs) in very obese patients taking high doses, although there was no evidence of clinically significant[ncbi.nlm.nih.gov] Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] This can be a useful test in determining the cause of your abnormal liver function.[healthline.com]

  • Hepatitis A

    Laboratory tests showed abnormal liver function tests and serological workup was consistent with acute hepatitis A infection.[ncbi.nlm.nih.gov] Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] Common clinical manifestations include high fever, maculopapular rash, neurological symptoms, coagulopathy, and abnormal liver function tests [1].[ncbi.nlm.nih.gov]

  • Aflatoxicosis

    Investigations showed abnormal liver function tests, pancytopenia and elevated serum levels of aflatoxins.[ncbi.nlm.nih.gov] Patients will appear ill with fever, jaundice, nausea, vomiting, abdominal pain, and hemorrhagic diathesis, hepatomegaly, and elevated liver function tests.[visualdx.com] Aflatoxins can cause: Nausea, vomiting, and abdominal pain Convulsions Pulmonary edema, which is fluid buildup (edema) in the lungs ('pulmon-') Cerebral edema, which is fluid[study.com]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org] Liver Abscess Abnormalities of liver function tests: Dec. serum albumin (50%); inc. serum globulin Inc. serum ALP (75%) Inc. serum bilirubin (20-25%)  10 mg/dL usually indicates[slideshare.net]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] His liver function tests became markedly abnormal 8 years after LT.[ncbi.nlm.nih.gov] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org]

  • Hepatitis B

    These results can also help determine which part of your liver may be functioning abnormally.[healthline.com] Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease, gastroenterology Symptoms None, yellowish skin, tiredness, dark urine, abdominal pain Classification[en.wikipedia.org] After ten days of TDF administration, nausea, vomiting and abdominal pain developed.[ncbi.nlm.nih.gov]

  • Isoniazid Hepatitis

    Accordingly, liver function tests were performed on 178 adolescents prior to and following administration of INH.[ncbi.nlm.nih.gov] Seven patients initially experienced excess fatigue, nausea, or abdominal pain, but waited until the onset of jaundice before seeking medical attention.[cdc.gov] Differential diagnosis Other causes of abnormal liver function tests. Other causes of hepatitis, including: Viral hepatitis.[patient.info]

  • Primary Biliary Cirrhosis

    Initially there may be few symptoms like itching or fatigue to help guide further testing The diagnosis may be made incidentally when abnormal liver functions be found on[medicinenet.com] Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] At 45 years of age, the patient complained of bloody diarrhea and abdominal pain, and she was diagnosed with ulcerative colitis by colonoscopy and histological examination[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Suspicion of the diagnosis arose after a routine blood test which revealed abnormal liver function tests.[ncbi.nlm.nih.gov] Chills Clay-colored stools Darkened urine Fever Jaundice (yellowing of the skin and eyes) Nausea Pain below the shoulder blade Right upper quadrant or middle abdominal pain[verywellhealth.com]

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