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15 Possible Causes for Abdominal Pain, Liver Biopsy showing Periportal Necrosis, Splenomegaly

  • Viral Hepatitis

    Besides features of viral hepatitis, the presence of typical abdominal pain, high serum amylase, and ultrasound or CT scan features suggested the diagnosis of acute pancreatitis[ncbi.nlm.nih.gov] She was admitted to our hospital with fever, jaundice and abdominal pain. Hepatic and pancreatic enzymes were elevated.[ncbi.nlm.nih.gov] This case report, along with the review presented, describes a patient diagnosed with acute viral hepatitis, who developed a framework of intense abdominal pain and laboratorial[ncbi.nlm.nih.gov]

  • Hepatitis B

    CASE REPORT: A 29-year-old man, with no significant prior medical history, presented with fever and massive splenomegaly.[ncbi.nlm.nih.gov] Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease, gastroenterology Symptoms None, yellowish skin, tiredness, dark urine, abdominal pain Classification[en.wikipedia.org] […] patients with chronic hepatitis B progress to cirrhosis (when the liver becomes severely scarred) they will develop signs and symptoms of liver failure, including: Jaundice Splenomegaly[hopkinsmedicine.org]

  • Hepatitis A

    Tender hepatomegaly, splenomegaly, and lymphadenopathy may occur.[patient.info] Infectious hepatitis A case of jaundice caused by hepatitis A Specialty Infectious disease, gastroenterology Symptoms Nausea, vomiting, diarrhea, dark urine, jaundice, fever, abdominal[en.wikipedia.org] Signs include hepatomegaly, lymphadenopathy and splenomegaly, though these findings vary from individual to individual, depending on general health status and age group.[symptoma.com]

  • Primary Sclerosing Cholangitis

    Full blood count – thrombocytopaenia (low platelety)may be found secondary to the portal hypertension (splenomegaly).[myvmc.com] A 39-year-old man presented with diarrhea and abdominal pain.[ncbi.nlm.nih.gov] Hepatomegaly, splenomegaly, jaundice, portal hypertension and, in more advanced cases, spider angiomata, ascites and muscle atrophy are observed.[orpha.net]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] The clinical picture strikingly resembles infectious mononucleosis with generalized malaise and splenomegaly.[annals.org] Case Report A healthy, 30-year-old woman at 32 weeks gestation presented to the emergency department with sudden-onset headache and abdominal pain.[acgcasereports.gi.org]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] At 45 years of age, the patient complained of bloody diarrhea and abdominal pain, and she was diagnosed with ulcerative colitis by colonoscopy and histological examination[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Physical exam was remarkable for digital clubbing, splenomegaly and orthodeoxia.[ncbi.nlm.nih.gov] Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.[en.wikipedia.org]

  • Generalized Lipodystrophy

    Hepatomegaly was noticed, and histological examination of a liver biopsy specimen suggested severe hepatic steatosis and periportal necrosis.[ncbi.nlm.nih.gov] Common clinical features are acanthosis nigricans, hepatomegaly with or without splenomegaly and high stature.[ncbi.nlm.nih.gov] […] lesions and abdominal pain.[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    Signs of chronic liver disease usually develop and include the following: (a) Splenomegaly (spleen enlargement).[armymedical.tpub.com] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Chills Clay-colored stools Darkened urine Fever Jaundice (yellowing of the skin and eyes) Nausea Pain below the shoulder blade Right upper quadrant or middle abdominal pain[verywellhealth.com]

  • Chronic Hepatitis

    Huge splenomegaly is seen.[radiopaedia.org] In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

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