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19 Possible Causes for Abdominal Pain, Luteinizing Hormone Low, Testicular Biopsy Abnormal

  • Leydig Cell Tumor

    CASE PRESENTATION: A 12 year old girl referred acute abdominal pain with no other clinical manifestations.[] Serum levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were inappropriately low for a post-menopausal woman, with high levels of estradiol.[] The patient presented with diffuse abdominal pain and bloating.[]

  • Orchitis

    An 11-year-old boy presented with fever and abdominal pain, and was diagnosed with retroperitoneal lymphadenitis.[] […] in mumps orchitis, have found low testosterone levels, elevated luteinizing hormone (LH) levels and an exaggerated pituitary response to LH-releasing hormone stimulation[] Pain and Hematochezia Bridging the Gap Challenge Yourself Interactive Medical Cases Image Challenge Videos in Clinical Medicine View all learning/CME Other NEJM Group Learning[]

  • Germ Cell Tumor

    CASE: A 16-year-old female patient presented with abdominal pain and an 11-cm adnexal mass on ultrasound.[] Her serum hormonal assay revealed a low estradiol level with elevated luteinizing hormone and follicular stimulating hormone levels with normal progesterone and testosterone[] Many patients with extragonadal germ cell tumors have histories of infertility, and testicular biopsy in these patients shows various abnormalities, including decreased spermatogenesis[]

  • Anorchia

    Hormonally inactive tumors often have a nonspecific presentation such as an abdominal mass and/or pain. The majority of patients present with stage I disease.[] Tests include testosterone levels (low); follicle stimulating hormone and luteinizing hormone levels (elevated); X,Y karyotype; ultrasound or magnetic resonance imaging showing[] Testicular biopsy is rarely indicated (special fixative required).[]

  • Cryptorchidism

    All children were admitted because of the inconsolable cry, abdominal pain, and the swelling of the groin.[] Tests include observable lack of testes, low testosterone levels (typical female levels), elevated follicle stimulating hormone and luteinizing hormone levels, XY karyotype[] More importantly, only testicular biopsy can nowadays determine which patient should benefit from hormonal therapy.[]

  • Congenital Absence of the Testis

    Case 1 A male child aged 11 years and nine months presented initially to a peripheral clinic with vague abdominal pain of two months duration, without any localizing features[] Tests include observable lack of testes, low testosterone levels (typical female levels), elevated follicle stimulating hormone and luteinizing hormone levels, XY karyotype[] […] spermatogenesis and should therefore, undergo a diagnostic testicular biopsy.[]

  • Gonadoblastoma

    She suffered of abdominal pain. In palpation of the abdomen, an irregular mobile mass was detected in left lower quadrant.[] Serum testing revealed primary hypogonadism pattern, elevated follicle-stimulating hormone and luteinizing hormone with low concentrations of estradiol and testosterone.[] Subsequent testicular biopsy and histopathological examination showed intratubular malignant germ cells in the testicular tubules.[]

  • Central Precocious Puberty

    Patients with HWW syndrome usually present symptoms such as dysmenorrhea, abdominal pain, pelvic mass, and purulent vaginal discharge.[] Although basal levels of luteinizing hormone and follicle-stimulating hormone are low, similar to what is expected in the pre-pubertal period, testosterone levels are high[] A testicular biopsy was not done. Our patient was treated with four cycles of preoperative chemotherapy (cisplatin, alternating with carboplatin/dox-orubicin).[]

  • Seminal Vesicle Disorder

    Lower abdominal pain is typical, the pain can spread locally in pelvic area to perineum area or the groins.[] These patients usually have low serum luteinizing hormone (LH) levels as well.[] Symptoms of seminal vesiculitis can include vague back or lower abdominal pain; penile, scrotal, or perineal pain; painful ejaculation; hematospermia ; irritative and obstructive[]

  • Infertility

    Here is discussed a challenging case of a 30-year-old woman with no living child and secondary infertility who presented with a large abdominal mass and severe abdominal pain[] hormone levels. 43 Other low-cost methods of monitoring for ovulation, although less effective, include basal body temperature measurements and cervical mucus changes. 42[] In some instances, a biopsy of testicular tissue can identify infertility problems such as sperm production, abnormal growths, tumors, or underdeveloped reproductive organs[]

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