Create issue ticket

17 Possible Causes for Abdominal Pain, Mutation in the CDK6 Gene, Personality Change

  • Malignant Gastric Neoplasm

    Most cancers are caused by gene changes that happen during a person’s lifetime, but a person’s cancer risk can be higher if they have one of these rare inherited mutations[debbiesdream.org] A 56-year-old man with complaint of upper abdominal pain exhibited adenocarcinoma upon histopathologic examination of biopsy specimens.[ncbi.nlm.nih.gov] Figure 5: Integrated molecular description of gastric cancer. a , Mutations, copy-number changes and translocations for select genes are shown across samples organized by[nature.com]

  • Gastric Adenocarcinoma

    Because there is no one risk factor directly associated with gastric cancer, there is no strict lifestyle change that can greatly decrease a person's risk of developing gastric[oncolink.org] Abdominal pain is a frequent complaint in the pediatric emergency department.[ncbi.nlm.nih.gov] In Pt2, the SETBP1 gene (p.S944N) was mutated, as it is in myeloid malignancies ( 20 ), together with amplification of AKAP9 and CDK6 (cyclin-dependent kinase 6).[pnas.org]

  • Glioblastoma Multiforme

    General symptoms for metastatic brain tumors include: Headaches Weakness on one side of the body Problems with balance Seizures Behavior, memory and personality changes Glioblastoma[uwhealth.org] Case 5: Subependymal spread of glioblastoma multiforme A 60-year-old man was admitted for left-sided abdominal pain of approximately 3 weeks.[sajr.org.za] The inherited predisposition factors in pediatric HGG are as follows: germline mutations in tumor suppressor genes TP53 and neurofibromin 1 (NF1); oncogenic NTRK fusions [[doi.org]

  • Biliary Carcinoma

    If you are concerned about any changes you experience, please talk with your doctor.[cancer.net] pain (7%), and phlebitis (6%).[ncbi.nlm.nih.gov] This tendency is the same as that for K-ras mutations and the pancreaticobiliary maljunction may override the effect of p53 gene mutations.[atlasgeneticsoncology.org]

  • Pancreatic Neoplasm

    Psychosocial Assess for the presence of irritability, depression, and personality changes.[medical-dictionary.thefreedictionary.com] A 66-year-old man with abdominal pain was noted to have a complex pancreatic head and uncinate process mass on imaging.[ncbi.nlm.nih.gov] Thus when mutations in the CDKN2A gene disrupt the function of p16(INK4), there is improper progression from the G1 to the S phase, allowing continued, uncontrolled cell proliferation[ncbi.nlm.nih.gov]

  • Gastric Cancer

    Because there is no one risk factor directly associated with gastric cancer, there is no strict lifestyle change that can greatly decrease a person's risk of developing gastric[oncolink.org] Only mild symptoms of dyspepsia and abdominal pain are usually seen in the early stages.[symptoma.com] Figure 5: Integrated molecular description of gastric cancer. a, Mutations, copy-number changes and translocations for select genes are shown across samples organized by molecular[nature.com]

  • Rhabdomyosarcoma

    Shrieve, Demographics, stage distribution, and relative roles of surgery and radiotherapy on survival of persons with primary prostate sarcomas, Cancer Medicine, 7, 12, (6030[doi.org] pain Vomiting Constipation Arm or leg muscle Mass, growth, lump, or swelling in the leg or arm that may or may not be painful If the cancer has spread, the child may experience[cancer.net] The discovery that p16 gene is mutated or deleted in a striking proportion of human tumors raised the possibility that abnormalities in p16 might predispose to cancer development[ncbi.nlm.nih.gov]

  • Medulloblastoma

    […] in sensation on one side of the body Seizures Unusual sleepiness or change in energy level Change in personality or behavior Unexplained weight loss or weight gain More advanced[columbianeurosurgery.org] During adjuvant chemotherapy, two patients reported severe abdominal pain and obstipation that was diagnosed as subileus with spontaneous remission in both cases (10%).[bmccancer.biomedcentral.com] Poor prognosis: Group 3, MYC amplification, photoreceptor/GABAergic gene expression Intermediate prognosis: Group 4, gene expression of neuronal/glutamatergic, CDK6 amplification[en.wikipedia.org]

  • Acute Myelomonocytic Leukemia

    CML is an acquired leukemia, resulting from a change in a person's DNA. This change results in an uncontrolled growth of white cells.[nationalcmlsociety.org] pain.[ncbi.nlm.nih.gov] In one-third we observed chromosome abnormalities (e.g. trisomy 8, del20q) and gain or loss of genes (e.g. NF1, RB1 and CDK6 ).[bmccancer.biomedcentral.com]

  • Noonan Syndrome-Like Disorder with Juvenile Myelomonocytic Leukemia

    A person’s genes are made of DNA. Both copies of the person’s genes are checked for possible changes.[stjude.org] abdominal pain (caused by abnormal blood cells accumulating in organs like the kidneys, liver, and spleen) Diagnosis A doctor who suspects a child has leukemia may order[rchsd.org] In one-third we observed chromosome abnormalities (e.g. trisomy 8, del20q) and gain or loss of genes (e.g. NF1, RB1 and CDK6 ).[bmccancer.biomedcentral.com]

Similar symptoms