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121 Possible Causes for Abnormal ECG, Clumsy Gait, Pediatric Disorder

  • Duchenne Muscular Dystrophy

    BACKGROUND AND PURPOSE: Duchenne muscular dystrophy (DMD) is a lethal progressive pediatric muscle disorder and genetically inherited as an X-linked disease that caused by[ncbi.nlm.nih.gov] The PR interval gradually increased with age, but no ECGs showed an abnormally prolonged PR interval.[ncbi.nlm.nih.gov] Additional early signs and symptoms include: Developmental delay Muscle weakness Clumsiness Waddling gait Difficulty or inability to perform activities such as climbing stairs[pfizer.com]

  • Becker Muscular Dystrophy

    Little is known about parental motivations and expectations for clinical trials for rare pediatric disorders.[ncbi.nlm.nih.gov] One of them has an abnormal ECG that showed right ventricular hypertrophy and sinus tachycardia and the others have abnormal echocardiograms (ejection fraction ranging from[doi.org] Walking on the toes or balls of the feet Clumsiness, falling often Trouble climbing stairs Difficulty rising from a lying or sitting position Larger-than-normal calves that[webmd.com]

  • Blue Rubber Bleb Nevus Syndrome

    Phone: 617-636-5025 Fax #: 617-636-8122 Pediatric surgery, pediatric trauma, congenital disorders requiring surgery in newborns, GI inflammatory diseases in children, pediatric[floatinghospital.org] Posted on July 18, 2019 Languages: English Fax: (410) 573-9413 Conditions I Treat abnormal ecg abnormal stress test acute bacterial endocarditis alcoholic cardiomyopathy amyloidosis[medstarhealth.org] , imbalance or clumsy movement) and itching.[czytelniamedyczna.pl]

  • Rheumatic Chorea

    disorder, tic disorders, and autism, which they call PANDAS, for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus infection.[ninds.nih.gov] […] on ECG.[childrensheartinstitute.org] Chorea interferes with voluntary movements and causes a clumsy gait, dropping and spilling and explosive bursts of dysarthric speech.[patient.info]

  • Friedreich Ataxia

    Leigh syndrome (subacute necrotizing encephalomyopathy) is a rare, highly morbid and fatal pediatric disorder that results in severe neurological and neuromuscular dysfunction[bioelectron.com] Approximately 65% of patients with FA have abnormal ECG findings .[flipper.diff.org] General clumsiness and gait ataxia are usually the first signs to appear, often followed by pyramidal signs, upper-limb ataxia and dysarthria.[orpha.net]

  • Infantile Hemiplegia

    [Crossref] Mak MK (2010) Reaching and grasping a moving target is impaired in children with developmental coordination disorder. Pediatr Phys Ther 22: 384-391.[oatext.com] Seizures and ECG abnormalities should be properly treated and monitored while triggers and irregular sleeping patterns should be avoided as much as possible.[orpha.net] Ataxic Gait Most commonly seen in cerebellar disease, this gait is described as clumsy, staggering movements with a wide-based gait.[web.archive.org]

  • Wilson Disease

    disorders Genotype–phenotype correlation Summary Chapter 13: Other organ involvement and clinical aspects of Wilson disease Karolina Dziezyc, Tomasz Litwin and Anna Czlonkowska[elsevier.com] Out of 51 patients 22 had at least one ECG abnormality.[ncbi.nlm.nih.gov] Tremors, involuntary muscle movements, clumsy gait and speech difficulties usually improve with treatment for Wilson's disease.[mayoclinic.org]

  • Rett Syndrome

    El-Bitar, Degenerative Disorders Primarily of Gray Matter, Swaiman's Pediatric Neurology, 10.1016/B978-1-4377-0435-8.00041-X, (518-543), (2012). Eveline E. O.[doi.org] ], but manually calculated to be 440 ms]), no cardiac abnormalities (PR interval: 104 ms, QRS duration: 78 ms), and generalised anxiety disorder (ICD-10-CM Diagnosis Code[ncbi.nlm.nih.gov] These mice do not express Mecp2 at all and they display the same symptoms as humans, such as normal development until about 6 weeks, regression, reduced movement, clumsy gait[doi.org]

  • SHORT Syndrome

    Pediatric disorders of sex development. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 13th ed.[medlineplus.gov] Medication aimed at correcting the ECG abnormality – the shortened QT interval – has been tried.[en.wikipedia.org] It doesn't always cause symptoms, but when it does it can lead to neurological symptoms such as clumsiness, difficulty walking or an abnormal gait (e.g. limping), nerve pain[verywellhealth.com]

  • Glycogen Storage Disease Type 2

    Nomenclature for Conditions based upon “Naming and Counting Disorders (Conditions) Included in Newborn Screening Panels.” Pediatrics. 2006; 117 (5) Suppl: S308-S314.[hrsa.gov] No cardiac abnormality was revealed by CXR, ECG, or echocardiography; CK remained normal. Head lag and truncal hypotonia were noted at 4 months of age.[doi.org] Patients with the latter two types may manifest with primarily neurologic symptoms of clumsiness, gait disturbance, worsening of coordination, and fine motor skills, or with[dx.doi.org]

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