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288 Possible Causes for Abnormal Gait, Apathy, Extremity Ataxia

  • Parkinson's Disease

    Apathy was identified in 31.6%; apathy without depression was present in 33.3% of patients.[ncbi.nlm.nih.gov] […] insomnia. 54 Less frequently reported effects in 1% to 5% of patients are depression, anxiety and irritability, hallucinations, confusion, anorexia, dry mouth, constipation, ataxia[ncbi.nlm.nih.gov] […] disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hyperreflexia Increased reflexes[rarediseases.info.nih.gov]

  • Pernicious Anemia

    We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] Neurological symptoms may include muscular weakness and abnormal gait.[orpha.net] ), ataxia and positive Babinski reflexes.[doi.org]

  • Conversion Disorder

    Her symptoms progressed to include low back pain, episodes of jerking and tingling of her upper extremities, and ataxia of her trunk and extremities.[journals.lww.com] The modified gait abnormality rating scale (GARS-M) may be useful for quantifying gait abnormalities in these individuals.[ncbi.nlm.nih.gov] There may also be exaggerated trembling or shaking of one or more extremities or the whole body.[traumadissociation.com]

  • Huntington's Disease

    Apathy severity increases in the motormanifest stages of Huntington's disease. HDGECs can adequately assess their level of apathy on a self-report questionnaire.[ncbi.nlm.nih.gov] Muscles may become extremely rigid and gait may show signs of ataxia. Chorea may also be mixed with other movement disorders such as dystonia.[encyclopedia.com] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com]

  • Creutzfeldt Jakob Disease

    Whether symptoms develop gradually or abruptly, mental decline progresses, often producing such symptoms as neglect of personal hygiene, apathy, and irritability.[web.archive.org] , gait abnormalities, dementia, dysarthria, ocular dysmetria, and hyporeflexia or areflexia in the lower extremities.[doi.org] People with CJD will have ataxia, or difficulty controlling body movements, abnormal gait, speech, and dementia. It is always fatal, and there is no cure.[medicalnewstoday.com]

  • Vitamin B12 Deficiency

    Severe vitamin B(12) deficiency produces a cluster of neurological symptoms in infants, including irritability, failure to thrive, apathy, anorexia, and developmental regression[ncbi.nlm.nih.gov] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[merckmanuals.com] Neurologic signs and symptoms: Numbness—tingling Weakness of legs, arms, trunk Impaired vibration—position sense Abnormal reflexes Unsteady or abnormal gait Balance problems[b12awareness.org]

  • Neurological Disorder

    FvFTD, exemplified here, often presents first to a psychiatrist, typically with a blunting of emotions, apathy, and egocentricity.[doi.org] Disorganization of motor function in two extremities (see 11.00D1), resulting in an extreme limitation (see 11.00D2) in the ability to stand up from a seated position, balance[ssa.gov] […] encephalopathy any disorder or disease of the brain ataxia, ataxy, dyssynergia, motor ataxia inability to coordinate voluntary muscle movements; unsteady movements and staggering gait[vocabulary.com]

  • Whipple Disease

    Introduction Whipple's disease (WD) is a rare condition caused by infection with Gram-positive bacilli ( Tropheryma whipplei ) characterised by fever, diarrhoea, arthropathy, apathy[jmedicalcasereports.com] Results Subject 1 A 54-year-old man presented with hypersomnia, weight gain, lower extremity weakness, dysarthria, confusion, and gait ataxia.[ajnr.org] abnormalities, seizures, coma.[patient.info]

  • Wernicke Encephalopathy

    Manifestations of thiamine deficiency in infants are constipation, agitation, apathy, vomiting, lack of appetite, and later, diarrhea, grunting, nystagmus, convulsions, unconsciousness[emedicine.medscape.com] […] voice, inattention, ataxia, and binocular diplopia after a voluntary 59-kg weight loss over 5 months.[ncbi.nlm.nih.gov] Wernicke encephalopathy (WE) commonly presents with oculomotor abnormalities, gait ataxia and confusion.[ncbi.nlm.nih.gov]

  • Subacute Combined Degeneration of Spinal Cord

    As the disease worsens, symptoms may include any of the following: Clumsiness, stiff or awkward movements Change in mental state, such as memory problems, irritability, apathy[nlm.nih.gov] Case Presentation: A 28‐year‐old nursing student with a history of bipolar disorder presented to Tucson Medical Center with symptoms of ataxia and bilateral lower‐extremity[shmabstracts.com] Numbness of the limbs and trunk is an early symptom; weakness, clumsiness and spasticity, abnormal reflexes, gait ataxia develop later.[neuroanatomy.wisc.edu]

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