Create issue ticket

85 Possible Causes for Abnormal Gait, Aspiration Pneumonia, Deep White Matter Changes

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[ncbi.nlm.nih.gov] ., face drooping, hemiparesis/hemiplegia, inability to lift ipsilateral arm or abnormal gait Contralateral sensory loss Contralateral homonymous hemianopia Dysphasia Dysphagia[symptoma.com]

  • Huntington's Disease

    Both deep grey matter and to a lesser degree white matter are involved in HD.[radiopaedia.org] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com] DPEJ placement appears to decrease recurrent aspiration pneumonia in patients with history of aspiration pneumonia.[ncp.sagepub.com]

  • Machado-Joseph Disease

    Magnetic resonance spectroscopy (MRS) of the deep white matter has demonstrated changes indicative of axonal dysfunction, although MRI in the same study did not reveal any[symptoma.com] walking due to muscle spasms (spastic gait) Poor reflexes Type III (MJD-III) Between 40-70 years of age Symptoms slowly worsen over time Muscle twitching Numbness, tingling[rarediseases.about.com] The cause of death for those who die early is often aspiration pneumonia. MJD is incurable, but some symptoms of the disease can be treated.[peninsulamedical.moneomed.com]

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[medigoo.com] Aspiration pneumonia. Decubitus ulcers. Caregiver burden and stress: this should be considered a complication of any dementia, including vascular dementia.[patient.info]

  • Lafora Disease

    matter signal, Deep frontoparietal cerebral changes at 10 years of age Child onset: Weakness Clinical Weakness: Proximal; Symmetric Muscle size: Calf hypertrophy Subgroup[neuromuscular.wustl.edu] Lafora disease causes seizures, muscle spasms, difficulty walking, dementia, and eventually death.[diseaseinfosearch.org] These episodes increase in severity and number until the patient eventually dies from a massive seizure, status epilepticus or aspiration pneumonia.[sciencedaily.com]

  • Infantile Neuroaxonal Dystrophy

    In one patient (juvenile case) with lesions in the deep frontal white matter, an elevated diffusion pattern was evident.[ajnr.org] Clinical Onset before age 20 years Psychomotor regression Gait abnormalities Prominent expressive language difficulties Psychiatric/behavioral abnormalities including autistic-like[ncbi.nlm.nih.gov] Death occurs as a result of secondary illnesses such as aspiration pneumonia, associated with bulbar dysfunction.[symptoma.com]

  • Hallervorden-Spatz Syndrome

    Brain stem nuclei had similar changes. The high signal intensity lesions in the deep cerebral white matter and dentate nuclei were unchanged.[ajnr.org] The early onset childhood group had uniform presentation with developmental delay, recurrent falls, gait abnormalities, cognitive deterioration and dystonia.[ncbi.nlm.nih.gov] The anaesthetic concerns include difficult airway, aspiration pneumonia, dehydration, and post-operative respiratory, and renal insufficiency.[ijaweb.org]

  • CADASIL Syndrome

    MR imaging lesion load correlated with some clinical features including stroke and dementia, whereas depression is more common in individuals with deep white matter changes[ajnr.org] This can result in an unsteady and wide based gait or sometimes an abnormal gait due to small steps. Should antiplatelet agents such as Aspirin be prescribed in CADASIL?[cambridgestroke.com] Table 5 Primary causes of death in 50 CADASIL subjects (classified according to ICD10) Cause No. of subjects (%) Pneumonia (ICD10: J12–18) § 13 (26) Aspiration pneumonia ([academic.oup.com]

  • Glycogen Storage Disease Type 2

    matter signal, Deep frontoparietal cerebral changes at 10 years of age Child onset: Weakness Clinical Weakness: Proximal; Symmetric Muscle size: Calf hypertrophy Subgroup[neuromuscular.wustl.edu] abnormalities Muscle pain Difficulty climbing stairs Frequent falls Scapular winging Respiratory Frequent infections Respiratory insufficiency Cardio-respiratory failure[cuh.nhs.uk] Also, blunted swallowing reflexes may lead to life-threatening aspiration pneumonia.[symptoma.com]

  • Ataxia Telangiectasia

    Occasionally, lesions that are consistent with small vessel ischemic or degenerative changes have been noted in the deep white matter of the cerebral hemispheres.[appliedradiology.com] The records of all patients seen at the Ataxia-Telangiectasia Clinical Center from July 1, 1995 to April 1, 1997 were reviewed to determine age of onset of gait abnormality[ncbi.nlm.nih.gov] Early identification of swallowing alterations and rehabilitation could decrease the risk of aspiration pneumonia.[ncbi.nlm.nih.gov]

Similar symptoms