Create issue ticket

170 Possible Causes for Abnormal Gait, Ataxia, Deep White Matter Changes

  • Pineal Gland Cyst

    Today I received my results stating I have a few like foci of increased T2 signal in the deep periventricular white matter regions.[healthcaremagic.com] If narrowing of the cerebral aqueduct occurs, many neurological symptoms may exist, including headaches, vertigo, nausea, muscle fasciculations, eye sensitivity, and ataxia[en.wikipedia.org] Less frequently, patients present with ataxia, motor and sensory impairment, mental and emotional disturbances, epilepsy, circadian rhythm disturbances, hypothalamic dysfunction[ncbi.nlm.nih.gov]

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[ncbi.nlm.nih.gov] The first patient (female, 50 years old) had dysarthria, nystagmus and trunk ataxia on admission. Her blood alcohol level was 2.3‰.[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    Consistent with this reduction, we showed that changes in diffusion indices of tissue damage within major clinically relevant white matter (corpus callosum and corticospinal[ncbi.nlm.nih.gov] A key symptom associated with PPMS is difficulty walking. This may result from the damage to the spinal cord that occurs with PPMS.[medicalnewstoday.com] Spastic paraparesis and progressive ataxia are principal symptoms in this subset of patients.[symptoma.com]

  • Hallervorden-Spatz Syndrome

    Brain stem nuclei had similar changes. The high signal intensity lesions in the deep cerebral white matter and dentate nuclei were unchanged.[ajnr.org] The early onset childhood group had uniform presentation with developmental delay, recurrent falls, gait abnormalities, cognitive deterioration and dystonia.[ncbi.nlm.nih.gov] The patient presented with a slowly progressive illness with seizures, extrapyramidal symptoms, cerebellar ataxia, dementia, spasticity, myoclonic movements and a severe demyelinating[ncbi.nlm.nih.gov]

  • Machado-Joseph Disease

    Magnetic resonance spectroscopy (MRS) of the deep white matter has demonstrated changes indicative of axonal dysfunction, although MRI in the same study did not reveal any[symptoma.com] walking due to muscle spasms (spastic gait) Poor reflexes Type III (MJD-III) Between 40-70 years of age Symptoms slowly worsen over time Muscle twitching Numbness, tingling[rarediseases.about.com] Cerebellar Ataxia Rehabilitation Trialists Collaboration. Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases.[ncbi.nlm.nih.gov]

  • Ataxia Telangiectasia

    Occasionally, lesions that are consistent with small vessel ischemic or degenerative changes have been noted in the deep white matter of the cerebral hemispheres.[appliedradiology.com] The records of all patients seen at the Ataxia-Telangiectasia Clinical Center from July 1, 1995 to April 1, 1997 were reviewed to determine age of onset of gait abnormality[ncbi.nlm.nih.gov] Ataxia-telangiectasia is an autosomal recessive disease characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, high incidence of[ncbi.nlm.nih.gov]

  • Huntington's Disease

    Both deep grey matter and to a lesser degree white matter are involved in HD.[radiopaedia.org] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com] We screened 89 patients with a Huntington's disease-like phenotype without the HD-gene mutation and 178 patients with genetically unclassified cerebellar ataxia for the mutation[ncbi.nlm.nih.gov]

  • Hereditary Cerebellar Degeneration

    Axial T2 image shows signal change affecting the deep cerebellar white matter ( arrow s).[ajnr.org] Clinical signs are varied, with some patients having limb and gait ataxia along with episodic headaches or nausea, and others having gait ataxia, speech difficulty, and abnormal[encyclopedia.com] In several of the hereditary ataxias, the causative gene plays an important role in DNA repair: ataxia telangiectasia and ataxia telangiectasia-like disorder, and ataxia with[ncbi.nlm.nih.gov]

  • Diffuse Cerebral Sclerosis of Schilder

    change in the deep white matter.[doi.org] The most common symptoms are usually behavioral changes such as abnormal withdrawal or aggression, poor memory, and poor school performance.[ninds.nih.gov] Late-onset krabbe disease (lokd) has first symptoms at ages 5 to 10 years, consisting of focal neurological signs, hemiparesis, cerebellar ataxia, cortical blindness, and[icd9data.com]

  • Creutzfeldt Jakob Disease

    Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] People with CJD will have ataxia, or difficulty controlling body movements, abnormal gait, speech, and dementia. It is always fatal, and there is no cure.[medicalnewstoday.com] Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding.[ncbi.nlm.nih.gov]

Similar symptoms