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110 Possible Causes for Abnormal Gait, Deep White Matter Changes, Paresthesia

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[] Doctors may refer to the tingling sensations as paresthesia. Here we look at possible causes, diagnosis, and treatment options.[]

  • Primary Progressive Multiple Sclerosis

    Consistent with this reduction, we showed that changes in diffusion indices of tissue damage within major clinically relevant white matter (corpus callosum and corticospinal[] A key symptom associated with PPMS is difficulty walking. This may result from the damage to the spinal cord that occurs with PPMS.[] Symptoms in-clude pain, weakness, numbness, tingling, paralysis, tremors, and muscle dysfunction.[]

  • Adult Polyglucosan Body Disease

    MRI of the brain and spinal cord reveals the following: Paraventricular, subcortical, and deep white matter changes that may include involvement of the upper pons, superior[] Progressive spasticity and weakness are also present due to upper and lower motor neuron involvement and patients have difficulty walking.[] […] matter abnormalities (MRI) polyglucosan bodies (round intracellular inclusions) found in neuronal and astrocytic processes peripheral neuropathy distal sensory impairment paresthesias[]

  • Pineal Gland Cyst

    Today I received my results stating I have a few like foci of increased T2 signal in the deep periventricular white matter regions.[] […] old iv had strange symptoms since a bang to the head such as migraines, dizzy, nausea, hallucinations at night and waking up screaming, depression/anxiety, blurred vision, tingling[] Strange headaches, tingling and pressure in my head I had a strange headaches that were not like regular headaches.[]

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([] The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[] Opsoclonus Myoclonus Orthostatic Hypotension O’Sullivan-McLeod Syndrome Overuse Syndrome Pain – Chronic Pantothenate Kinase-Associated Neurodegeneration Paraneoplastic Syndromes Paresthesia[]

  • CADASIL Syndrome

    MR imaging lesion load correlated with some clinical features including stroke and dementia, whereas depression is more common in individuals with deep white matter changes[] This can result in an unsteady and wide based gait or sometimes an abnormal gait due to small steps. Should antiplatelet agents such as Aspirin be prescribed in CADASIL?[] At the neurological examination, she presented psychomotor slowness, confusion, difficulty in speech, left lateral hemianopia, and paresthesias on the left side of the face[]

  • Machado-Joseph Disease

    Magnetic resonance spectroscopy (MRS) of the deep white matter has demonstrated changes indicative of axonal dysfunction, although MRI in the same study did not reveal any[] walking due to muscle spasms (spastic gait) Poor reflexes Type III (MJD-III) Between 40-70 years of age Symptoms slowly worsen over time Muscle twitching Numbness, tingling[] Early symptoms and signs of neuropathy are paresthesia and hyperesthesia of the extremities, with disappearance of deep tendon reflexes.[]

  • Progressive Multifocal Leukoencephalopathy

    This suggests that increasing severity of cortical and deep atrophy, increasing confluence and extent of white matter lesions, spread of disease across the corpus callosum[] Limb weakness, gait abnormalities, visual loss, and altered mental status were the commonest initial complaints.[] The patient experienced additional paresthesia on the left side of her face and swallowing difficulties.[]

  • Metachromatic Leukodystrophy

    Markers serum/urine arylsulfatase A levels: reduced MRI Characterized by bilateral symmetrical confluent areas of periventricular deep white matter signal change, in particular[] Diagnosis is based on the onset of neurological symptoms, presence of gait abnormalities, spasticity, decreased muscle stretch reflexes and neuro-radiological evidence of[] Common findings associated with peripheral neuropathy may include muscle weakness; pain; numbness; redness; and/or burning or tingling sensations in the affected areas, especially[]

  • Huntington's Disease

    Both deep grey matter and to a lesser degree white matter are involved in HD.[] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[] There have been reports of patients who suffered permanent losses of cervical spinal cord function during this practice; however, these cases employed long needles and paresthesia[]

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