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124 Possible Causes for Abnormal Gait, Deep White Matter Changes, Psychosis

  • Stroke

    Post-stroke emotional difficulties include anxiety, panic attacks, flat affect (failure to express emotions), mania, apathy and psychosis.[en.wikipedia.org] Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[ncbi.nlm.nih.gov]

  • Huntington's Disease

    The objective was to describe a case of juvenile Huntington's disease that first presented with seizures and psychosis.[ncbi.nlm.nih.gov] Both deep grey matter and to a lesser degree white matter are involved in HD.[radiopaedia.org] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com]

  • Creutzfeldt Jakob Disease

    Other psychological features, such as anxiety, depression, paranoia, obsessive-compulsive symptoms, and psychosis, occur in 1/3 of cases.[symptoma.com] Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] People with CJD will have ataxia, or difficulty controlling body movements, abnormal gait, speech, and dementia. It is always fatal, and there is no cure.[medicalnewstoday.com]

  • Subacute Sclerosing Panencephalitis

    ., mania, psychosis, and catatonia) have also been reported during the initial course of the illness.[ijpm.info] Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] Soon after, she developed difficulty walking and often talked to a “friend” who was not present.[pediatrics.aappublications.org]

  • CADASIL Syndrome

    After resolution of her psychosis, she showed persistent distractibility, which indicated signs of cognitive impairment.[ncbi.nlm.nih.gov] MR imaging lesion load correlated with some clinical features including stroke and dementia, whereas depression is more common in individuals with deep white matter changes[ajnr.org] This can result in an unsteady and wide based gait or sometimes an abnormal gait due to small steps. Should antiplatelet agents such as Aspirin be prescribed in CADASIL?[cambridgestroke.com]

  • Binswanger Disease

    Brain Lesions and Cognitive Function in Late-Life Psychosis . British Journal of Psychiatry, Vol. 158, Issue. 01, p. 76.[bjp.rcpsych.org] OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[medigoo.com]

  • Hyponatremia

    We would suggest that this patient's polydipsia and hyponatremia are most likely a result of his ingestion of a toxic dose of a long-acting agent known to cause secondary psychosis[ncbi.nlm.nih.gov] In the brain MRI, millimeter-sized chronic microangiopathic ischemic signal changes were observed in the periventricular deep white matter; no mass image was seen in the pituitary[reumatologiaclinica.org] walking.[casesjournal.biomedcentral.com]

  • Dementia

    Agitation and psychosis are common among older adults with dementia and are challenging to manage.[ncbi.nlm.nih.gov] It may be particularly related to frontal deep white matter lesions. 16 Cognitive and behavioral changes in SVD are due to disruption of the frontal cortico-subcortical circuit[doi.org] walking experiencing behaviour changes that may escalate and include aggression.[web.archive.org]

  • Alcohol Dementia

    […] or commonly as alcoholic psychosis .[healthhype.com] The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[gponline.com] This disorder is characterized by paralysis of eye movements, abnormal stance and gait, and markedly deranged mental function.[newenglandnightingales.com]

  • Multi-Infarct Dementia

    A variety of patterns of behavioral changes may be observed in MID, depression, psychosis, and personality change are common.[ncbi.nlm.nih.gov] Several pathogenic mechanisms appear implicated in the causation the deep white matter changes of Binswanger's disease, and hypoxia-ischemia resulting from watershed injury[web.archive.org] Common neurological signs (e.g., abnormal reflexes, weakness of an extremity, gait disturbance) are discussed in the “Diagnostic Features” section.[courses.lumenlearning.com]

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