Create issue ticket

57 Possible Causes for Abnormal Gait, Deep White Matter Changes, Scanning Speech

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[ncbi.nlm.nih.gov] The most common types of tests used are echocardiograms and ultrasound scans.[headway.org.uk]

  • Primary Progressive Multiple Sclerosis

    Consistent with this reduction, we showed that changes in diffusion indices of tissue damage within major clinically relevant white matter (corpus callosum and corticospinal[ncbi.nlm.nih.gov] A key symptom associated with PPMS is difficulty walking. This may result from the damage to the spinal cord that occurs with PPMS.[medicalnewstoday.com] He published what now is known as the "Charcot Triad", consisting in nystagmus, intention tremor, and telegraphic speech (scanning speech) [120] Charcot also observed cognition[en.wikipedia.org]

  • Ataxia Telangiectasia

    Occasionally, lesions that are consistent with small vessel ischemic or degenerative changes have been noted in the deep white matter of the cerebral hemispheres.[appliedradiology.com] The records of all patients seen at the Ataxia-Telangiectasia Clinical Center from July 1, 1995 to April 1, 1997 were reviewed to determine age of onset of gait abnormality[ncbi.nlm.nih.gov] A baby girl, normal at birth, manifested abnormalities of gait and persistent watery nasal discharge before the age of 2 years.[jamanetwork.com]

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[medigoo.com] speech (ataxic dysarthria ) abnormal staccato-like speech due to a lesion of the cerebellum or cerebellar pathways scaphocephaly (dolichocephaly) premature closure of the[strokecenter.org]

  • Hereditary Cerebellar Degeneration

    Axial T2 image shows signal change affecting the deep cerebellar white matter ( arrow s).[ajnr.org] Clinical signs are varied, with some patients having limb and gait ataxia along with episodic headaches or nausea, and others having gait ataxia, speech difficulty, and abnormal[encyclopedia.com] speech Slow enunciation with a tendency to hesitate at the beginning of a word or syllable Tremor Rhythmic, alternating, oscillatory movement of a limb as it approaches a[msdmanuals.com]

  • CADASIL Syndrome

    MR imaging lesion load correlated with some clinical features including stroke and dementia, whereas depression is more common in individuals with deep white matter changes[ajnr.org] This can result in an unsteady and wide based gait or sometimes an abnormal gait due to small steps. Should antiplatelet agents such as Aspirin be prescribed in CADASIL?[cambridgestroke.com] Mutation Scanning: A process by which a segment of DNA is screened via one of a variety of methods to identify variant gene region(s).[unicare.com]

  • Hallervorden-Spatz Syndrome

    Brain stem nuclei had similar changes. The high signal intensity lesions in the deep cerebral white matter and dentate nuclei were unchanged.[ajnr.org] The early onset childhood group had uniform presentation with developmental delay, recurrent falls, gait abnormalities, cognitive deterioration and dystonia.[ncbi.nlm.nih.gov] "Patients with atypical Hallervorden-Spatz syndrome who present with speech and psychiatric disorders and whose brain MRI scans have the eye of the tiger sign should undergo[auntminnie.com]

  • Diffuse Cerebral Sclerosis of Schilder

    change in the deep white matter.[doi.org] The most common symptoms are usually behavioral changes such as abnormal withdrawal or aggression, poor memory, and poor school performance.[ninds.nih.gov] Case Report A 9-year-old girl presented with acute right side hemiparesis and slurring of speech.[jmgims.co.in]

  • Cerebellar Ataxia

    Axial T2 image shows signal change affecting the deep cerebellar white matter ( arrow s).[ajnr.org] The study reports that among the remaining 29 patients, 25 required no gait aid, but had an abnormal gait, and four patients had normal gait. ### About Mayo Clinic Mayo Clinic[eurekalert.org] speech Slow enunciation with a tendency to hesitate at the beginning of a word or syllable Tremor Rhythmic, alternating, oscillatory movement of a limb as it approaches a[merckmanuals.com]

  • Congenital Muscular Dystrophy

    Apparent diffusion coefficient (ADC) map may reveal increased signal intensity and apparent diffusion coefficient values in the periventricular and deep white matters.[ncbi.nlm.nih.gov] Persons affected with RSMD1 experience difficulty walking due to thigh muscle weakness, spinal rigidity, and mild Achilles tendon tightness.[disabled-world.com] Cerebral involvement was also impressive with mental retardation and speech delay manifesting in more than half of the patients.[doi.org]

Similar symptoms