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170 Possible Causes for Abnormal Gait, Deep White Matter Changes, Seizure

  • Stroke

    Early features include: loss of grey-white matter differentiation, and hypoattenuation of deep nuclei: lentiform nucleus changes seen as early as 1 hour after occlusion, visible[radiopaedia.org] Asymmetric step length is a common abnormal gait pattern in hemiplegic stroke patients.[ncbi.nlm.nih.gov] Twenty patients (40%) had a single seizure, and most seizures (34, or 68%) were simple partial seizures or partial seizures with 2 generalization.[doi.org]

  • Pineal Gland Cyst

    Today I received my results stating I have a few like foci of increased T2 signal in the deep periventricular white matter regions.[healthcaremagic.com] We report a new complication of intracystic hemorrhage in a large pineal gland cyst in a 40-year-old man with new onset seizures.[ncbi.nlm.nih.gov] […] was once believed that smaller cysts (less than 5.0 mm) were usually asymptomatic, but for larger cysts (greater than 5.0 mm), symptoms could include headache, unexpected seizures[en.wikipedia.org]

  • Binswanger Disease

    OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[medigoo.com] Clinton suffers from “Dementia, Seizures and Black-outs.” In fact, the Doctor made note that Clinton’s conditions are “considerably worse” than in 2013.[globalresearch.ca]

  • Lafora Disease

    matter signal, Deep frontoparietal cerebral changes at 10 years of age Child onset: Weakness Clinical Weakness: Proximal; Symmetric Muscle size: Calf hypertrophy Subgroup[neuromuscular.wustl.edu] Lafora disease causes seizures, muscle spasms, difficulty walking, dementia, and eventually death.[diseaseinfosearch.org] […] the seizure latency and duration.[doi.org]

  • Diffuse Cerebral Sclerosis of Schilder

    change in the deep white matter.[doi.org] The most common symptoms are usually behavioral changes such as abnormal withdrawal or aggression, poor memory, and poor school performance.[ninds.nih.gov] Clinical findings Onset at age 5 and 10 with reversal of neurologic milestones, seizures, ataxia, Addison's disease, degeneration of visual and auditory function.[medical-dictionary.thefreedictionary.com]

  • Creutzfeldt Jakob Disease

    Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] People with CJD will have ataxia, or difficulty controlling body movements, abnormal gait, speech, and dementia. It is always fatal, and there is no cure.[medicalnewstoday.com] Seizures are known to occur in Creutzfeldt-Jakob disease (CJD).[ncbi.nlm.nih.gov]

  • Subacute Sclerosing Panencephalitis

    Later, high signal changes in deep white matter and severe cerebral atrophy were observed.[doi.org] Soon after, she developed difficulty walking and often talked to a “friend” who was not present.[pediatrics.aappublications.org] This report describes a 5-year-old boy with an atypical feature of SSPE, generalized seizures.[ncbi.nlm.nih.gov]

  • Congenital Muscular Dystrophy

    Apparent diffusion coefficient (ADC) map may reveal increased signal intensity and apparent diffusion coefficient values in the periventricular and deep white matters.[ncbi.nlm.nih.gov] Persons affected with RSMD1 experience difficulty walking due to thigh muscle weakness, spinal rigidity, and mild Achilles tendon tightness.[disabled-world.com] The aim of our study was to evaluate the incidence of seizure in CMD.[ncbi.nlm.nih.gov]

  • Metachromatic Leukodystrophy

    Markers serum/urine arylsulfatase A levels: reduced MRI Characterized by bilateral symmetrical confluent areas of periventricular deep white matter signal change, in particular[radiopaedia.org] Diagnosis is based on the onset of neurological symptoms, presence of gait abnormalities, spasticity, decreased muscle stretch reflexes and neuro-radiological evidence of[ncbi.nlm.nih.gov] Generalized seizures are more frequent in patients with late infantile-onset, whereas partial seizures are more common in those with juvenile-onset disease.[ncbi.nlm.nih.gov]

  • CADASIL Syndrome

    MR imaging lesion load correlated with some clinical features including stroke and dementia, whereas depression is more common in individuals with deep white matter changes[ajnr.org] This can result in an unsteady and wide based gait or sometimes an abnormal gait due to small steps. Should antiplatelet agents such as Aspirin be prescribed in CADASIL?[cambridgestroke.com] Most patients develop seizures (epilepsy) late in the illness that are easy to control.[cadasil.weebly.com]

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