Create issue ticket

3,129 Possible Causes for Abnormal Gait, 'Eye of the Tiger' Sign on MRI, Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)

Did you mean: Abnormal Gait, 'Eye of the Tiger' Sign on MRI, Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical

  • Hallervorden-Spatz Syndrome

    The early onset childhood group had uniform presentation with developmental delay, recurrent falls, gait abnormalities, cognitive deterioration and dystonia.[ncbi.nlm.nih.gov] Iron deposition in conjunction with destruction of the globus pallidus gives rise to the characteristic eye-of-the-tiger sign in MRI.[ncbi.nlm.nih.gov] Usually presents with gait abnormalities. Leads to loss of ambulation within 10-15 years of onset. Extrapyramidal signs including dystonia and rigidity.[genetics4medics.com]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Aromatic L-Amino Acid Decarboxylase Deficiency

    Common symptoms include an uncoordinated or clumsy manner of walking (abnormal gait) and dystonia.[rarediseases.org] […] of the tigersign on MRI.[invitae.com] Children with the moderate form of tyrosine hydroxylase deficiency have an abnormal manner of walking (abnormal gait), dystonic posturing especially when walking, and a tendency[rarediseases.org]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    MPAN commonly begins with difficulty walking.[ghr.nlm.nih.gov] None of our pa-tients exhibited the eye of the tiger sign on T2-weighted MRI.[docslide.net] The present case did not show most of pathognomonic features of the syndrome including loss of acquired purposeful hand skill and language, gait abnormalities and stereotypic[omicsonline.org]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Juvenile Paralysis Agitans of Hunt

    Parkinson described the characteristic rigidity, tremor, hypokinesia and abnormalities of gait and posture in 3 of his own patients and 3 other individuals he had seen on[biotechnologyforums.com] Parkinsonismo precoce associado a lesões palidais de tipo "eye-of-the-tiger" "Eye-of-the-tiger" sign at MRI in a patient with early-onset parkinsonism Egberto Reis Barbosa[scielo.br] gait neurological/behavioral: anomalies in motor capabilities, coordination, and movement 008129 Unknown Bhrd bad hair day skin and hair 006157 Unknown baw black and white[jax.org]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Acute Cerebellar Ataxia

    walking Speech disturbances with slurred speech and changes in tone, pitch, and volume Visual complaints Abnormal eye movements Headache Nausea and vomiting Lightheadedness[cookchildrens.org] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] Symptoms associated with acute cerebellar ataxia include: Coordination impairment in arms, legs and torso Unsteady gait Difficulty walking, frequent stumbling Nystagmus (repetitive[topclassactions.com]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Alcoholic Cerebellar Degeneration

    Cerebellar ataxia differs from gait problems due to abnormalities in other parts of the nervous system, such as the abnormal gait seen in Parkinson’s disease, normal pressure[hopkinsmedicine.org] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] If untreated, this syndrome can further cause brain (cerebellum) degeneration, abnormal gait (walking), memory deficits (retrograde amnesia), and difficulty with abstract[encyclopedia.com]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Vitamin B12 Deficiency

    Neurologic signs and symptoms: Numbness—tingling Weakness of legs, arms, trunk Impaired vibration—position sense Abnormal reflexes Unsteady or abnormal gait Balance problems[b12awareness.org] […] or abnormal gait / falls Ataxia (Neurological disorder affecting balance, coordination and speech) Balance problems Difficulty walking Dizziness Restless legs Visual disturbances[b12deficiency.info] A 9-year-old boy presented with knuckle hyperpigmentation and oral ulcers for 3 years, pallor and easy fatigability for 6 months, gait abnormalities for 3 months, and abnormal[ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Acute Alcohol Intoxication

    walking Blurred vision Slurred speech Pain is dulled Stupor Cannot stand or walk Vomiting Unconsciousness is possible Decreased response to stimuli Apathetic Coma Unconscious[casapalmera.com] […] skills are lacking Excitement Senses are dulled Poor coordination Drowsy Beginnings of erratic behavior Slow reaction time Impaired judgment Confusion Exaggerated emotions Difficulty[casapalmera.com]

    Missing: 'Eye of the Tiger' Sign on MRI Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • Senile Chorea

    It can also lead to: frequently dropping or spilling items abnormal gait muscle weakness slurred speech diminished muscle tone People with this chorea type often display milkmaid[healthline.com] Her MRI did not show the typical “eye of the tigersign or pronounced low signal in the globus pallidus without the additional inserted bright signal that has now been well[jnnp.bmj.com] See the Abnormal Gaits Page for description and demonstration of the Choriform gate.[stanfordmedicine25.stanford.edu]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)
  • COASY Protein-Associated Neurodegeneration

    walking Difficulty in walking 0002355 Dysarthria Difficulty articulating speech 0001260 Eye of the tiger anomaly of globus pallidus 0002454 Obsessive-compulsive behavior[rarediseases.info.nih.gov] MRI and CT " Eye of the tiger sign " on T2 MRI (like PKAN ) associated with bilateral basal ganglia calcifications . Promoted articles (advertising)[radiopaedia.org] For example, there is now evidence that someone in the PSP age group with gradually progressive gait freezing for several years and a normal MRI, even without other abnormalities[psp-blog.org]

    Missing: Increased Urinary Dopamine and Dopamine Metabolites (Paradoxical)

Similar symptoms