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89 Possible Causes for Abnormal Gait, Nocturnal Leg Cramp, Paresthesia

  • Peripheral Neuropathy

    Peripheral neuropathy (PN) is a significant public health concern, resulting in abnormal gait biomechanics, diminished postural stability, and increased risk of falls.[ncbi.nlm.nih.gov] Chemotherapy-induced peripheral neuropathy is a debilitating side effect of chemotherapy, which manifests as paresthesias, dysesthesias, and numbness in the hands and feet[ncbi.nlm.nih.gov] Motor nerve damage can lead to muscle weakness, difficulty walking or moving the arms, cramps and spasms.[foundationforpn.org]

  • Pernicious Anemia

    Neurological symptoms may include muscular weakness and abnormal gait.[orpha.net] The most common of these are paresthesias, weakness, clumsiness, and an unsteady gait.[web.archive.org] Symptoms may include: Abnormal paleness or lack of color of the skin Decreased appetite Irritability Lack of energy or tiring easily (fatigue) Diarrhea Difficulty walking[stanfordchildrens.org]

  • Amyotrophic Lateral Sclerosis

    He had difficulty walking due to poor movement of his right leg, and was diagnosed as having Parkinson's disease because of akinesia.[ncbi.nlm.nih.gov] FDA bans quinine for nocturnal leg cramps. Drug Utilization Rev. 1995; Oct:150. 26. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M.[aafp.org] In 1994, his 46-year-old wife noted motor weakness with paresthesia in the lower limbs.[dx.doi.org]

  • Insulinoma

    The patient reported occasional episodes of weakness, sweating, pallor, tremor, confusion, paresthesias, and visual blurring in the previous year.[journals.lww.com] […] hypoglycemia: neurogenic vs. neuroglycopenic Palpitations Fatigue Diaphoresis Personality change Tremulousness Difficulty with speech or concentration Anxiety Irritability Paresthesias[ijpeonline.biomedcentral.com]

  • Alcoholic Neuropathy

    Neuropathy can not only cause changes in sensation/pain, but can also cause weekness and difficulty walking due to these changes. All bad stuff.[sci.rutgers.edu] Depending on the level of nerve damage in diabetic and alcoholic neuropathy (polyneuropathy) damage sensitivity (numbness, tingling, burning, and "goose"), pain and muscle[minclinic.ru] Other possible symptoms include loss of balance; loss of coordination; difficulty walking; trouble speaking or understanding speech; and vision problems.[livestrong.com]

  • Chronic Alcoholism

    Brain damage Alcohol is associated with blurred vision, memory lapses, slurred speech, difficulty walking and slowed reaction time.[medicalnewstoday.com] People suffering from alcoholic neuropathy may feel burning and tingling sensations in their feet, which may persist or may last from a few months to a few years.[foundationforpn.org] Wernicke's syndrome results in disordered eye movements, very poor balance, and difficulty walking.[medical-dictionary.thefreedictionary.com]

  • Restless Legs Syndrome

    gait analysis in restless legs syndrome: A preliminary report in 13 patients, Sleep Medicine, 10, 3, (312), (2009).[doi.org] Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org] As reported by patients, paresthesia and/or dysesthesia may range in severity from slightly unpleasant to extremely agonizing.[symptoma.com]

  • Parkinson's Disease

    […] disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hyperreflexia Increased reflexes[rarediseases.info.nih.gov] , glabellar reflexes), non-motor symptoms (eg, autonomic dysfunction, cognitive/neurobehavioral abnormalities, sleep disorders and sensory abnormalities such as anosmia, paresthesias[ncbi.nlm.nih.gov] […] been documented or the patient has not had an adequate trial of levodopa or a dopamine agonist Sensory abnormalities Sensory symptoms such as olfactory dysfunction, pain, paresthesia[doi.org]

  • Peripheral Vascular Disease

    walking, loss of balance or coordination Sudden severe headache with no known cause Do not try to "wait it out" at home.[webmd.com] Additional conditions to consider are acute embolism, deep or superficial venous thrombosis, restless legs syndrome, systemic vasculitides, nocturnal leg cramps, muscle or[aafp.org] Pentoxifylline 800 mg/d was found to be effective in improving the symptoms in patients with noninsulin-dependent diabetes mellitus, including improvement in walking distance, paresthesia[ncbi.nlm.nih.gov]

  • Spinal Cord Lesion

    walking or balancing; difficulty breathing after the injury; or a twisted neck or back.[livescience.com] Specific symptoms depend on the site of injury. e.g. posterior horn or column injury produces paresthesias, pain and other sensory disturbances; anterior horn or corticospinal[kobiljak.msu.edu] The symptomatology (symptoms and signs) of spinal cord compression consists of sensory (pain, numbness and paresthesia), motor and autonomic disturbances, the nature and extend[neuroanatomy.wisc.edu]

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