Create issue ticket

43 Possible Causes for Abnormal Gait, Onset of Symptoms in First or Second Decade of Life, Psychomotor Retardation

  • Hallervorden-Spatz Syndrome

    There is an early onset classic form with symptoms of extrapyramidal disease beginning in the first decade of life and rapid progression to loss of ambulation in about 15[disorders.eyes.arizona.edu] The early onset childhood group had uniform presentation with developmental delay, recurrent falls, gait abnormalities, cognitive deterioration and dystonia.[ncbi.nlm.nih.gov] Usually presents with gait abnormalities. Leads to loss of ambulation within 10-15 years of onset. Extrapyramidal signs including dystonia and rigidity.[genetics4medics.com]

  • Young Adult-Onset Distal Hereditary Motor Neuropathy

    Age of onset is in the second and third decades of life and rarely in the first. Recovery is usually complete and begins weeks to months after the onset of symptoms.[emedicine.medscape.com] gait.[now.aapmr.org] retardation Oculoauriculofrontonasal syndrome Arts syndrome Erythropoietic protoporphyria Fuhrmann syndrome Mastocytosis cutaneous with short stature conductive hearing loss[checkrare.com]

  • Hereditary Spastic Paraplegia

    Clinical Correlations: Spastic paraplegia 7 may have its onset in the second decade of life but sometimes much later.[disorders.eyes.arizona.edu] HSP is a heterogeneous group of neurodegenerative disorders with progressive lower limb spasticity and weakness leading to abnormal gait as the principal clinical feature.[omicsonline.org] Retardation and Characteristic Facies 2 AR 616801 Mast Syndrome AR 248900 Mental Retardation, X-Linked, Syndromic, Claes-Jensen Type XL 300534 Neuropathy, Hereditary Sensory[preventiongenetics.com]

  • Huntington's Disease

    However, in some families a juvenile form of HD has been seen with an onset of symptoms in the first or second decades of life.[encyclopedia.com] Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com] All psychomotor processes become severely retarded. Patients experience psychiatric symptoms and cognitive decline.[ncbi.nlm.nih.gov]

  • Friedreich Ataxia

    Most affected people become wheelchair dependent by the second or third decade of life.[web.archive.org] Related Cases Disease: Friedreich’s Ataxia Degenerative Nerve Diseases Symptom/Presentation: Ataxia, Dizziness, and Vertigo Abnormal Gait Specialty: Genetics Medical History[pediatriceducation.org] […] and dysequlibrium syndrome CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES Cerebellar Atrophy, Visual Impairment, and Psychomotor Retardation Charlevoix-Saguenay spastic[rgd.mcw.edu]

  • Congenital Muscular Dystrophy

    The onset of symptoms usually occurs in the first or second decade of life. Affected individuals usually present with impairment of upper extremity elevation.[icd10data.com] Persons affected with RSMD1 experience difficulty walking due to thigh muscle weakness, spinal rigidity, and mild Achilles tendon tightness.[disabled-world.com] We describe a 5-year-old girl with psychomotor retardation, ataxia, spasticity, muscle weakness and increased serum creatine kinase levels.[ncbi.nlm.nih.gov]

  • Spastic Paraplegia

    Clinical Correlations: Spastic paraplegia 7 may have its onset in the second decade of life but sometimes much later.[disorders.eyes.arizona.edu] PATIENTS CONCERNS: A 12-year-old boy presented as ankle sprained, lower limb stiffness, abnormal gait since he was 5 years old.[ncbi.nlm.nih.gov] Retardation and Characteristic Facies 2 AR 616801 Mast Syndrome AR 248900 Mental Retardation, X-Linked, Syndromic, Claes-Jensen Type XL 300534 Neuropathy, Hereditary Sensory[preventiongenetics.com]

  • Spastic Paraparesis-Deafness Syndrome

    Clinical Correlations: Spastic paraplegia 7 may have its onset in the second decade of life but sometimes much later.[disorders.eyes.arizona.edu] Showing of 16 80%-99% of people have these symptoms Gait disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Hemiplegia/hemiparesis Paralysis or weakness[rarediseases.info.nih.gov] retardation with or without seizures AR 13 13 HSPD1 * Spastic paraplegia, Leukodystrophy, hypomyelinating AD/AR 5 5 IBA57 Multiple mitochondrial dysfunctions syndrome 3,[blueprintgenetics.com]

  • Autosomal Dominant Spastic Paraplegia Type 42

    onset, usually within the first or second decades of life.[jamanetwork.com] The father, brother, and uncle were both asymptomatic while the grandfather was wheelchairbound and the mother had abnormal gait.[omicsonline.org] CCHLND is an autosomal recessive disorder characterized by congenital cataracts, severe psychomotor retardation, and hearing loss associated with decreased serum ceruloplasmin[slc.bioparadigms.org]

  • Proximal Myopathy with Extrapyramidal Signs

    The prognosis is most favorable when the onset of symptoms occurs after the second decade of life.[intranet.tdmu.edu.ua] Difficulty walking in a straight line. Broad-based posture. Assessment should include asking the patient to walk heel-to-toe.[patient.info] A subacute form begins during early childhood with vomiting, hypotonia, growth and psychomotor retardation.[pliem.co.za]

Similar symptoms