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3,046 Possible Causes for Abnormal Gait, Progressive Disease

  • Primary Progressive Multiple Sclerosis

    A key symptom associated with PPMS is difficulty walking. This may result from the damage to the spinal cord that occurs with PPMS.[medicalnewstoday.com] The majority of patients starts with relapsing remitting (RR) disease; approximately 50-60% of these patients progress to secondary progressive (SP) disease.[ncbi.nlm.nih.gov] People with PPMS may have trouble with balance and coordination or have difficulty walking.[healthline.com]

  • Lafora Disease

    Lafora disease causes seizures, muscle spasms, difficulty walking, dementia, and eventually death.[diseaseinfosearch.org] Daily living activities and social interaction were preserved in all cases and, overall, the progression of the disease was slow.[ncbi.nlm.nih.gov] About Lafora Disease Lafora Disease (LD) is a rare, progressive, autosomal recessive neurodegenerative disorder characterized by intractable seizures, difficulty walking,[prnewswire.com]

  • Progressive Supranuclear Palsy

    Gait abnormality, severe upward gaze palsy, bilateral bradykinesia and absence of alien limb syndorme separated PSP from corticobasal degeneration.[doi.org] The current gold standard for measuring clinical disease progression in PSP is the PSP Rating Scale score.[ncbi.nlm.nih.gov] There are features of PSP that are likely to contribute to gait abnormalities.[bmcneurol.biomedcentral.com]

  • Amyotrophic Lateral Sclerosis

    He had difficulty walking due to poor movement of his right leg, and was diagnosed as having Parkinson's disease because of akinesia.[ncbi.nlm.nih.gov] This review examined current research related to moderate exercise for maintaining independence without accelerating disease progression in persons with ALS.[ncbi.nlm.nih.gov] walking or doing your normal daily activities Difficulty holding your head up or keeping good posture Muscle cramps and twitching in your arms, shoulders and tongue Eventually[disabled-world.com]

  • Alzheimer Disease

    gait.[ncbi.nlm.nih.gov] BACKGROUND AND OBJECTIVE: Semantic memory measures may be useful in tracking and predicting progression of Alzheimer disease.[ncbi.nlm.nih.gov] Alzheimer’s is a progressive disease. This means that gradually, over time, more parts of the brain are damaged.[alzheimers.org.uk]

  • Binswanger Disease

    The abnormality of gait that may occur in patients with subcortical arteriosclerotic encephalopathy is described in 12 patients in whom difficulty walking was the presenting[medigoo.com] Language rus PubMed ID 4074151 TY - JOUR T1 - [Progressive subcortical arteriosclerotic encephalopathy (Binswanger's disease)].[unboundmedicine.com] Extrapyramidal disease Gait disturbance Low back pain Progressive encephalopathy Pseudobulbar signs Rigidity Abnormality of the skeletal system Low back pain Congenital anomaly[familydiagnosis.com]

  • Duchenne Muscular Dystrophy

    walking.[orthobullets.com] As with DMD, speed of disease progression in GRMD varies substantially.[ncbi.nlm.nih.gov] DMD symptoms may include: difficulty walking a loss of ability to walk enlarged calves learning disabilities, which occurs in about one-third of affected individuals a lack[healthline.com]

  • Parkinson's Disease

    […] disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Hallucinations Hallucination Sensory hallucination [ more ] 0000738 Hyperreflexia Increased reflexes[rarediseases.info.nih.gov] This study assessed the effect of levodopa on the rate of progression of Parkinson's disease.[ncbi.nlm.nih.gov] Slower progression of Parkinson's disease with ropinirole versus levodopa: the REAL-PET study.[nejm.org]

  • Parkinson's Disease Type 3

    The advanced stage is marked by rapid and involuntary rhythmic movements, twisting postures, contortions of the torso, abnormal gait and, ultimately, fixed postural deformities[aans.org] However, symptoms vary and may worsen as the disease progresses.[healthline.com] Understanding Parkinson's Symptoms Some people with Parkinson’s will first notice a sense of weakness, difficulty walking, and stiff muscles.[webmd.com]

  • Huntington's Disease

    Gait abnormalities: Gait abnormalities start developing in the intermediate stage of the disease. The gait is irregular and unsteady.[symptoma.com] HD is a progressive disease; this means that it gets worse over time, and coordination of everyday activities become harder and harder.[my.clevelandclinic.org] He had depression, poor cognitive function, choreiform movements, difficulty pronouncing words, and difficulty walking.[ncbi.nlm.nih.gov]

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