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36 Possible Causes for Abnormal Hypothalamo-Pituitary Axis

  • Endogenous Depression

    In contrast to the previously reported hypothalamo-pituitary-adrenal cortical and thyroid axis abnormalities in these patients, our findings suggest that PRL secretion was[ncbi.nlm.nih.gov] The results of this study suggest that, in contrast to the hypothalamo-pituitary-adrenal cortical and thyroid axis abnormalities frequently found in endogenous depressives[ncbi.nlm.nih.gov]

  • Hypogonadism

    All of our patients had a metyrapone test performed to assess the integrity of their hypothalamo-pituitary-adrenal axis, and all were normal, as were prolactin levels.[academic.oup.com] Thyroid function tests were performed in all patients at diagnosis, and no patient had abnormalities in thyroid function testing suggestive of pituitary disease.[academic.oup.com]

  • Dysthymic Disorder

    Abnormalities in neuroendocrine systems, especially thyroid and hypothalamo-pituitary-adrenocortical (HPA) systems, have been linked to depressive disorders in general, although[emedicine.medscape.com] […] the HPA axis has not been adequately studied in dysthymic disorder.[emedicine.medscape.com]

  • Hemochromatosis

    All of our patients had a metyrapone test performed to assess the integrity of their hypothalamo-pituitary-adrenal axis, and all were normal, as were prolactin levels.[academic.oup.com] Thyroid function tests were performed in all patients at diagnosis, and no patient had abnormalities in thyroid function testing suggestive of pituitary disease.[academic.oup.com]

  • Fibromyalgia

    Hypothalamo-Pituitary-Adrenal Axis There is substantial data supporting an abnormal function of the HPA axis in fibromyalgia.[ncbi.nlm.nih.gov]

  • Zinc Deficiency

    Abstract Dietary zinc deficiency increases glucocorticoid secretion from the adrenal cortex via enhanced hypothalamo-pituitary-adrenocortical (HPA) axis activity and induces[ncbi.nlm.nih.gov] […] neuropsychological symptoms, i.e., behavioral abnormality.[ncbi.nlm.nih.gov]

  • Cushing Syndrome

    Abnormal hypothalamic-pituitary-adrenal function in anorexia nervosa. N Engl J Med. 1986;3141335- 1342 Google Scholar Crossref 66.[jamanetwork.com] Harbuz MSLightman SL Stress and the hypothalamo-pituitary adrenal axis. J Endocrinol. 1992;134327- 339 Google Scholar Crossref 67.[jamanetwork.com]

  • Growth Hormone Deficiency

    pituitary stalk. 24 Other abnormalities associated with GHD include hypothalamo-pituitary axis tumours such as craniopharyngioma, septo-optic dysplasia, corpus callosum hypoplasia[adc.bmj.com] […] within the hypothalamo-pituitary axis provides powerful supporting evidence for a diagnosis of GHD.[adc.bmj.com] The most common radiological finding in GHD children is a variable combination of an ectopic posterior pituitary gland, anterior pituitary hypoplasia and a thin or interrupted[adc.bmj.com]

  • Pituitary Dwarfism

    Abnormalities of the hypothalamo-hypophyseal axis are frequently associated with pituitary deficiency.[ncbi.nlm.nih.gov]

  • Hypogonadotropic Hypogonadism Type 18

    The suboptimal sperm counts seen in a few patients probably reflect previous abnormal activation of the hypothalamopituitary–gonadal axis during early infancy, a period critical[nejm.org] Furthermore, the postreversal neuroendocrine profiles demonstrated activation of the hypothalamopituitary–gonadal axis in adulthood.[nejm.org] […] of the hypothalamopituitary axis. 1 Idiopathic hypogonadotropic hypogonadism is caused by an isolated defect in gonadotropin-releasing hormone (GnRH) release, action, or[nejm.org]

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