Abnormal Nerve Conduction: Causes & Reasons

Possible Causes for Abnormal Nerve Conduction

Consistent with this view is the finding of glycogen accumulation in peripheral nerves, abnormal nerve conduction velocities, and “neuropathic” features by EMG. [nature.com]

Electromyography (EMG) reveals a widespread myopathy; nerve conduction studies may also be abnormal. 28, 29 Individuals with GSD III may be at increased risk for osteoporosis [nature.com]

nerve conduction studies (NCSs), whereas approximately 90% of patients with EIKD have abnormal brainstem auditory evoked responses (BAER), 65% have an abnormal electroencephalogram [dx.doi.org]

Spinocerebellar Ataxia Type 10

Brain magnetic resonance imaging showed predominant cerebellar atrophy, and nerve conduction studies indicated polyneuropathy in 66% of patients. [ncbi.nlm.nih.gov]

One family showed hepatic, cardiac, and hematological abnormalities in affected members. [ncbi.nlm.nih.gov]

Spinocerebellar Ataxia with Rigidity and Peripheral Neuropathy

Nerve conduction studies were done which did not record bilaterally any compound motor and sensory potential over the distribution of peroneal nerve. [casereports.in]

Needle EMG showed chronic neurogenic changes in all but one cases with abnormal nerve conduction studies. [jnnp.bmj.com]

[…] findings Abnormal findings on motor and sensory nerve conduction studies Cerebellar atrophy and a thin spinal cord on MRI Evidence of iron accumulation within mitochondria [emedicine.medscape.com]

Hereditary Areflexic Dystasia

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

Charcot-Marie-Tooth Disease Type 2S

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

There are different categories of CMT, depending on what symptoms the disease presents with, the pattern of abnormalities on nerve conduction studies, the manner in which [hnf-cure.org]

Hmsn i is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in hmsn ii. [icd10data.com]

Median Neuropathy

Nerve conduction slowing across the carpal tunnel may be associated with metabolic abnormalities under hyperglycemia. [ncbi.nlm.nih.gov]

Assessment of nerve conduction abnormalities across the carpal tunnel is difficult in patients with DPN, because MN and DPN might affect median nerve conduction in a similar [ncbi.nlm.nih.gov]

Median motor distal latencies were prolonged in 38%, and median sensory nerve conduction velocities were slowed in 40%. [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 2R

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

Charcot-Marie-Tooth Disease Type 2J

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

Mitochondrial Complex 1 Deficiency Nuclear Type 25

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 5 Deficiency Mitochondrial Type 1

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Charcot-Marie-Tooth Disease Type 2B2

Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Decreased motor nerve conduction velocity Distal [ncbi.nlm.nih.gov]

[…] of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Decreased motor nerve conduction velocity Distal sensory [ncbi.nlm.nih.gov]

They may cause axon degeneration, or they may simply cause axons to malfunction.[1] The myelin sheath allows nerve cells to conduct signals faster. [en.wikipedia.org]

Isaac Syndrome

EMG studies, which show characteristic abnormalities; these abnormalities include after-discharges on nerve conduction studies and, on needle EMG studies, fasciculation potentials [msdmanuals.com]

Clinical evaluation Results of nerve conduction and EMG studies The diagnosis of Isaacs syndrome is based on the above clinical findings and results of nerve conduction and [msdmanuals.com]

[…] intermittent cramps, increased sweating, and pseudomyotonia (impaired relaxation after a strong muscle contraction but without the typical waxing-and-waning electromyography [EMG] abnormality [msdmanuals.com]

Charcot-Marie-Tooth Disease Type 4B3

CMT can be diagnosed based on clinical examinations, electromyography to measure nerve conduction velocities and nerve biopsies to identify abnormal myelination. [cags.org.ae]

Abnormality of the nervous system Areflexia Brain atrophy Decreased nerve conduction velocity Distal sensory impairment Gait disturbance Intellectual disability Onion bulb [ncbi.nlm.nih.gov]

Nerve conduction velocities are markedly reduced and nerve biopsies may show depleted myelinated axons or focally folded myelin. [cags.org.ae]

Mitochondrial Complex 1 Deficiency Nuclear Type 33

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type 12

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Charcot-Marie-Tooth Disease Type 4G

[…] of the nervous system Axonal regeneration Decreased motor nerve conduction velocity Decreased number of large peripheral myelinated nerve fibers Hyporeflexia Paralysis Peripheral [ncbi.nlm.nih.gov]

Decreased nerve conduction velocity Decreased NCV, Reduced nerve conduction velocities, Delayed nerve conduction velocity, Slow nerve conduction velocity, Slowed nerve conduction [rarediseases.oscar.ncsu.edu]

Abnormality of limbs Abnormal foot morphology Abnormality of the hand Abnormality of the musculoskeletal system Difficulty walking Distal muscle weakness Scoliosis Abnormality [ncbi.nlm.nih.gov]

Asymmetric Motor Neuropathy

Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies. [thieme-connect.com]

Conduction abnormalities induced by sera of patients with multifocal motor neuropathy and anti-GM1 antibodies. Muscle Nerve 1993;16(6):610–615. [springermedizin.de]

Hereditary Motor and Sensory Neuropathy Type 5

conduction velocities. [orpha.net]

Additional variable features may include proximal muscle weakness, abnormal gait, arthrogryposis, scoliosis, cognitive impairment, and spasticity. [orpha.net]

[…] progressive, predominantly distal, lower limb muscle weakness and atrophy, delayed motor development, variable sensory loss, and pes cavus in the presence of normal or near-normal nerve [orpha.net]

Mitochondrial Complex 1 Deficiency Nuclear Type 18

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type 7

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type26

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type 8

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type 27

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Cowchock Syndrome

Motor nerve conduction velocities range from normal to moderately delayed, while sensory nerve conduction velocities are markedly abnormal. A sural nerve biopsy ... [accesspediatrics.mhmedical.com]

Only males are affected, whereas female carriers show only minor abnormalities in sensory nerve conduction, electromyography, and hearing. [accesspediatrics.mhmedical.com]

Ulnar Nerve Disorder

Ulnar nerve conduction velocity-effect of elbow position on measurement. Arch Phys Med Rehabil 1971; 53: 362. [ Links ] 26. [scielo.org.pe]

Ulnar neuropathy with normal electrodiagnosis and abnormal nerve ultrasound. Arch Phys Med Rehabil. 2010; 91(2): 318-320. [ Links ] 27. Bismil QMK, Bismil MSK. [scielo.org.pe]

Cubital tunnel syndrome with false-negative nerve conduction studies treated with wide awake ulnar nerve decompression via the OSWA pathway. [scielo.org.pe]

Mitochondrial DNA Depletion Syndrome Type 8

nerve conduction as well as analysis of mitochondria from liver, intestines, muscle, and nerve tissue can also be used to support the diagnosis.[2][4] Management[edit] A [en.wikipedia.org]

[…] duodenum, diverticula, and white matter changes are required to confirm the diagnosis.[4] Elevated blood and urine nucleoside levels are also indicative of MNGIE syndrome.[2] Abnormal [en.wikipedia.org]

Charcot-Marie-Tooth Disease Type 2B1

[…] of the nervous system Areflexia Axonal degeneration/regeneration Decreased motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory [ncbi.nlm.nih.gov]

Proximal muscle weakness Abnormality of the nervous system Areflexia Axonal degeneration/regeneration Decreased motor nerve conduction velocity Decreased number of peripheral [ncbi.nlm.nih.gov]

Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Foot dorsiflexor weakness Kyphoscoliosis Proximal muscle weakness Upper limb muscle weakness Abnormality [ncbi.nlm.nih.gov]

Mitochondrial Complex 1 Deficiency Nuclear Type 23

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Mitochondrial Complex 1 Deficiency Nuclear Type 19

Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol. 2006;63(5):746-8. [ Links ] 27. [scielo.org.pe]

Charcot-Marie-Tooth Disease Type 4D

[…] potentials Areflexia Axonal loss Decreased nerve conduction velocity Distal sensory impairment Gait disturbance Hyporeflexia Onion bulb formation Segmental peripheral demyelination [ncbi.nlm.nih.gov]

[…] of visual evoked potentials Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Abnormal auditory evoked [ncbi.nlm.nih.gov]

Intraaxonal accumulation of curvilinear autofluorescent lipopigment storage material Abnormality of limbs Abnormality of the hand Talipes cavus equinovarus Abnormality of the eye Abnormality [ncbi.nlm.nih.gov]