Possible Causes for abnormal renal function Renal Function Impairment […] are abnormal in up to 30% of HIV-infected patients. 4 AIDS-related kidney disease has become a common cause of end stage renal disease (ESRD) requiring dialysis 4, and kidney [myhivclinic.org] Both have low urine concentrations and are not indicated in the treatment of UTI in patients with normal or abnormal renal function. [cjasn.asnjournals.org] Background There is a high prevalence (30%) of abnormal renal function among patients with HIV disease. [hiv.va.gov] Chronic Kidney Insufficiency Neither of these studies addressed whether the ARF (or AKI) occurred against a background of normal or abnormal renal function. [cjasn.asnjournals.org] Impairment of health or a condition of abnormal functioning of the kidney. Impairment of the renal function due to chronic kidney damage. [icd10data.com] Initially, as renal tissue loses function, there are few noticeable abnormalities because the remaining tissue increases its performance (renal functional adaptation). [merckmanuals.com] Acute Kidney Injury Our study showed a reference GFR higher in G1/G2 than in G3/G4 [79 22 and 63 21 mL/min per 1.73 m 2, p 0.03], and an abnormal baseline renal function was associated with [journals.plos.org] abnormalities. [news-medical.net] Some patients who survive acute renal failure and the drug overdose may still fail to regain full functionality of the kidneys, according to MayoClinic.com. [livestrong.com] Diabetic Nephropathy DN is considered the case when there is macroalbuminuria alone or macroalbuminuria together with abnormal renal function. [news-medical.net] Hyperfiltration, an early functional abnormality, is only a relative predictor for the development of renal failure. [merckmanuals.com] Other urinary tract abnormalities commonly occurring with diabetic nephropathy that may accelerate the decline of renal function include papillary necrosis, type IV renal [msdmanuals.com] Preeclampsia Other renal function tests such as serum creatinine and creatinine clearance are abnormal in 50% to 70% of the cases. 62 Hemoconcentration and increased blood viscosity are [glowm.com] Hypertension and proteinuria are not the only nor necessarily the most important signs of preeclampsia. 1 19 Renal function tests, thrombocytopenia, and abnormal plasma concentrations [bmj.com] As a result, women with severe preeclampsia, particularly those with abnormal renal function, those with capillary leak, and those with early onset are at increased risk for [glowm.com] Acute Pyelonephritis Recovery of renal function may occur if antibiotics are promptly instituted. Renal size generally decreases after recovery. [ncbi.nlm.nih.gov] – Criteria for hospital admission: • Patients at risk of complications: children, pregnant women, men1, functional or structural abnormality of the urinary tract (lithiasis [medicalguidelines.msf.org] Impaired renal function or renal damage potentially leading to acute kidney injury or chronic kidney disease (CKD). [patient.info] Tumor Lysis Syndrome Tumour lysis syndrome is associated with high levels of uric acid, phosphate and potassium along with low levels of calcium and abnormal renal function. [ncbi.nlm.nih.gov] Function tests, Serum Calcium, Serum Phosphate, serum Uric Acid ) Manage electrolyte abnormalities See Hyperkalemia Management See Hypocalcemia See Hyperuricemia See Hyperphosphatemia [fpnotebook.com] Function tests, Serum Calcium, Serum Phosphate, serum Uric Acid) Manage electrolyte abnormalities See Hyperkalemia Management See Hypocalcemia See Hyperuricemia See Hyperphosphatemia [fpnotebook.com] Acute Renal Failure with Oliguria […] liver function test (hepatic function abnormal, hyperbilirubinaemia) h Hepatotoxicity (drug-induced liver injury, hepatitis cholestatic, hepatocellular injury, hepatotoxicity [mymemory.translated.net] […] in renal and tubular function.. [anesthesiology.pubs.asahq.org] Tubular function abnormalities precede a decline in the glomerular filtration rate. [elsevier.es] Non-Oliguric Renal Failure Tubular function abnormalities precede a decline in the glomerular filtration rate. [elsevier.es] Pathologically all renal structures are involved but interstitial nephritis is the basic lesion of leptospirosis. Glomerular changes are usually not remarkable. [elsevier.es] AKI can manifest after several days of illness in oliguric or non-oliguric form, with serum electrolyte abnormalities reflecting proximal renal tubular dysfunction. [elsevier.es] Vasculitis […] urine analysis and/or impaired renal function (glomerular filtration rate of 50% normal for age) Testicular pain or tenderness Signs or symptoms suggesting vasculitis of [emedicine.medscape.com] These abnormalities resolved within 1 year in 8 of these children, whereas in the other 2 children the urinary findings persisted without decline in renal function. [lupusinternational.com] […] subcutaneous nodules, other vasculitic lesions) Myalgia or muscle tenderness Systemic hypertension, relative to childhood normative data Mononeuropathy or polyneuropathy Abnormal [emedicine.medscape.com] Glomerulonephritis These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. [fpnotebook.com] […] in renal function or urinary sediment. [revistanefrologia.com] Definition (MSH) Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement [fpnotebook.com] Hydronephrosis Prognosis with hydronephrosis depends upon the type of obstruction, degree of remaining renal function, and the presence of other abnormalities or genetic syndromes. [columbiaobgyn.org] […] asymmetry 1 cm abnormal renal parenchyma severe VUR (Gr IV-V) reduced renal function increasing hydronephrosis grade or renal pelvis dilatation (RPD) 50 per cent increase [bettersafercare.vic.gov.au] Intraluminal obstruction: calculi, sloughed renal papillae, blood clot, fungal ball Intrinsic abnormality of the urinary collecting system: transitional cell carcinomas, benign [unboundmedicine.com] Chronic Pyelonephritis Nevertheless, in one third of cases the radionuclide studies demonstrated certain abnormalities more readily, including focal parenchymal damage, renal functional impairment [ncbi.nlm.nih.gov] renal function in the foetus. 8 Generally speaking, sodium and chlorine concentrations higher than 90 mEq/L and osmolalities below 210 mOsm/kg H2O in amniotic fluid suggest [analesdepediatria.org] The combination of extensive bilateral renal scarring and proteinuria is associated with the worst renal function. [ncbi.nlm.nih.gov] Renal Cell Carcinoma In view of this, pazopanib appears to represent an alternative for this patient group, as well as individuals with a recent ( Impaired renal function Abnormal renal function [cancertherapyadvisor.com] Renal function and liver function tests were normal. Urine analysis was negative without any hematuria. [cancerjournal.net] Other symptoms of renal cell carcinoma may include high blood pressure (hypertension), anemia, abnormal liver function and fever. [rarediseases.org] Sarcoidosis No usual abnormalities related to MM, such as lytic lesions or renal function impairment, were present at the time of diagnosis, and only the serum protein electrophoresis [hindawi.com] Abnormal calcium metabolism in sarcoidosis can lead to pancreatitis, nephrocalcinosis, nephrolithiasis, impaired renal function, renal failure and death, 11 highlighting the [doi.org] Familial Interstitial Nephritis Renal biopsy of the presented case indicated chronic interstitial nephritis without glomerular basement membrane abnormalities. [ncbi.nlm.nih.gov] Sequential tests in patients with IgG4-related TIN show loss of renal function [4]. [austinpublishinggroup.com] […] leading to end-stage renal disease. gouty nephropathy any of a group of chronic kidney diseases associated with the abnormal production and excretion of uric acid. [medical-dictionary.thefreedictionary.com] Hereditary Renal Cell Carcinoma OBJECTIVE: The purpose of this article is to discuss the histopathologic features, genetics, clinical presentation, and imaging of hereditary renal cancer syndromes. CONCLUSION: Hereditary renal cell carcinoma syndromes can be diagnosed with a pattern-based approach focused on the predominant histologic renal cell[…] [ncbi.nlm.nih.gov] Non-Allergic Interstitial Nephritis Common (1% to 10%): Abnormal renal function Frequency not reported : Interstitial nephritis, renal failure, allergic/non-allergic glomerulonephritis, nephrotic syndrome, [drugs.com] In mild cases, the clinical presentation may consist of subtle tubular function abnormalities, such as Fanconi syndrome (ie, aminoaciduria, glycosuria, renal tubular acidosis [emedicine.medscape.com] The acute reduction in renal function results in both biochemical and clinical abnormalities, related to the inability of the kidney to eliminate water, metabolic by-products [abdominalkey.com] Multiple Myeloma Patients initially presenting with renal failure also do poorly unless kidney function improves with therapy (which typically happens with current treatment options). [msdmanuals.com] In addition, bortezomib clearance is independent of renal function. 92 Diagnostic considerations Patients with symptoms or laboratory abnormalities, which may be attributable [doi.org] Unfavorable prognostic signs at diagnosis are lower serum albumin, higher beta-2 microglobulin levels, elevated LDH levels, and specific cytogenetic abnormalities in the tumor [msdmanuals.com] Renal Papillary Necrosis The procedure cannot help in the assessment of renal function or the renal parenchyma. [emedicine.com] In the early stage, when papillary swelling may be the only abnormal radiologic finding, swelling is difficult to recognize. [emedicine.com] Henoch-Schönlein Purpura […] specialist is recommended if there is: Hypertension Abnormal renal function Macroscopic haematuria for 5 days Nephrotic syndrome Acute nephritic syndrome Persistent proteinuria [rch.org.au] No patients were nephrotic, nephritic or had an abnormal renal function at the initial diagnosis. [ncbi.nlm.nih.gov] […] proteinuria or macroscopic haematuria at any point should prompt paediatric review with investigations (outlined above) and ongoing follow-up based on results Discussion with a Renal [rch.org.au] Renal Pelvis Squamous Cell Carcinoma Acidosis may result in electrolyte abnormalities, osteomalacia, growth retardation, altered sensorium, altered hepatic metabolism, renal calculi, and abnormal drug metabolism [oncohemakey.com] In general, patients with normal renal function as well as normal hepatic function are less prone to acidosis and its complications. [oncohemakey.com] Granulomatosis with Polyangiitis GPA can also affect the eyes, skin, joints and nervous system.37 Renal involvement is characterised by abnormal renal function with red cell casts in urinalysis, and glomerulonephritis [ncbi.nlm.nih.gov] The complete blood count, renal function, electrolytes, thyroid function test, anti –TPO antibody, urine examination did not revealed abnormality. [austinpublishinggroup.com] Results may include the following: Abnormal kidney function tests and urinalysis in patients with renal involvement Rheumatoid factor is positive in a low titer in two thirds [emedicine.medscape.com] Renal Transplant Rejection However, there are several limitations to US including its inability to assess renal function or differentiate the causes of parenchymal abnormalities such as acute rejection [appliedradiology.com] Leiomyosarcoma A leiomyosarcoma is a rare cancerous tumor of the smooth muscle cells. It is most often found in the uterus or abdomen. Goldblum JR, Folpe AL, Weiss SW. Leiomyosarcoma. In: Goldblum JR, Folpe AL, Weiss SW, eds. Enzinger and Weiss's Soft Tissue Tumors. 6th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 17. National[…] [nlm.nih.gov] Nephrotic Syndrome CXR and abdominal or renal ultrasound scan (especially if renal function is abnormal): to check for pleural effusion or ascites, the presence of two kidneys, the size and [patient.info] LeRoy The relationship of hipertensión and renal failure in scleroderma (progresive systemic sclerosis) to structural and functional abnormalities of the renal cortical circulation [reumatologiaclinica.org] […] reduced renal function, and immunological disorders. [patient.info] Minimal Change Nephropathy We have focused on these diseases because podocyte flattening appears to be the primary cause of the functional glomerular abnormalities. [jasn.asnjournals.org] Therefore, we have examined here the expression and distribution of DG directly in human renal biopsies from patients with MCN and FSGS. [jasn.asnjournals.org] Lupus Nephritis Although renal function on baseline was not different between subclasses, IV-G showed lower levels, although not significant, of estimated glomerular filtration based on CKD-EPI [ncbi.nlm.nih.gov] Kidney biopsy is necessary in all patients with Lupus who have abnormal urine and/or reduced renal function. [lupus-support.org.uk] These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. [fpnotebook.com] Hypercalcemic Nephropathy The calcium causes cumulative functional and histological abnormalities that lead to a decreased glomerular filtration rate and kidney failure. hypercalcemic nephropathy Renal [medical-dictionary.thefreedictionary.com] One hundred three patients with normal renal function and no history of taking potassium-depleting drugs comprise the substance of this study. [annals.org] or abnormal liver function studies. [doi.org] Hypovolemic Shock […] dysfunction By virtue of the liver’s role in host defense, the abnormal synthetic functions caused by liver dysfunction can contribute to both the initiation and the progression [emedicine.medscape.com] […] glutamine levels, this may lessen the immune response by decreasing leukocyte and natural killer (NK) cell counts, as well as total B-cell and T-cell counts. [28] Hepatic and renal [emedicine.medscape.com]
