Abnormal Renal Function: Causes & Reasons

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Possible Causes for Abnormal Renal Function

Postrenal Azotemia

"Uremia" is the clinical syndrome that occurs as a result of severe azotemia due to abnormal renal function. • Causes: ◦ Reduced glomerular filtration rate: - Reduced renal [researchonline.jcu.edu.au]

"Uremia" is the clinical syndrome that occurs as a result of severe azotemia due to abnormal renal function. [vetstream.com]

[…] patients with risk factors Advanced age Abnormal renal function or diabetes Volume depletion Recent vascular surgery Recent trauma * Avoid nephrotoxic agents * Apply preventive [enotes.tripod.com]

Congenital Hydronephrosis

These infants were divided into two groups on the basis of renal status: (1) abnormal renal function and/or surgery required (n = 31) and (2) normal renal function with no [ncbi.nlm.nih.gov]

None had abnormalities of the bladder or contralateral kidney. Differential renal function greater than 55% was defined as supranormal. [ncbi.nlm.nih.gov]

Most people lead normal, healthy lives with one functioning kidney. Renal Hypoplasia In renal hypoplasia, one or both kidneys are abnormally small. [nyulangone.org]

Hyporeninemic Hypoaldosteronism

Despite only mildly abnormal renal function, serum K+ was elevated to 6.2 meq/L, and plasma renin activity (0.12 ng/mL h) and aldosterone (4.4 ng/dL) failed to respond to [ncbi.nlm.nih.gov]

Despite only mildly abnormal renal function, serum K + was elevated to 6.2 meq/L, and plasma renin activity (0.12 ng/mL h) and aldosterone (4.4 ng/ dL) failed to respond to [annals.org]

A chronic decline in renal function is associated with abnormalities of Ca, phosphorus, parathyroid hormone (PTH), and vitamin D metabolism. [163.178.103.176]

Renal Tubular Dysfunction

The abnormalities of blood chemistry and renal tubular function disappeared after four weeks of abstinence. [ncbi.nlm.nih.gov]

OBJECTIVE: To define the renal tubular functional abnormalities in patients with cystic disease of the kidneys. [ncbi.nlm.nih.gov]

This is the third tyrosinemia patient reported to achieve complete resolution of urinary abnormalities following transplantation, and the only patient in whom renal tubular [ncbi.nlm.nih.gov]

AIDS-Associated Nephropathy

Background There is a high prevalence (30%) of abnormal renal function among patients with HIV disease. [hiv.va.gov]

It does not require dose adjustment in patients with abnormal renal function. [emedicine.com]

Dosage of most NRTIs should be adjusted for impaired renal function (see Table 2 ). [hiv.va.gov]

Focal Embolic Glomerulonephritis

Twelve patients (19%) presented initially to nephrologists with abnormal renal function and/or abnormal urinalysis and were subsequently found to have infective endocarditis [academic.oup.com]

Before delivery, seven of the nine had abnormal renal function. [glowm.com]

CXR and abdominal or renal ultrasound scan (especially if renal function is abnormal): to check for pleural effusion or ascites, the presence of two kidneys, the size and [patient.info]

Familial Interstitial Nephritis

Renal biopsy of the presented case indicated chronic interstitial nephritis without glomerular basement membrane abnormalities. [ncbi.nlm.nih.gov]

Sequential tests in patients with IgG4-related TIN show loss of renal function [4]. [austinpublishinggroup.com]

[…] leading to end-stage renal disease. gouty nephropathy any of a group of chronic kidney diseases associated with the abnormal production and excretion of uric acid. [medical-dictionary.thefreedictionary.com]

Sickle Cell Nephropathy

This abnormality has been characterized functionally as an inability to attain normal maximum osmolality levels in response to water deprivation, despite normal tubular water [annals.org]

Functional tubule abnormalities such as nephrogenic diabetes insipidus result from marked reduction in vasa recta blood flow, combined with ischemic tubule injury. [en.wikipedia.org]

[…] in renal function. [annalsafrmed.org]

Renal Sarcoidosis

Case Report A 43-year-old African-American male with no prior medical history was referred to outpatient nephrology clinic for evaluation of abnormal renal function found [ispub.com]

We report a case of renal-limited sarcoidosis diagnosed by renal biopsy, associated with abnormal calcium metabolism. [ncbi.nlm.nih.gov]

Hypercalcemia is detected in more than 50% of patients, however, it is usually dependent on co-existing renal functional abnormality when the capacity of the kidney to excrete [indianjnephrol.org]

Non-Allergic Interstitial Nephritis

Common (1% to 10%): Abnormal renal function Frequency not reported : Interstitial nephritis, renal failure, allergic/non-allergic glomerulonephritis, nephrotic syndrome, [drugs.com]

In mild cases, the clinical presentation may consist of subtle tubular function abnormalities, such as Fanconi syndrome (ie, aminoaciduria, glycosuria, renal tubular acidosis [emedicine.medscape.com]

The acute reduction in renal function results in both biochemical and clinical abnormalities, related to the inability of the kidney to eliminate water, metabolic by-products [abdominalkey.com]

Scleroderma with Renal Involvement

Case The relationship of hypertension and renal failure in scleroderma to structural and functional abnormalities of the renal cortical circulation Medicine, 53 (1974), pp [reumatologiaclinica.org]

RESULTS: Renal crisis occurred in 129/675 (19.5%) patients. Kidney function abnormalities or proteinuria were present in 173 (26%); 48% had no abnormalities. [jrheum.org]

Acute Tubular Necrosis

BACKGROUND: Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. [ncbi.nlm.nih.gov]

Patients with abnormal renal function prior to the ischaemic or nephrotoxic insult to the kidneys are at a greater risk not only for acute or chronic renal failure but also [academic.oup.com]

The renal functional abnormalities that occur have also been further delineated. [ncbi.nlm.nih.gov]

Post-Infectious Glomerulonephritis

However, the patient reported here had abnormal renal function. Further PCR analyses indicated that he was infected with M. pneumoniae. [ijpmonline.org]

Nearly all patients in both groups regained their baseline renal function without clinical intervention. [scholars.northwestern.edu]

Electrolyte abnormalities Usually not severe, potassium restriction may be required if renal function significantly reduced Volume overload Treat with fluid restriction -400ml [starship.org.nz]

Renal Vascular Disorder

[…] symptoms grade 2 – RAS with controlled hypertension grade 3 – RAS with resistant hypertension, abnormal renal function, or volume overload Epidemiology prevalence 7% in the [medbullets.com]

Functional aspects Effects of abnormal renal function on body fluid Renal disease in its diverse forms can lead to bodily deficits or excesses of water, sodium, potassium, [britannica.com]

While fibromuscular dysplasia can occur anywhere in the body, it often presents in the renal arteries, causing renal hypertension and poor kidney function. [scripps.org]

Renal Function Impairment

[…] are abnormal in up to 30% of HIV-infected patients. 4 AIDS-related kidney disease has become a common cause of end stage renal disease (ESRD) requiring dialysis 4, and kidney [myhivclinic.org]

Background There is a high prevalence (30%) of abnormal renal function among patients with HIV disease. [hiv.va.gov]

Both have low urine concentrations and are not indicated in the treatment of UTI in patients with normal or abnormal renal function. [cjasn.asnjournals.org]

Post-Streptococcal Glomerulonephritis

function. [visualdx.com]

[…] improved and renal function normalized. [ncbi.nlm.nih.gov]

Electrolyte abnormalities Usually not severe, potassium restriction may be required if renal function significantly reduced Volume overload Treat with fluid restriction -400ml [starship.org.nz]

Henoch-Schönlein Purpura

[…] specialist is recommended if there is: Hypertension Abnormal renal function Macroscopic haematuria for 5 days Nephrotic syndrome Acute nephritic syndrome Persistent proteinuria [rch.org.au]

No patients were nephrotic, nephritic or had an abnormal renal function at the initial diagnosis. [doi.org]

[…] proteinuria or macroscopic haematuria at any point should prompt paediatric review with investigations (outlined above) and ongoing follow-up based on results Discussion with a Renal [rch.org.au]

Chronic Kidney Insufficiency

Neither of these studies addressed whether the ARF (or AKI) occurred against a background of normal or abnormal renal function. [cjasn.asnjournals.org]

Impairment of health or a condition of abnormal functioning of the kidney. Impairment of the renal function due to chronic kidney damage. [icd10data.com]

Initially, as renal tissue loses function, there are few noticeable abnormalities because the remaining tissue increases its performance (renal functional adaptation). [merckmanuals.com]

Chronic Pyelonephritis

Nevertheless, in one third of cases the radionuclide studies demonstrated certain abnormalities more readily, including focal parenchymal damage, renal functional impairment [ncbi.nlm.nih.gov]

renal function in the foetus. 8 Generally speaking, sodium and chlorine concentrations higher than 90 mEq/L and osmolalities below 210 mOsm/kg H2O in amniotic fluid suggest [analesdepediatria.org]

The combination of extensive bilateral renal scarring and proteinuria is associated with the worst renal function. [ncbi.nlm.nih.gov]

Tumor Lysis Syndrome

Tumour lysis syndrome is associated with high levels of uric acid, phosphate and potassium along with low levels of calcium and abnormal renal function. [ncbi.nlm.nih.gov]

Function tests, Serum Calcium, Serum Phosphate, serum Uric Acid ) Manage electrolyte abnormalities See Hyperkalemia Management See Hypocalcemia See Hyperuricemia See Hyperphosphatemia [fpnotebook.com]

Function tests, Serum Calcium, Serum Phosphate, serum Uric Acid) Manage electrolyte abnormalities See Hyperkalemia Management See Hypocalcemia See Hyperuricemia See Hyperphosphatemia [fpnotebook.com]

Renal Osteodystrophy

See: - Calcitriol - Hyperparathyroidism - Renal Failure: ( Orders for the CRF Patient ) - Renal Spondyloarthropathy - Vit D - Effects on Adult Bone: - abnormalities of renal [wheelessonline.com]

Renal osteodystrophy (ROD) represents the bone histologic abnormalities resulting from loss of renal function. [clinicaltrials.gov]

The later results mainly from the loss of functioning renal parenchyma and subsequent decreased renal synthesis of active vitamin D. [med.harvard.edu]

Goodpasture Syndrome

Despite minor urinary abnormalities and normal renal function, kidney biopsy may show extensive linear deposits in the glomeruli. [jmedicalcasereports.biomedcentral.com]

Renal function and electrolytes: watch for renal failure. [patient.info]

We present a case of biopsy proven anti-GBM antibody disease with normal renal function, mild urinary abnormalities and positive C-antineutrophil cytoplasmic antibody (C-ANCA [jmedicalcasereports.biomedcentral.com]

Renal Tubular Acidosis

Admission blood tests demonstrated abnormal renal function with a urea of 22 mmol/l (normal: 2.5–7.0 mmol/l) and creatinine of 176 µmol/l (normal: 60–110 µmol/l). [academic.oup.com]

There are four types of renal tubular acidosis, types 1 through 4. The types are distinguished by the particular abnormality in kidney function that causes acidosis. [merckmanuals.com]

Some Types of Renal Tubular Acidosis Type Cause Underlying Abnormality Resulting Symptoms and Metabolic Abnormalities 1 May be hereditary or may be triggered by an autoimmune [merckmanuals.com]

Diabetic Nephropathy

DN is considered the case when there is macroalbuminuria alone or macroalbuminuria together with abnormal renal function. [news-medical.net]

Hyperfiltration, an early functional abnormality, is only a relative predictor for the development of renal failure. [merckmanuals.com]

Diabetic mouse models treated with heparin sulfate and glycosaminoglycan had significant improvement in morphological and functional renal abnormalities[90]. [wjgnet.com]

Shunt Nephritis

In general, early diagnosis and appropriate antibiotic therapy result in marked improvement or disappearance of the concomitant urinary and renal functional abnormalities. [ncbi.nlm.nih.gov]

After removal of the drains as sources of bacteriaemia, renal function improved and the urinary sediment returned to normal. [ntvg.nl]

Early recognition and prompt diagnosis of glomerular disease are essential, because delay in therapy may result in irreversible loss of renal function. [jamanetwork.com]

Urinary Tract Obstruction

The extent of kidney injury in early gestation and the resultant abnormality in kidney development determine fetal outcome and postnatal renal function. [ncbi.nlm.nih.gov]

Obstruction can be due to anatomical or functional abnormalities of the urethra, bladder, ureter, or renal pelvis, which may be congenital or acquired, and it can also occur [oxfordmedicine.com]

It can develop secondary to calculi, tumors, strictures, anatomical abnormalities, or functional abnormalities. [emedicine.medscape.com]

Proximal Renal Tubular Acidosis

Marked deposition of iron in renal proximal tubules was associated with these functional abnormalities. [ncbi.nlm.nih.gov]

Rodriguez-Soriano J: New insights into the pathogenesis of renal tubular acidosis – from functional to molecular studies. Pediatr Nephrol 2000;14:1121–1136. [karger.com]

"New insights into the pathogenesis of renal tubular acidosis--from functional to molecular studies". Pediatr. Nephrol.14:1121–36. 8. [genetics.ouhsc.edu]

Glomerulonephritis

These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. [fpnotebook.com]

[…] in renal function or urinary sediment. [revistanefrologia.com]

Definition (MSH) Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement [fpnotebook.com]

Rapidly Progressive Glomerulonephritis

Despite minor urinary abnormalities and normal renal function, kidney biopsy may show extensive linear deposits in the glomeruli. [jmedicalcasereports.biomedcentral.com]

[…] osteodystrophy 1159 Newark NJ 07112 USA Chapters 17 35 1173 Organ and metabolic complications abnormal endocrine function in chronic renal failure 1236 Neurological aspects [books.google.com]

Follow-up was absolutely normal, and 5 years after transplantation, renal function persisted to be normal, without urinary abnormalities and signs of reactivation of original [ncbi.nlm.nih.gov]

Malignant Hypertension

Abnormal renal function at presentation still predicts worse outcome. [ncbi.nlm.nih.gov]

Patients with MHT are characterized by pronounced target organ damage, including structural and functional cardiac abnormalities. [ncbi.nlm.nih.gov]

The complementary laboratory tests showed normal renal function (serum urea of 19 mg/dL and serum creatinine of 0.7 mg/dL) and normal urinary sediment. [scielo.br]