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69 Possible Causes for Abnormal Renal Function, Hyperreninemia, Hypokalemia

  • Scleroderma with Renal Involvement

    Case The relationship of hypertension and renal failure in scleroderma to structural and functional abnormalities of the renal cortical circulation Medicine, 53 (1974), pp[] Hyperreninemia plays a major role in the pathogenesis of SRC.[] RESULTS: Renal crisis occurred in 129/675 (19.5%) patients. Kidney function abnormalities or proteinuria were present in 173 (26%); 48% had no abnormalities.[]

  • Hypokalemic Nephropathy

    Certain herbal products, like licorice and gan cao may be causative for hypokalemia.[] […] leading to end-stage renal disease. gouty nephropathy any of a group of chronic kidney diseases associated with the abnormal production and excretion of uric acid.[] On the other hand, sustained hypokalemia and hyperreninemia can cause progressive tubulointerstitial nephritis, resulting in end-stage kidney disease (kidney failure).[]

  • Malignant Hypertension

    Hypokalemia and urinary potassium loss were found.[] Abnormal renal function at presentation still predicts worse outcome.[] Initial evaluation demonstrated hyperreninemia with hyperaldosteronism and a possible renal artery stenosis at the contrast-enhanced CT scan.[]

  • Renal Tubular Acidosis

    Subsequently, type 1 RTA due to Sjögren's syndrome was unveiled by sustained hypokalemia (3.3 to 3.4 mEq/L), persistent alkaline urine pH ( 6.0) despite metabolic acidosis[] Admission blood tests demonstrated abnormal renal function with a urea of 22 mmol/l (normal: 2.5–7.0 mmol/l) and creatinine of 176 µmol/l (normal: 60–110 µmol/l).[] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[]

  • Proximal Renal Tubular Acidosis

    Hypokalemia may be associated with it; occasionally leading to features like hypokalemic periodic paralysis.[] Marked deposition of iron in renal proximal tubules was associated with these functional abnormalities.[] Amniocentesis : chloride levels in amniotic fluid Laboratory diagnostics Hypokalemi a and m etabolic alkalosis Hypercalciuria Hyperuricemia ( 50% of cases) Hyperreninemia[]

  • Distal Renal Tubular Acidosis

    The South East Asian cases are associated with more severe hypokalemia.[] "New insights into the pathogenesis of renal tubular acidosis--from functional to molecular studies". Pediatr. Nephrol.14:1121–36. 8.[] Amniocentesis : chloride levels in amniotic fluid Laboratory diagnostics Hypokalemi a and m etabolic alkalosis Hypercalciuria Hyperuricemia ( 50% of cases) Hyperreninemia[]

  • Gitelman Syndrome

    In these children, a tendency towards hypokalemia was first noted during the third week of life.[] Chronic Kidney/Renal Disease Kidney disease means that something is abnormal about the structure or function of one or both kidneys.[] Both probands show hypokalemia, hypochloraemia, hypocalcinuria, hyperreninemia, and hyperaldosteronemia; Proband A has normal serum magnesium and increased urinary sodium[]

  • Bartter's Disease

    Laboratory testing is significant for hypokalemia, hypochloremia, and metabolic alkalosis.[] Patients should avoid strenuous exercise avoided because of the danger of dehydration and functional cardiac abnormalities secondary to potassium imbalance. 56.[] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[]

  • Hypercalcemic Nephropathy

    Also, as the calcium levels were higher, the frequency of hypokalemia was greatest. Why does hypercalcemia cause hypokalemia?[] The calcium causes cumulative functional and histological abnormalities that lead to a decreased glomerular filtration rate and kidney failure. hypercalcemic nephropathy Renal[] […] capacity is due to the presence of calcium in the medulla and the concurrent inflammation which distorts the relationship between the ascending and descending loops Because of hyperreninemia[]

  • Hypoaldosteronism

    A 51-year-old Japanese woman with hypokalemia due to distal renal tubular acidosis associated with Sjögren's syndrome exhibited a decreased plasma aldosterone level despite[] Despite only mildly abnormal renal function, serum K was elevated to 6.2 meq/L, and plasma renin activity (0.12 ng/mL h) and aldosterone (4.4 ng/ dL) failed to respond to[] These results suggest adrenal insensitivity to angiotensin II, possibly a defect in adrenal angiotensin II receptors, as the cause of hypoldosteronism with hyperreninemia[]

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