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153 Possible Causes for Abnormal Serum Protein Electrophoresis

  • Oculocerebrorenal Syndrome

    Lowe syndrome (the oculocerebrorenal syndrome of Lowe, OCRL) is a multisystem disorder characterised by anomalies affecting the eye, the nervous system and the kidney. It is a uncommon, panethnic, X-linked disease, with estimated prevalence in the general population of approximately 1 in 500,000. Bilateral cataract[…][ncbi.nlm.nih.gov]

  • Neuropathy

    Those tests that provide the highest yield of abnormality are blood glucose, serum B12 with metabolites (methylmalonic acid with or without homocysteine) and serum protein[dx.doi.org] […] immunofixation electrophoresis (Level C).[dx.doi.org]

  • Peripheral Neuropathy

    Confirmation may require serum electrophoresis for abnormal serum proteins, electrophysiological studies such as electromyography (EMG), cerebrospinal fluid (CSF) examination[news-medical.net] Those tests that provide the highest yield of abnormality are blood glucose, serum B12 with metabolites (methylmalonic acid with or without homocysteine) and serum protein[dx.doi.org] […] immunofixation electrophoresis (Level C).[dx.doi.org]

  • Orthostatic Hypotension

    […] and urine protein electrophoresis for primary amyloidosis — Diabetic autonomic neuropathy Neuropathic changes associated with poor glycemic control Associated with generalized[aafp.org] ; carpal tunnel syndrome; cardiomyopathy; diarrhea; weight loss Fat aspirate; rectal or gingival biopsy for amyloid deposits; genetic testing for hereditary amyloidosis; serum[aafp.org] Characteristics Diagnosis Treatment Amyloidosis (hereditary and primary) Deposition of amyloid protein in neural tissue Generalized polyneuropathy, prominent pain, and temperature abnormalities[aafp.org]

  • Hypercholesterolemia

    […] dL elevated triglycerides more than 200 mg/dL protein electrophoresis may show abnormal results studies of heart function such as a stress test may be abnormal special studies[lifeextension.com] Laboratory testing may show: total plasma cholesterol greater than 300 mg/dL (adult) total plasma cholesterol greater than 250 mg/dL (child) serum LDL greater than 200 mg[lifeextension.com]

  • Proteus

    […] electrolytes (Na , K , Cl -, HCO 3 -, Ca 2 and PO 4 2-) Provide a screening examination for any abnormalities following renal disease Serum and urine protein electrophoresis[aafp.org] Results are abnormal in multiple myeloma Serum urate In addition to stones, elevated urate can cause tubulointerstitial disease Renal ultrasonography Provides evidence of[aafp.org] […] and syphilis have been associated with glomerular proteinuria Serum albumin and lipid levels Albumin level decreased and cholesterol level increased in nephrotic syndrome Serum[aafp.org]

  • Orthostatic Syncope

    […] and urine protein electrophoresis for primary amyloidosis — Diabetic autonomic neuropathy Neuropathic changes associated with poor glycemic control Associated with generalized[aafp.org] ; carpal tunnel syndrome; cardiomyopathy; diarrhea; weight loss Fat aspirate; rectal or gingival biopsy for amyloid deposits; genetic testing for hereditary amyloidosis; serum[aafp.org] Characteristics Diagnosis Treatment Amyloidosis (hereditary and primary) Deposition of amyloid protein in neural tissue Generalized polyneuropathy, prominent pain, and temperature abnormalities[aafp.org]

  • IgE Myeloma

    An immunoglobulin test is often done when the results of a blood protein electrophoresis or total blood protein test are abnormal.[northshore.org] Serum protein electrophoresis showed an abnormal band in the beta region; serum immunofixation showed free lambda M protein.[oatext.com] Serum Protein Electrophoresis (SPEP) Total Serum Protein References Citations Fischbach FT, Dunning MB III, eds. (2009).[northshore.org]

  • Hypotension

    […] and urine protein electrophoresis for primary amyloidosis — Diabetic autonomic neuropathy Neuropathic changes associated with poor glycemic control Associated with generalized[aafp.org] ; carpal tunnel syndrome; cardiomyopathy; diarrhea; weight loss Fat aspirate; rectal or gingival biopsy for amyloid deposits; genetic testing for hereditary amyloidosis; serum[aafp.org] Characteristics Diagnosis Treatment Amyloidosis (hereditary and primary) Deposition of amyloid protein in neural tissue Generalized polyneuropathy, prominent pain, and temperature abnormalities[aafp.org]

  • Pathological Fracture

    Serum electrophoresis will show an abnormal M peak.[www0.sun.ac.za] The protein is lost into the urine and can be identified by the Bence Jones test or by urine electrophoresis. 2) Metastatic tumour Malignnt tumours that commonly metastasize[www0.sun.ac.za]

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