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164 Possible Causes for Abnormal Smooth Pursuit, Episodes Last about 1.5 Hours, Interictal Downbeat Nystagmus

  • Autosomal Recessive Spinocerebellar Ataxia 8

    smooth pursuit [ Dupré et al 2007 ].[ncbi.nlm.nih.gov] According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[tchain.com] Ocular Motor Functions • Smooth pursuit movements • Saccades • Certain clinical cerebellar syndromes might have characteristic patterns – FRDA1- fixation instability, square[slideshare.net]

    Missing: Episodes Last about 1.5 Hours
  • Familial Episodic Pain Syndrome Type 1

    smooth pursuit EA5 613855 AD CACNB4 (2q22-23) P/Q type calcium channel 20 Hours Vertigo, dysarthria Nystagmus, ataxia β4 subunit EA6 612656 AD or sporadic SLC1A3 (5p13.2)[e-jmd.org] Most patients also show various interictal nystagmus, such as gaze-evoked nystagmus (GEN), rebound nystagmus, or primary position downbeat nystagmus.[e-jmd.org] Unknown 1-42 1 min to 6 h Vertigo, diplopia, weakness, tinnitus, headache, visual blurring Myokymia EA4 606552 AD Unknown Unknown 23-60 Brief Vertigo, diplopia Nystagmus, abnormal[e-jmd.org]

  • Spinocerebellar Ataxia Type 26

    Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major[…][books.google.com]

    Missing: Episodes Last about 1.5 Hours Interictal Downbeat Nystagmus
  • Autosomal Recessive Spastic Paraplegia Type 18

    WHO-ICD-10 version:2010 Diseases of the nervous system Systemic atrophies primarily affecting the central nervous system Mode of Inheritance Autosomal recessive Gene Map Locus Hereditary spastic paraplegia (HSP) is a group of clinically and genetically diverse disorders that share a primary feature, which is the[…][cags.org.ae]

    Missing: Episodes Last about 1.5 Hours Interictal Downbeat Nystagmus
  • Alpha-Mannosidosis

    Alpha-mannosidosis is a lysosomal storage disorder, first described by Swedish physician Okerman in 1967. In humans it is known to be caused by an autosomal recessive genetic mutation in the gene MAN2B1, located on chromosome 19, affecting the production of the enzyme alpha-D-mannosidase, resulting in its deficiency.[…][en.wikipedia.org]

    Missing: Episodes Last about 1.5 Hours Interictal Downbeat Nystagmus
  • Spinocerebellar Ataxia Type 6

    Eye movement abnormalities such as gaze evoked and downbeat nystagmus, impaired smooth pursuit and abnormal vestibulo-ocular reflex are commonly seen in SCA6 patients.[orpha.net] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] However, eye movement abnormalities (saccadic intrusions in smooth pursuit and gaze evoked nystagmus) were detected in these 2 patients.[doi.org]

    Missing: Episodes Last about 1.5 Hours
  • Episodic Ataxia

    smooth pursuit EA5 613855 AD CACNB4 (2q22-23) P/Q type calcium channel 20 Hours Vertigo, dysarthria Nystagmus, ataxia β4 subunit EA6 612656 AD or sporadic SLC1A3 (5p13.2)[e-jmd.org] According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[dizziness-and-balance.com] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com]

    Missing: Episodes Last about 1.5 Hours
  • Spastic Ataxia with Congenital Miosis

    […] nystagmus, and impaired smooth pursuit.[findzebra.com] Symptoms INHERITANCE: Autosomal recessive HEAD AND NECK: [Eyes]; Impaired smooth pursuit; Abnormal saccades; Nystagmus; Optic atrophy (67%) ABDOMEN: [Gastrointestinal]; Dysphagia[findzebra.com] […] optokinetic response 379.58 Deficiencies of smooth pursuit movements 379.59 Other irregularities of eye movements Opsoclonus 379.6 Inflammation (infection) of postprocedural[theodora.com]

    Missing: Episodes Last about 1.5 Hours
  • Alcoholic Cerebellar Degeneration

    pursuits, intention tremor, or speech abnormalities.[mdedge.com] . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] […] cerebellar disorder include: impaired heel-shin test, impaired finger-nose-finger test (dysmetria), impaired rapid alternating movements (dysdiadochokinesia), nystagmus, impaired smooth[mdedge.com]

    Missing: Episodes Last about 1.5 Hours
  • Spinocerebellar Ataxia Type 4

    […] being responsible for smooth eye pursuit movement, the modulation and amplitude of saccades, and visual suppression of caloric induced nystagmus [ 18 ].[tinnitusjournal.com] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] Oculomotor abnormalities in patients with cerebellar dysfunction exist and it is known that the cerebellum influences the maintenance of the eccentric portion of the eye,[tinnitusjournal.com]

    Missing: Episodes Last about 1.5 Hours