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65 Possible Causes for Abnormal Spikes, Paroxysmal Activity - Generalized Spikes

  • Epilepsy

    […] waves, multifocal discharges, generalized paroxysmal fast activity, diffuse slowing slow background, generalized spike waves MRI normal normal vermis hypoplasia, cisterna[ncbi.nlm.nih.gov] (spikes and slow waves); (d) occurrence at any age in childhood and adulthood; (e) frequently demonstrable aetiology (tumor, vascular); and (f) no progressive evolution of[medlink.com] If you have epilepsy, the EEG may show abnormal spikes or waves in your brain's electrical activity patterns. Different types of epilepsy cause different patterns.[northshore.org]

  • Idiopathic Generalized Epilepsy

    Generalized spike-wave discharges and diffuse paroxysmal fast activity were categorized as interictal and ictal, based on duration of less than 10 seconds or greater, respectively[ncbi.nlm.nih.gov] The abnormalities included generalized spike-wave and/or spike-polyspike morphology in majority.[annalsofian.org] Abstract Magnetic resonance imaging (MRI) techniques have been used to quantitatively assess focal and network abnormalities.[ncbi.nlm.nih.gov]

  • Myoclonic-Astatic Epilepsy

    generalized paroxysmal fast activity or focal spikes.[jamanetwork.com] The type of abnormal activity is called ‘spike and wave’ or ‘polyspike and wave’. Children with myoclonic-astatic epilepsy are not usually photosensitive.[epilepsy.org.uk] EEG abnormality is enhanced by sleep deprivation and by sleep. Generalized spike-and-wave often becomes fragmented with sleep deprivation or in sleep.[medlink.com]

  • Juvenile Myoclonic Epilepsy

    We compared the occurrence and involvement of posterior electrodes for focal abnormalities and generalised spike-wave activity in the EEG outside photic stimulation between[ncbi.nlm.nih.gov] […] discharges on electroencephalography, and a lack of focal abnormality on magnetic resonance imaging (MRI).[ncbi.nlm.nih.gov] Neuroimaging typically reveals no abnormalities and EEG frequently reveals generalized spike-wave activity at a frequency of 4-6 hertz.[meddean.luc.edu]

  • Benign Adult Familial Myoclonic Epilepsy

    Landau-Kleffner Syndrome and Continuous Spike wave in slow wave sleep: The epileptiform abnormalities seen during sleep EEG in these children is markedly increased compared[epilepsyfoundationmn.org] EEG shows generalized spike waves and polyspike waves, early photosensitivity, and focal abnormalities.[euroformhealthcare.biz] EEG findings include a photomyoclonic response along with abnormality of polyspikes and waves.[medlink.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    Jerk-locked premyoclonus spikes Hand tremor Neuronal loss in central nervous system Cutaneous photosensitivity Hyperreflexia Heterogeneous Weight loss Dystonia Splenomegaly[mendelian.co] Abnormal asymmetry in benign epilepsy with unilateral and bilateral centrotemporal spikes: a combined fMRI and DTI study.[frontiersin.org] EEG abnormalities are more likely or increased with sleep deprivation and during sleep.[epilepsy.com]

  • West Syndrome

    Brain MRI revealed no abnormal findings although interictal EEG demonstrated left centro-parieto-temporal localized spike foci.[ncbi.nlm.nih.gov] The patient was followed up to 13 years of age, and at the last examination was shown to have severe speech delay, seizures, and continuous spike-and-wave activity on EEG.[ncbi.nlm.nih.gov] Abnormality may only be seen in sleep or on wakening.[epilepsydiagnosis.org]

  • Juvenile Absence Epilepsy

    Multiunitary activity analysis of cortical and subcortical structures in paroxysmal discharges and grand mal seizures in photosensitive baboons.[academic.oup.com] Although focal spikes can occur, if they consistently arise in 1 area, consider structural brain abnormality. Caution . If slow spike-and-wave ( Imaging.[medlink.com] The electroencephalogram (EEG) can show focal and generalised abnormalities (sharp waves, spikes or spike and slow waves).[epilepsy.org.uk]

  • Encephalopathy

    *Seen in Anoxic brain damage, CNS supressant drugs and severe hypothermia *Paradoxical arousal response *A stimulus brings out slower activity with generalized high voltage[slideshare.net] Structural abnormalities can often be seen on cranial MRI.[orpha.net] […] delta bursts, that is called as paradoxical arousal response 18. * Background slowing * Increased theta delta activity * Paroxysmal sharp waves * Theta bursts * Delta bursts[slideshare.net]

  • Uremic Encephalopathy

    Preterminally, the patient becomes immobile and mute. 43 Investigation of dialysis dementia Abnormalities in EEG may precede clinically overt symptoms by up to 6 months.[jnnp.bmj.com] Intermittent bursts of high voltage slowing and spike and wave activity are noted, particularly in the frontal leads. 44 The EEG may show an initial deterioration after treatment[jnnp.bmj.com]

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