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1,620 Possible Causes for Abnormal Spine X-Ray, Alkaline Phosphatase Increased, Severely Disproportionate Short Stature

  • Osteogenesis Imperfecta

    […] bone disease by taking X-rays.[healthline.com] Blood calcium, phosphate, albumin, fasting urinary calcium/creatinine ratio, total serum alkaline phosphatase, and bone alkaline phosphatase were obtained at baseline and[ncbi.nlm.nih.gov] Pseudoachondroplasia usually manifests in the 2 nd year of life with ligamentous laxity and tends to develop severe disproportionate short stature.[doi.org]

  • Systemic Mastocytosis

    In multivariate analysis of all patients, an increased spleen volume 450 ml (hazard ratio (HR), 5.2; 95% confidence interval (CI), (2.1-13.0); P 0.003) and an elevated alkaline[ncbi.nlm.nih.gov] Preoperative laboratory investigations were normal, except for moderate anemia (hemoglobin 99 g/L), increased alkaline phosphatase (196 U/L, normal 36-108 U/L), and decreased[journals.lww.com] phosphatase levels 218 U/I (normally 198 U/I); increased gamma glutamyl transpeptidase levels (223 IU/mL); hemostatic mechanism within reference values (APTT 0.88: PT 1.91[cyberleninka.org]

    Missing: Severely Disproportionate Short Stature
  • Pseudoachondroplasia

    Lateral flexion-extension x-rays of the cervical spine is recommended, if a pre-existing abnormality such as os odontoideum or hypoplastic odontoid is present.[web.archive.org] Clinical evaluation revealed that PSACH patients in this pedigree had a severe disproportionate short stature (-10SD).[ncbi.nlm.nih.gov] Definition A skeletal dysplasia usually manifesting in the second year of life and characterized by moderate to severe disproportionate short stature, deformity of the lower[uniprot.org]

    Missing: Alkaline Phosphatase Increased
  • Osteoporosis

    Increased rates of osteoclastic bone resorption, measured by the level of collagen breakdown products, as well as increased bone formation, measured by bone-specific alkaline[doi.org] phosphatase, osteocalcin, or procollagen peptide levels, are associated with an increase in risk for bone loss and fragility fractures.[doi.org]

    Missing: Severely Disproportionate Short Stature
  • Osteoarthritis

    High leptin levels in osteoarthritis might play a role in increased levels of bone markers, such as alkaline phosphatase and osteocalcin observed in osteoblasts (Dumond et[ncbi.nlm.nih.gov] Moreover, several clinical ex/in vivo and in vitro studies have confirmed the presence of elevated alkaline phosphatase activity and increased osteocalcin levels in primary[ncbi.nlm.nih.gov]

    Missing: Severely Disproportionate Short Stature
  • Hypophosphatasia

    BACKGROUND: Hypophosphatasia is a rare autosomal recessive metabolic disorder characterized by low serum and tissue alkaline phosphatase activity, increased urinary excretion[ncbi.nlm.nih.gov] We investigated a mother and daughter with features of CCD presenting with reduced plasma alkaline phosphatase activity, increased urinary phosphoethanolamine excretion and[ncbi.nlm.nih.gov] Serum alkaline phosphatase (ALP) levels increased as high as 12,700 U/L during treatment. Any side effect related to AA was not observed.[ncbi.nlm.nih.gov]

    Missing: Severely Disproportionate Short Stature
  • Growth Failure

    Lateral skull : midface hypoplasia, frontal prominence Spine : abnormally narrow interpedicular distance spinal canal stenosis ; scoliosis Extremities: bones are short and[amboss.com] Healing occurs in 2–4 weeks and can be monitored from the lowering of alkaline phosphatase, increasing vitamin D levels and healing on X-rays, but complete reversal of bony[slideplayer.com] A distinctive autosomal recessive syndrome of severe disproportionate short stature with short long bones, brachydactyly, and hypotrichosis in two consanguineous arab families[advbiores.net]

  • Spinal Metastasis

    […] of the spine to be followed by an MRI with gadolinium if any abnormality is found.[brainmetsbc.org] Alkaline phosphatase: When the bones dissolve, the levels of alkaline phosphatase or ALP may increase.[cancer.org] , like numbness, tingling, and intermittent "electrical" sensations Diagnosis Back pain with an unknown cause and without any other symptoms may be first evaluated by an x-ray[brainmetsbc.org]

    Missing: Severely Disproportionate Short Stature
  • Multiple Myeloma

    Similarly, in one other small study (n 46) in which PET/CT, MRI, and X-rays were compared, MRI of spine–pelvis detected diagnostic abnormalities in 92% of patients, whereas[ncbi.nlm.nih.gov] Hepatic manifestations, observed in 30% of patients, usually consist of liver enlargement, accompanied by isolated increased serum alkaline phosphatase levels, without evidence[ojrd.biomedcentral.com] Organ involvement may include progressive heart failure, nephrotic syndrome and/or renal failure, hepatomegaly and/or an increased level of serum alkaline phosphatase, autonomic[karger.com]

    Missing: Severely Disproportionate Short Stature
  • Osteomyelitis

    Dynamic, or flexion/extension X-rays (X-rays that show the spine in motion) may be obtained to see if there is any abnormal or excessive movement or instability in the spine[columbiaspine.org] […] bone disease by taking X-rays.[healthline.com] Spinal dislocation or slippage (also known as spondylolisthesis), kyphosis, scoliosis, as well as local and overall spine balance can be assessed with X-rays.[columbiaspine.org]

    Missing: Severely Disproportionate Short Stature

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