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26 Possible Causes for Abnormal Visual Evoked Responses, Astrocytic Gliosis

  • Globoid Cell Leukodystrophy

    […] brainstem evoked responses; and 50% (n 6) exhibited abnormal visual evoked responses.[ncbi.nlm.nih.gov] ] a metabolic disorder of infancy or early childhood characterized by spasticity, seizures, and rapidly progressive cerebral degeneration, massive loss of myelin, severe astrocytic[medical-dictionary.thefreedictionary.com] The presence of numerous, often multinucleated, globoid cells, the almost total loss of myelin and oligodendroglia, and astrocytic gliosis in the white matter are the morphologic[mhmedical.com]

  • Demyelinating Disease

    As lesions evolve, there is prominent astrocytic proliferation (gliosis).[accessmedicine.mhmedical.com] Astrocytic gliosis in plaques is usually evident in sections stained with haematoxylin and eosin, but can be observed more obviously by immunolabelling the astrocytes—for[ncbi.nlm.nih.gov] Edema Differentiate inactive plaques in MS Little to no myelin Decreased oligodendrocyte nuclei Gliosis *Decreased number of axons (degeneration) Differentiate shadow plaques[quizlet.com]

  • Primary Progressive Multiple Sclerosis

    […] remission of symptoms, and demonstrable delayed blink reflex and evoked visual response are diagnosed as having either possible or probable multiple sclerosis.[medical-dictionary.thefreedictionary.com] As lesions evolve, there is prominent astrocytic proliferation (gliosis) [ 11 ].[omicsonline.org] There is no definitive diagnostic test for the condition, but persons with objectively measured abnormalities of the central nervous system, a history of exacerbation and[medical-dictionary.thefreedictionary.com]

  • Multiple Sclerosis

    Multiple sclerosis (MS) is characterised by inflammation, demyelination, axonal or neuronal loss, and astrocytic gliosis in the central nervous system (CNS), which can result[ncbi.nlm.nih.gov] Proliferation of astrocytes (glial cells) in damaged areas of the central nervous system HLA‐DR Major histocompatability complex (MHC) class II cell surface receptor encoded[doi.org] […] of the myelin sheath insulating the nerves Dysarthria Having a problem with articulating Erythrocyte extravasation Leakage of red blood cells into the surrounding tissue Gliosis[doi.org]

  • Neuromyelitis Optica

    In active multiple sclerosis (MS) lesions astrocytes reveal changes of reactive protoplasmatic or fibrillary gliosis.[doi.org] gliosis ( c ); the astrocytes express GFAP and AQP1 and 4; (patient 499, spinal cord) 30. d – g Lesion type 4 shows selective loss of AQP4 ( e ), while myelin sheaths ( d[doi.org] They showed an extensive loss of myelin, oligodendrocytes and axons and a profound fibrillary gliosis with densely packed GFAP and AQP1 reactive astrocytic processes, while[doi.org]

  • Pelizaeus-Merzbacher Disease

    No fibrous gliosis is present but there are Alzheimer type 2 astrocytes in the cortex. CD is caused by mutations of ASPA , which encodes the enzyme Aspartoacylase.[neuropathology-web.org]

  • Diffuse Cerebral Sclerosis of Schilder

    […] and scattered astrocytes with absence of oligodendroglia, axons, myelin, and inflammatory cells (, 2 ).[doi.org] […] middle layer zone (Schaumburg zone 2), showing perivascular inflammatory cells and demyelination with preservation of axons; and a central zone (Schaumburg zone 3), showing gliosis[doi.org]

  • Subacute Sclerosing Panencephalitis

    There is often evidence of neuronal degeneration, gliosis, proliferation of astrocytes, perivascular cuffing, lymphocytic and plasma cell infiltration, and demyelination.[doi.org]

  • Alpers Syndrome

    EEG showed marked and distinctive slow wave abnormality, visual evoked responses were diminished, and cerebral atrophy was seen on CT scan.[ncbi.nlm.nih.gov] The neuropathology of vCJD is characteristic with grey matter spongiform degeneration, reactive astrocytic gliosis, and “florid plaques” which are pathognomonic of vCJD.[jnnp.bmj.com] Visual evoked response was abnormal in 5 of 10 cases.[nature.com]

  • Leigh's Disease

    Flash visual evoked responses, brain-stem auditory evoked responses, and the interictal electroencephalogram did not contributed to diagnosis.[ncbi.nlm.nih.gov] In addition, there was severe leukoencephalopathy of the cerebral hemispheres with sudanophilic tissue degregation, advanced axonal loss and reactive astrocytic gliosis.[ncbi.nlm.nih.gov] Longstanding chronic lesions involved the optic chiasma and the cerebral peduncles and consisted of myelin loss, status spongiosus, astrocytic gliosis and marked capillary[ncbi.nlm.nih.gov]

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