Absence of Necrosis: Causes & Reasons

Possible Causes for Absence of Necrosis

We report on 2 sibs with desquamative interstitial pneumonia. The female died at age 1 7/12 years despite use of prednisolone and methylprednisolone, while the male, now age 3 years. is alive with oxygen support. The occurrence of desquamative interstitial pneumonia in sibs born to normal parents suggests that in[…] [ncbi.nlm.nih.gov]

Congenital Pericardium Anomaly

The absence of focal necrosis on delayed-enhancement CMR, which can detect minuscule focal necrosis in the absence of a functional defect, indicates that causes related to [ncbi.nlm.nih.gov]

We report a case of congenital absence of the pericardium that was discovered in the throes of acute myocardial necrosis. [ncbi.nlm.nih.gov]

The case of a 49-year-old woman is described who presented with acute myocardial necrosis and absence of obstructive coronary artery disease, and in whom a complete left pericardial [ncbi.nlm.nih.gov]

Distal Myopathy Type 4

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Disseminated Peritoneal Leiomyomatosis

Leiomyosarcoma is discarded in the absence of necrosis and morphological features of malignancy, a low proliferation index and clinical context (absence of pulmonary localizations [scirp.org]

This examination confirms a proliferation of smooth muscle fibers without mitosis or atypia or necrosis. [scirp.org]

Anal Neuroendocrine Tumor

CD56 immunostaining is more specific than synaptophysin for its diagnosis CDX2 expression may indicate the site of origin of this type of tumor Presence / absence of necrosis [pathologyoutlines.com]

Bizarre Leiomyoma

[…] of cytologic atypia and tumor cell necrosis (Table 3) Epithelioid STUMP: Mitoses: ≥ 2/10 high power fields) and < 4/10 high power fields in the absence of cytologic atypia [pathologyoutlines.com]

[…] and tumor cell necrosis (Table 4) Leiomyosarcoma: Uterine spindle cell leiomyosarcoma (Table 2): 2 or more morphologic criteria of malignancy: Cytologic atypia Tumor cell [pathologyoutlines.com]

J Surg Pathol 2016;40:923, Cancer 2014;120:3165, Am J Surg Pathol 1997;21:1261) Alveolar edema, staghorn vessels Low mitotic activity (< 5 mitoses/10 high power fields) Absence [pathologyoutlines.com]

Childhood Thymoma

[…] along with absence of myasthenia gravis. [ncbi.nlm.nih.gov]

Extensive necrosis is seldom seen in thymoma with only a few reports mentioning necrosis in adult patients. [ncbi.nlm.nih.gov]

[…] this article, we report a case of a thymoma in an 8-year-old boy, who had favorable histopathology (Masaoka stage I, WHO type B2), despite the presence of young age and necrosis [ncbi.nlm.nih.gov]

Intravascular Papillary Endothelial Hyperplasia

The presence of papillary structures lined by a single row of endothelial cells (Figure 4), absence of pleomorphism, mitosis, and necrosis in vascular lumen was confirmed [diagnosticpathology.biomedcentral.com]

[…] of atypia, necrosis, pleomorphism.14,15 However, adjuvant radiotherapy may be required in intracranial Masson’s tumor to prevent recurrence or to treat patients whose lesion [dovepress.com]

[…] and solid areas; and iv) absence of mitotic figures and cellular pleomorphism (7). [spandidos-publications.com]

Retroperitoneal Leiomyosarcoma

Calcifications and necrosis are uncommon in the absence of treatment. [pubs.rsna.org]

The presence of calcifications and absence of necrosis in a paravertebral mass suggest ganglioneuroma over leiomyosarcoma (4). Paraganglioma. [pubs.rsna.org]

and lack of necrosis. [pubs.rsna.org]

Juxtacortical Chondroma

There is absence of necrosis. [ncbi.nlm.nih.gov]

Comedo Carcinoma

[…] of necrosis (Lancet 1995;345:1154, Hum Pathol 1998;29:1056, Cancer 1997;80:1798, Surg Clin North Am 1990;70:853) Nuclear grade: Low grade: Monotonous, round nuclei with smooth [pathologyoutlines.com]

[…] of intraductal comedo-type necrosis. [breast-cancer.ca]

No universally accepted grading system for DCIS but more recently endorsed classification systems stratify DCIS by nuclear grade (low, intermediate, high) and presence or absence [pathologyoutlines.com]

Acute Tubular Necrosis

Acute tubular necrosis is rarely associated with macroscopic hematuria in the absence of other genitourinary abnormalities. [ncbi.nlm.nih.gov]

[…] in the absence of graft rejection. [ncbi.nlm.nih.gov]

Absence of renal perfusion does not indicate a nonviable kidney. [ncbi.nlm.nih.gov]

Granulomatous Prostatitis

Various scientific literatures reveal, that the histological absence of caseation necrosis and granulomas, does not rule out the diagnosis of tuberculosis. [ncbi.nlm.nih.gov]

Sarcoid Myocarditis

Absence of widespread necrosis. [histopathology-india.net]

There is absence of coagulative necrosis and coronary artery disease. [ispub.com]

[…] chronic inflammatory changes (including giant cells) Chronic persistent myocarditis - Less distinct onset of illness; persistent histologic infiltrate with foci of myocyte necrosis [emedicine.medscape.com]

Gemistocytic Astrocytoma

The absence of mitoses, necrosis, and vascular endothelial proliferation are important negative features. [jlponline.org]

[…] of necrosis and endothelial proliferation. [thamburaj.com]

[…] of necrosis, as "multilayered, mitotically active endothelial cells together with smooth muscle cells/pericytes." [1] However, patients whose glioblastoma diagnosis depended [emedicine.medscape.com]

Cecal Volvulus

The concept that this lesion requires resection in the absence of necrosis cannot be supported by our data. [ncbi.nlm.nih.gov]

The concept that this lesion requires resection in the absence of necrosis cannot be supported by our data. ( Arch Surg 115:273-277, 1980) [jamanetwork.com]

In patients considered at high surgical risk (very old, severe comorbidity) a conservative solution is reasonable in absence of cecal necrosis. [ispub.com]

Stomach Perforation

The total absence of coagulation necrosis of the stomach or other portions of the gastrointestinal tract and the absence of burns of the abdominal wall were other unique features [ncbi.nlm.nih.gov]

Eosinophilic Angiocentric Fibrosis

Characteristically there is an absence of fibrinoid necrosis or true granuloma and the mucosa is typically respected. [elsevier.es]

Absence of geographic necrosis, necrotizing vasculitis, and granulomatous inflammation excludes Wegener’s granulomatosis (WG) and Churg-Strauss syndrome (CS). [dev.docslide.net]

Absence of dense lymphoid aggregates with prominent germinal centers excludes Kimura’s disease. [dev.docslide.net]

Anaerobic Bacterial Infection

Anaerobic — Living and growing in the absence of oxygen. Necrosis — Tissue death and destruction resulting from infection or disease. [encyclopedia.com]

Proliferating Trichilemmal Cyst

[…] of pathologic mitoses, necrosis and invasion of nerves or vessels Behaves in a benign manner Group 2: Similar to group 1 but manifest irregular, locally invasive silhouettes [pathologyoutlines.com]

Group 1 PPTs are circumscribed with "pushing" margins and have modest nuclear atypia with absence of mitoses, necrosis, and angioinvasion; group 2 PPTs are similar to group [jdrntruhs.org]

[…] of lymphovascular invasion and necrosis and absence of a local or distant organ metastasis and recurrence despite a 12-month follow-up, which clinically supports this conclusion [symbiosisonlinepublishing.com]

Vulvar Leiomyosarcoma

Any coagulative tumor cell necrosis In the absence of tumor cell necrosis, the diagnosis requires diffuse, moderate to severe cytological atypia and a mitotic index of >5mf [sarcomahelp.org]

*mf/hpf = mitotic figures/high power fields Any coagulative tumor cell necrosis In the absence of tumor cell necrosis, the diagnosis requires diffuse, moderate to severe cytological [sarcomahelp.org]

In the absence of coagulative tumor cell necrosis and significant atypia, a high mitotic index is compatible with a benign clinical course. [sarcomahelp.org]

Giant Cell Myocarditis

Absence of widespread necrosis. [histopathology-india.net]

In idiopathic lymphocytic myocarditis there is a paucity of giant cells and absence of large foci of necrosis. [path.upmc.edu]

Admixed with the infiltrate were fibroblastic proliferation and multinucleated giant cells in the absence of sarcoid like granuloma. [ncbi.nlm.nih.gov]

Primary Cardiac Sarcoma

Foci of tumor necrosis were also seen [Figure - 2]. [ijpmonline.org]

Factors associated with increased survival after a resection of cardiac sarcoma are a left-sided location, mitotic rate less than 10 per high power field and absence of necrosis [cardiothoracicsurgery.biomedcentral.com]

The involvement of the right atrium, absence of tumor necrosis, presence of pericardial effusion, and valve preservation have been described as signs suggestive of cardiac [scmr.org]

Granulomas

Important morphological features include the presence or absence of necrosis, the nature of the infiltrate and surrounding biopsy specimen, and the presence of organisms or [aasldpubs.onlinelibrary.wiley.com]

[…] of necrosis is an important finding that helps to categorize epithelioid cell granulomas. [ijdpdd.com]

Click here to view Figure 3: Sarcoidal granuloma composed predominantly of epithelioid cells with paucity of lymphocytes (H and E, ×400) Click here to view The presence or absence [ijdpdd.com]

Cerebellar Liponeurocytoma

Its salient morphological characteristics are advanced neuronal/neurocytic differentiation, the presence of lipomatous areas, low mitotic rate, and the absence of necrosis [ncbi.nlm.nih.gov]

The absence of mitotic activity, necrosis and endothelial proliferation suggest the low proliferative nature of these tumors and favorable prognosis ( Akhaddar et al., 2003 [em-consulte.com]

The absence of mitoses, necrosis, vascular hyperplasia, and nucleo-cytoplasmic atypia, and the low proliferation rate (MIB-1 < 6%) favor the interpretation of a benign lesion [jmedicalcasereports.biomedcentral.com]

Hemoconcentration

The absence of admission hemoconcentration had strong NPV for necrosis. [insights.ovid.com]

Neither the presence nor the absence of hemoconcentration at admission was associated to severity, necrosis or OF (Table 1). [wjgnet.com]

The absence of hemoconcentration at admission or a drop in 24-hour hematocrit level was reliable in predicting that patients would not develop necrosis (NPV of 94.7% for hematocrit [insights.ovid.com]

Chronic Lymphadenitis except Mesenteric

If foamy histiocytes predominated in the KFD lesions, the case was classified as xanthomatous regardless of the presence or absence of necrosis. [slideshare.net]

The diagnosis of Kikuchi Disease is made histologically and is characterized by paracortical areas of necrosis and a notable complete absence of neutrophils. [ncbi.nlm.nih.gov]

[…] and immunoblasts surrounding the area of necrosis, and the absence of granulocytes ( 5, 6 ). [ajnr.org]

Frontal Sinus Schneiderian Papilloma

Respiratory epithelial adenomatoid hamartoma: Downward proliferation of respiratory mucosa can mimic inverted papilloma Surrounded by a thickened basement membrane Absence [pathologyoutlines.com]

Nonkeratinizing squamous cell carcinoma: Infiltrative growth, irregular border, marked nuclear atypia, frequent mitoses, desmoplastic reaction, unequivocal invasion and tumor necrosis [pathologyoutlines.com]

Pulmonary Gangrene

Anaerobic — Living and growing in the absence of oxygen. Necrosis — Tissue death and destruction resulting from infection or disease. [encyclopedia.com]

[…] of large sections of lung tissue, the absence of pronounced granulation of the shaft. [eurodoctor.ucoz.com]

Severity of lung necrosis was measured on the basis of the absence of contrast uptake in computed tomography. [journals.plos.org]

Anaplastic Oligodendroglioma

The absence of necrosis and the presence of endothelial abnormalities were correlated with better outcomes. [ncbi.nlm.nih.gov]

CONCLUSIONS: Small cell astrocytoma is an aggressive histologic variant that behaved like primary GBM, even in the absence of endothelial hyperplasia and necrosis. [ncbi.nlm.nih.gov]

absence of endothelial abnormalities and/or necrosis, 1p/19q codeletion and Isocitrate dehydrogenase 1 (IDH1) mutation were independent factors that predicted better PFS [ncbi.nlm.nih.gov]