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10 Possible Causes for Absence of Stratum Granulosum

  • Congenital Reticular Ichthyosiform Erythroderma

    We present an unusual new clinical feature which developed in a patient with congenital reticular ichthyosiform erythroderma. This rare ichthyotic disorder is characterized by erythematous ichthyotic skin surrounding slowly enlarging areas of normal skin, and by a pathognomonic ultrastructural pattern, namely[…][ncbi.nlm.nih.gov]

  • Netherton Syndrome

    We developed a monoclonal antibody giving a strong signal for LEKTI in the stratum granulosum of normal skin and demonstrated absence of the protein in NTS epidermis.[ncbi.nlm.nih.gov]

  • Refsum Disease

    Stratum granulosum-stratum corneum junctions also showed co-existence of non-lamellar and lamellar domains, indicative of lipid phase separation.[ncbi.nlm.nih.gov] Also, partial detachment or complete absence of corneocyte lipid envelopes (CLE) was seen in the stratum corneum of all RD patients.[ncbi.nlm.nih.gov]

  • Peeling Skin Syndrome

    If a patient previously diagnosed with EB shows continuous superficial peeling, histological properties of cleavage between stratum corneum and stratum granulosum, and/or[dermatologyadvisor.com] […] of the stratum corneum or a few layers of parakeratosis, which tend to be separated from the stratum granulosum.[pcds.org.uk] absence of associated desmin genes, screening for mutations of PSS may be warranted.[dermatologyadvisor.com]

  • Acral Peeling Skin Syndrome

    If a patient previously diagnosed with EB shows continuous superficial peeling, histological properties of cleavage between stratum corneum and stratum granulosum, and/or[dermatologyadvisor.com] […] of the stratum corneum or a few layers of parakeratosis, which tend to be separated from the stratum granulosum.[pcds.org.uk] absence of associated desmin genes, screening for mutations of PSS may be warranted.[dermatologyadvisor.com]

  • Exfoliative Ichthyosis

    If a patient previously diagnosed with EB shows continuous superficial peeling, histological properties of cleavage between stratum corneum and stratum granulosum, and/or[dermatologyadvisor.com] absence of associated desmin genes, screening for mutations of PSS may be warranted.[dermatologyadvisor.com]

  • Generalized Peeling Skin Syndrome

    If a patient previously diagnosed with EB shows continuous superficial peeling, histological properties of cleavage between stratum corneum and stratum granulosum, and/or[dermatologyadvisor.com] […] of the stratum corneum or a few layers of parakeratosis, which tend to be separated from the stratum granulosum.[pcds.org.uk] absence of associated desmin genes, screening for mutations of PSS may be warranted.[dermatologyadvisor.com]

  • Peeling Skin Syndrome Type A

    If a patient previously diagnosed with EB shows continuous superficial peeling, histological properties of cleavage between stratum corneum and stratum granulosum, and/or[dermatologyadvisor.com] […] of the stratum corneum or a few layers of parakeratosis, which tend to be separated from the stratum granulosum.[pcds.org.uk] absence of associated desmin genes, screening for mutations of PSS may be warranted.[dermatologyadvisor.com]

  • Skin Peeling or Scaling

    […] of the stratum corneum or a few layers of parakeratosis, which tend to be separated from the stratum granulosum.[pcds.org.uk] […] layer Type B (inflammatory) PSS This is characterised by erythematous migratory patches with a peeling border, pruritus, and a tendency towards atopy Histology can show an absence[pcds.org.uk]

  • Zosteriform Lentiginosis

    Electron microscopic studies have shown increased numbers of transitional cells between the stratum granulosum and stratum corneum.[what-when-how.com] Histologically , studies show hyperkeratosis, decreased granular cell layers, papillomatosis, absence of sweat glands, and fragmentation of elastic fibers.[what-when-how.com]

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