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91 Possible Causes for Absent Ankle Reflex, Severe Peripheral Motor Neuropathy

  • Peripheral Neuropathy

    Most people with PN have reduced or absent ankle reflexes (involuntary responses to a stimulus).[thebody.com] We treated a 52-year-old man who had severe disabling classic peripheral neuropathy since 1998 with Scrambler Therapy (Calmare), an FDA-cleared peripheral non-invasive neuromodulation[ncbi.nlm.nih.gov] Classically, ankle jerk reflex is absent in peripheral neuropathy.[en.wikipedia.org]

  • Diabetic Autonomic Neuropathy

    Diabetic autonomic neuropathy is a subgroup of diabetic neuropathy, a group of nerve diseases affecting the peripheral nerves outside the brain and spinal cord.[columbianeurology.org] Signs and symptoms [ edit ] Illustration depicting areas affected by diabetic neuropathy Diabetic neuropathy affects all peripheral nerves including sensory neurons, motor[en.wikipedia.org] There are three kinds of peripheral nerves: motor, sensory, and autonomic. Motor nerves carry signals to different muscle groups.[columbianeurology.org]

  • Diabetic Polyneuropathy

    The ankle tendon reflex was absent in almost half of our patients (40.4 %).[em-consulte.com] Signs and symptoms [ edit ] Illustration depicting areas affected by diabetic neuropathy Diabetic neuropathy affects all peripheral nerves including sensory neurons, motor[en.wikipedia.org] reflexes: Absent Associated with foot ulcers in chronic DM 7x increase Age: Middle-aged & elderly Location: Soles of feet Neuropathic osteoarthropathy : Frequency increased[neuromuscular.wustl.edu]

  • Guillain-Barré Syndrome

    F waves implicates nerve root involvement delayed/absent H reflex correlates with decreased/absent ankle reflex MRI cauda equina gandolinium enhancement in acute cases DIfferential[step2.medbullets.com] Acute Motor Axonal Neuropathy (AMAN) No sensory deficits Associated with epidemics following C. jejuni enteritis.[pedemmorsels.com] In 1986, Feasby et al identified an axonal type of GBS coupled with poor recovery characterised by severe Wallerian-like degeneration in the peripheral nerves at necropsy.[dx.doi.org]

  • Charcot Marie Tooth Disease

    Five months after the transient CNS symptoms, he finally developed signs and symptoms of neuropathy in the form of absent ankle reflexes.[pediatrics.aappublications.org] Charcot-Marie Tooth disease (CMT) encompasses several inherited peripheral motor-sensory neuropathies and is one of the most common inherited neuromuscular diseases.[ncbi.nlm.nih.gov] Ankle reflexes were bilaterally absent. Sequencing revealed a novel heterozygous c.712C T (p.R238C) mutation in the GJB1 gene.[ncbi.nlm.nih.gov]

  • Motor Neuron Disease

    In recent years, several reports show association of HIV infection with Amyotrophic Lateral Sclerosis - Syndrome, Motor Neuron Diseases and peripheral neuropathies.[ncbi.nlm.nih.gov] Several conditions have been reported to mimic motor neuron disease (MND) and misdiagnosis remains a common clinical problem.[ncbi.nlm.nih.gov] A possible viral etiology has been documented in the genesis of motor neuron disorders and acquired peripheral neuropathies, mainly due to the vulnerability of peripheral[ncbi.nlm.nih.gov]

  • Alcoholic Neuropathy

    Rarely if the neuropathy is severe patients may also develop peripheral weakness (motor symptoms).[braindiseases.info] Traumas, such as from motor vehicle accidents, falls or sports injuries, can sever or damage peripheral nerves.[mayoclinic.org] Patients develop a predominantly sensory neuropathy and have complaints of pain, burning, tingling, pins and needle sensation in the feet and sometimes in the finger tips.[braindiseases.info]

  • Hereditary Areflexic Dystasia

    Reflexes are normal in approximately two thirds of patients. In one study, ankle jerks were absent in 37.5%, and areflexia occurred in 12.5%.[emedicine.medscape.com] It includes several variants: Acute inflammatory demyelinative polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), and the Miller-Fisher syndrome (MFS).[neuropathology-web.org] Inflammation in peripheral nerve. The Guillain-Barré Syndrome(GBS) is not a single disease entity.[neuropathology-web.org]

  • Arsenic-Induced Polyneuropathy

    Proximal lower limb muscles were affected in 40% patients, rare upper limb involvement and ankle reflexes were absent in all with evidence of axonal degeneration and reinnervation[annalsofian.org] Peripheral neuropathy may also be caused by several heavy metals.[questdiagnostics.com] Diagnostic Approach The differential diagnosis of peripheral neuropathy is significantly narrowed by a focused clinical assessment that addresses several key issues ( Figure[aafp.org]

  • Diabetic Peripheral Neuropathy

    ankle reflexes.[f1000research.com] Diabetic peripheral neuropathy affects several types of nerves, including sensory, motor, and autonomic.[paindoctor.com] Ankle reflexes are usually reduced or absent, and knee reflexes may also be reduced in some cases.[clinical.diabetesjournals.org]

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