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129 Possible Causes for Absent Knee Reflex, Diplopia, Paresthesia

  • Guillain-Barré Syndrome

    In GBS, deep tendon reflexes in the legs, such as knee jerks, are usually lost. Reflexes may also be absent in the arms.[ninds.nih.gov] CASE REPORT: A 76-year-old woman was initially presented with diplopia, ophthalmoplegia, and ataxia, but she later developed weakness of limbs, respiratory failure, deterioration[ncbi.nlm.nih.gov] CONCLUSIONS A case of a rare variant of GBS is presented with facial diplegia and paresthesia and with unilateral facial palsy.[ncbi.nlm.nih.gov]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Knee and ankle jerk reflexes were absent. No abnormalities involving the cranial nerves were found.[omicsonline.org] Other features include dysphagia, diplopia, fatigue and clumsiness.[symptoma.com] The authors present the case of a 65-year-old woman who was admitted for paraparesis and paresthesias in the inferior limbs.[ncbi.nlm.nih.gov]

  • Diabetic Polyneuropathy

    Ankle reflexes are usually reduced or absent, and knee reflexes may also be reduced in some cases.[clinical.diabetesjournals.org] The patient with cranial nerve involvement usually has diplopia and single third, fourth, or sixth nerve weakness on examination but the pupil is spared.[health.am] Its symptoms are paresthesia, dysesthesia and pain.[ncbi.nlm.nih.gov]

  • Conversion Disorder

    Reflex testing was symmetrical and normal at the knee, ankle, and elbow. Light touch and proprioceptive sensation was absent on testing of all four extremities.[journals.lww.com] […] unresponsiveness may occur resembling fainting (syncope) or coma Sensory symptoms altered, reduced or absent skin sensations blindness, or altered/reduced vision double vision (diplopia[traumadissociation.com] Sensory disturbances may range from paresthesias (“peculiar” sensations) through hyperesthesias (hypersensitivity) to complete anesthesias (loss of sensation).[britannica.com]

  • Charcot Marie Tooth Disease

    Sensory loss is often identified when the doctor tests for deep tendon reflexes, such as the knee jerk, which are reduced or absent in CMT patients.[web.archive.org] He developed lower limb weakness in his teens, which progressed slowly and was accompanied by diplopia, bilateral hearing loss, and erectile dysfunction from his twenties.[ncbi.nlm.nih.gov] Patients also complain of numbness and tingling in their feet and hands, but paresthesias are not as common as in acquired neuropathies.[doi.org]

  • General Anesthesia

    She developed progressive tingling and numbness in her limbs after thyroidectomy under general anesthesia.[ncbi.nlm.nih.gov] Occasionally, a sensation of numbness or tingling may last for a few days or weeks after vaginal delivery even if epidural anesthesia was not given.[sparrow.org]

  • Caudal Spinal Cord Tumor

    […] migraine characterized by a visual aura followed by an often occipital headache and one or more of the following symptoms: dysarthria, vertigo, tinnitus, decreased hearing, diplopia[strokecenter.org] The numbness and paresthesia progress to a saddle distribution and extend into the lower extremity.[emedicine.medscape.com] Tiredness and weakness of the extremity, finger cramps, numbness, tingling, coldness of the hand, areas of hyperesthesia, muscle degeneration in the hand, a lump at the base[chiro.org]

  • Hyperkalemic Periodic Paralysis

    Distal legs Muscle size: Distal wasting Gait disorder (100%) Skeletal: Pes cavus (100%) Tendon reflexes: Reduced or Increased Ataxia: Sensory; 1 family Spasticity (50%): Legs Diplopia[neuromuscular.wustl.edu] Weakness can be accompanied by glove-and-stocking paresthesias.[ncbi.nlm.nih.gov] […] complete heart block, Mobitz type II second-degree atrioventricular block, ventricular tachycardia, ventricular fibrillation and asystole, muscle cramps, weakness, paralysis, paresthesias[jpharmacol.com]

  • Diabetic Neuropathy

    Ankle reflexes are usually reduced or absent, and knee reflexes may also be reduced in some cases.[clinical.diabetesjournals.org] The onset of a diabetic third nerve palsy is usually abrupt, beginning with frontal or periorbital pain and then diplopia.[en.wikipedia.org] (abnormal sensations), and patients complain of burning, tingling, aching, cold sensation, lancinating (sharp) pain, numbness, or pain from normal touch (allodynia), such[medscape.com]

  • Tabes Dorsalis

    The deep tendon reflexes are also diminished or absent; for example, the “knee jerk” or patellar reflex may be lacking ( Westphal’s sign ).[medical-institution.com] One year prior he noticed gradually progressive loss of vision in both eyes without any history of diplopia or ocular pain.[ncbi.nlm.nih.gov] A 39-year-old man presented with tingling paresthesia in the lower limbs, difficulty in walking, and loss of vision.[ncbi.nlm.nih.gov]

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