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20 Possible Causes for Absent Posterior Pituitary Bright Spot

  • Diabetes Insipidus

    This contrast enhanced dynamic MR shows an absent posterior pituitary bright spot on the pre-enhanced T1WI.[radiopaedia.org] T1 T1 sagittal images-Note absence of the posterior bright spot.[radiopaedia.org]

  • Pituitary Dwarfism

    The above case is a non-contrast MRI with an absent posterior pituitary bright spot (yellow arrow), an absent or thin stalk (green arrow), and an ectopic bright spot in the[roentgenrayreader.blogspot.com] posterior pituitary bright spot The exact cause of high T1 signal is uncertain and may relate to neurosecretory granules or high lipid content of the posterior pituitary[radiopaedia.org] An ectopic posterior pituitary lobe can also be seen in cases of pituitary stalk transection and septo-optic dysplasia and as an asymptomatic variant.[roentgenrayreader.blogspot.com]

  • Wolfram Syndrome

    Magnetic resonance imaging of the brain was diffuse cerebral degeneration along with absent posterior pituitary bright spot.[cjhr.org] The 24 h urine output, urine osmolality, serum osmolality, urine sodium levels, and formal water deprivation test along with absent posterior pituitary bright spot were suggestive[cjhr.org]

  • Pituicytoma

    MRI T1: isointense solid mass; posterior pituitary bright spot often absent T1 C (Gd): bright contrast enhancement T2: heterogeneous, hypointense to isointense DSA Pituicytomas[radiopaedia.org] CT Typically pituicytomas are homogeneously enhancing, either with the pituitary fossa or in the suprasellar region.[radiopaedia.org]

  • Autoimmune Hypophysitis

    T1 affected area is isointense with slight signal heterogeneity normal posterior pituitary bright spot may be absent 8 T1 C (Gd) can variably enhance, usually homogeneously[radiopaedia.org] MRI MRI, as is the case with other pituitary lesions, is the best modality for assessing this condition which appears as a pituitary region mass.[radiopaedia.org]

  • Panhypopituitarism

    ) pituitary stalk; absence of the posterior lobe in 9 cases: bright spot corresponding to an ectopic posterior lobe in 8 cases.[link.springer.com] The findings include: reduced pituitary size in all cases: partially (8 cases) or totally (2 cases) empty sella; thin (4 cases), partially visible (3 cases) or absent (2 cases[link.springer.com]

  • Central Diabetes Insipidus

    This contrast enhanced dynamic MR shows an absent posterior pituitary bright spot on the pre-enhanced T1WI.[radiopaedia.org] T1 T1 sagittal images-Note absence of the posterior bright spot.[radiopaedia.org]

  • Posterior Pituitary Disease

    pituitary bright spot should prompt the consideration of the following (noting it may be absent in normal patients): ectopic posterior pituitary central diabetes insipidus[radiopaedia.org] […] posterior aspect of the pituitary fossa normal measurements (decreasing size with age) 1,2 long axis: 1.2-8.5 mm short axis: 0.4-4.4 mm Related pathology The absence of posterior[radiopaedia.org]

  • Septo-Optic Dysplasia

    […] chiasm and optic nerves, APH, absence of posterior pituitary bright spot, absent infundibulum, dilatation of lateral ventricles 4 277T G Heterozygous Diabetes insipidus,[doi.org] , rudimentary stalk, atrophic bifrontal temporal region, nondeveloped optic chiasm 3 277T G Heterozygous GHD, diabetes insipidus Absent septum pellucidum, hypoplasia of optic[doi.org]

  • Hypothalamic Lesion

    posterior pituitarybright spot” Neurosarcoid Adult with stalk, meningeal lesions Other infectious/inflammatory lesions that can mimic sarcoid Wegener granulomatosis TB,[neupsykey.com] […] predominance in pineal gland) 10% “double” midline lesions (pineal & hypothalamus) DI, diencephalic syndrome, precocious puberty common Thick enhancing stalk, 3rd floor, absent[neupsykey.com]

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