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17 Possible Causes for Acanthosis Nigricans, Supraclavicular Fat Pads

  • Obesity

    Obesity is a chronic disease that may lead to skin problems, including acanthosis nigricans, skin tags, hyperandrogenism, striae distensae, plantar hyperkeratosis, and candidal[ncbi.nlm.nih.gov] Complications of obesity include cardiovascular risks, hypertension, dyslipidemia, endothelial dysfunction, type 2 diabetes mellitus and impaired glucose tolerance, acanthosis[ncbi.nlm.nih.gov] Moreover, obesity is implicated in a wide spectrum of dermatologic diseases, including acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism and hirsutism[ncbi.nlm.nih.gov]

  • Morbid Obesity

    Clinical findings were generalised obesity with a body mass index 95th centile, acanthosis nigricans of the neck, arms with self inflicted lesions, deep-set eyes, straight[ncbi.nlm.nih.gov] Obesity is implicated in a wide spectrum of dermatological diseases, including acanthosis nigricans, acrochordons, keratosis pilaris, striae distensae, adiposis dolorosa,[o-wm.com]

  • Cushing's Disease

    Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com] fat pads (buffalo hump) Usually, very slender distal extremities and fingers Muscle wasting and weakness are present.[merckmanuals.com] At baseline and at months 6 and 12, a reviewer at each site assessed patients for signs of hypercortisolism (facial rubor and supraclavicular and dorsal fat pads) by scoring[nejm.org]

  • Bronchogenic Carcinoma

    nigricans: Insulin resistance leads to hyperinsulinemia which in turn stimulates proliferation of keratinocytes (containing melanin) and fibroblasts H ypercalciuria (Renal[epomedicine.com] nigricans, and hypertrophic osteoarthropathy (Example: clubbing of fingers).[histopathology-india.net] nigricans thrombophlebitis : adenocarcinoma subtype Treatment and prognosis Treatment and prognosis vary not only with stage but also with cell type.[radiopaedia.org]

  • Iatrogenic Cushing's Disease

    He did not have striae, edema, acanthosis nigricans, or hypertrichosis. Laboratory evaluation revealed a cortisol level of am , and the diagnosis of ICS was made.[pediatrics.aappublications.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com] Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com]

  • Cushing Syndrome

    […] moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis[radiopaedia.org] […] hump"), increased supraclavicular fat pads, and white abdominal striae.[ncbi.nlm.nih.gov] Insulin resistance is accompanied by skin changes such as acanthosis nigricans in the axilla and around the neck, as well as skin tags in the axilla.[en.wikipedia.org]

  • ACTH-Independent Cushing Syndrome

    […] moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis[radiopaedia.org] . - Steroid acne - Acanthosis nigricans, which is associated with insulin resistance and hyperinsulinism, may be present.[aippg.net] Presentation Truncal obesity, supraclavicular fat pads, buffalo hump, weight gain. Facial fullness, moon facies, facial plethora. Proximal muscle wasting and weakness.[patient.info]

  • ACTH-Dependent Cushing Syndrome

    […] moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis[radiopaedia.org] Case: A 26-year-old male patient presented with moon face, purplish striae, supraclavicular fat pads and proximal muscle weakness.[endocrine-abstracts.org] pad (buffalo hump); supraclavicular fat pads; facial fullness (moon face) Reproductive system- menstrual irregularity; infertility Psychiatric effects- depression (62%),[dundeemedstudentnotes.wordpress.com]

  • Ovarian Stromal Hyperthecosis

    nigricans syndrome.[malacards.org] She had moon facies with increased supraclavicular fat pads.[arcfertility.com] Clinically, aside from central obesity, the skin disorder acanthosis nigricans can also herald this MSX syndrome.[palpath.com]

  • Cushing Syndrome due to Macronodular Adrenal Hyperplasia

    […] moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis[radiopaedia.org] Presentation Truncal obesity, supraclavicular fat pads, buffalo hump, weight gain. Facial fullness, moon facies, facial plethora. Proximal muscle wasting and weakness.[patient.info] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org]

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