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1,613 Possible Causes for Accelerated Growth, Caused by Mutation in the DMX-like 2 Gene (DMXL2), Small Testicular Volume

Did you mean: Accelerated Growth, Caused by Mutation in the DMX-like 2 Gene (DMXL2, Small Testicular Volume

  • Klinefelter Syndrome

    Clinical examination showed tall stature and progressive growth acceleration between 5 and 7 years, and one of them had hypoplastic scrotum with monolateral cryptorchidism[ncbi.nlm.nih.gov] They concluded that the decline in serum testosterone may be related to the small testicular volume and Leydig cell loss near the scars after the procedures.[web.archive.org] Most symptoms are first seen at puberty when androgen deficiency becomes evident as testes begin to shrink and harden, gynecomastia develops, and accelerated growth is observed[helicase.pbworks.com]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Polyendocrine - Polyneuropathy Syndrome

    Accelerate your rare disease diagnosis with us Learn more Rare diseases associated to DMXL2 gene Here you will find a list of rare diseases related to the DMXL2.[mendelian.co] testicular volume SKIN, NAILS, HAIR: [Hair]; Partial frontal alopecia NEUROLOGIC: [Central nervous system]; Mental retardation, moderate; Dysarthria; Dystonia; Ataxia; Pyramidal[findzebra.com] […] alterations may also develop some of the following symptoms and phenotypes: Not very common - Between 30% and 50% cases Progressive hearing impairment Polyneuropathy Postnatal growth[mendelian.co]

  • Precocious Puberty

    A 7-year-old Indian girl presented with symptoms of excessive development of breasts, early menarche, growth of pubic hairs, accelerated growth and abdominal distension.[ncbi.nlm.nih.gov] If both testes are prepubertal in volume, this points toward CAH or an adrenal tumor or possibly a small testicular tumor.[glowm.com] Early puberty accelerates growth. These children may initially be considerably taller than their peers.[emedicine.com]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Klinefelter Syndrome with XY/XXY Mosaic

    Most symptoms are first seen at puberty when androgen deficiency becomes evident as testes begin to shrink and harden, gynecomastia develops, and accelerated growth is observed[helicase.pbworks.com] These features would include first and foremost small firm testes (low testicular volume), tall slender body habitus, and in some cases breast enlargement (gynecomastia) and[dermatologyadvisor.com] Boys with Klinefelter's syndrome have a somewhat greater height growth acceleration than other boys from about 4-5 years of age.[klinefelters.org]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Familial Male-Limited Precocious Puberty

    Patients have accelerated growth, early development of secondary sexual characteristics and reduced adult height.[rarediseases.info.nih.gov] Prader orchidometer is used to measure testicular volume testicular length testicular area testicular density Q 12. gonadotropin independent causes of precocious puberty in[natboardmcqs.com] Affected males usually show evidence of virilization and accelerated linear growth by 1 to 3 years of age.[journals.lww.com]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Morbid Obesity

    Morbid obesity is associated with liver pathology, most commonly non-alcoholic steatohepatitis (NASH) leading to cirrhosis. However, the morbid obesity impedes qualification for organ transplantation. We present a case report of a 56-year-old woman who underwent bariatric procedure followed by liver transplantation[…][ncbi.nlm.nih.gov]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2) Small Testicular Volume
  • Central Precocious Puberty

    At the age of 1 year, our patient presented with increased testicular volume for his age, bone age advancement and growth acceleration.[ncbi.nlm.nih.gov] growth rate and advancement of skeletal age.[ncbi.nlm.nih.gov] […] of body hair Accelerated growth There are two types of precocious puberty: Central precocious puberty (CPP).[rileychildrens.org]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2) Small Testicular Volume
  • Aromatase excess syndrome

    Acceleration of bone growth becomes evident before 10 years of age.[doi.org] Lastly, although testis volume appears somewhat small, fertility (spermatogenesis) is normally preserved in the three types.[academic.oup.com] Males present with heterosexual precocious puberty which manifests with pre- or peripubertal onset of gynecomastia, premature growth spurt, accelerated bone maturation resulting[orpha.net]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Hypogonadism

    Currently, replacing testosterone to physiologic levels is not thought to cause new prostate cancer or accelerate growth or spread of localized prostate cancer.[msdmanuals.com] […] testes – volume typically 3 Lack of secondary sexual characteristics Most common cause is Klinefelter syndrome Postpubertal hypogonadism Sexual – decreased libido, erectile[arupconsult.com] During this time, body odor develops, oiliness of the skin and hair increase, acne develops, accelerated growth spurts occur, and pubic, early facial, and axillary hair grows[ncbi.nlm.nih.gov]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2)
  • Adrenogenital Syndrome

    Along with reduction of urinary output of androgens, growth was moderately retarded, but when cortisone dosage was lowered output of androgens increased and marked acceleration[pediatrics.aappublications.org] […] of growth, including skeletal maturation, occurred.[pediatrics.aappublications.org] These episodes may have been due to accelerated release of desoxycorticosterone from implanted DOCA pellets. Received November 21, 1956. Accepted February 6, 1957.[pediatrics.aappublications.org]

    Missing: Caused by Mutation in the DMX-like 2 Gene (DMXL2) Small Testicular Volume