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15 Possible Causes for Accelerated Growth, Luteinizing Hormone Low, Testicular Biopsy Abnormal

  • Klinefelter Syndrome

    Clinical examination showed tall stature and progressive growth acceleration between 5 and 7 years, and one of them had hypoplastic scrotum with monolateral cryptorchidism[ncbi.nlm.nih.gov] Endocrinological examination revealed a high growth hormone (GH) concentration, low testosterone concentration, and high follicle-stimulating hormone and luteinizing hormone[ncbi.nlm.nih.gov] Testicular biopsies of KS infants and boys demonstrated decreased or absent germ cells and abnormal seminiferous tubules ( 16 , 50 – 52 ).[dx.doi.org]

  • Central Precocious Puberty

    At the age of 1 year, our patient presented with increased testicular volume for his age, bone age advancement and growth acceleration.[ncbi.nlm.nih.gov] Although basal levels of luteinizing hormone and follicle-stimulating hormone are low, similar to what is expected in the pre-pubertal period, testosterone levels are high[ncbi.nlm.nih.gov] A testicular biopsy was not done. Our patient was treated with four cycles of preoperative chemotherapy (cisplatin, alternating with carboplatin/dox-orubicin).[cyberleninka.org]

  • Leydig Cell Tumor

    He had pubic hair (Tanner stage PH2), enlarged testicular volume (Tanner stage G2: left testis 4 mL, right testis 6 mL) and an accelerated growth velocity.[frontiersin.org] Serum levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were inappropriately low for a post-menopausal woman, with high levels of estradiol.[scielo.br] growth and bone maturation, may develop after surgical therapy. 8 Radical inguinal orchiectomy is still recommended as standard treatment.[pediatrics.aappublications.org]

  • Hypogonadism

    Currently, replacing testosterone to physiologic levels is not thought to cause new prostate cancer or accelerate growth or spread of localized prostate cancer.[msdmanuals.com] hormone ( 9.4 mU/mL)], secondary (low total testosterone, low/normal luteinizing hormone), primary (low total testosterone, elevated luteinizing hormone) and compensated[ncbi.nlm.nih.gov] If tests confirm that you have low testosterone, further testing can determine if a testicular disorder or a pituitary abnormality is the cause.[mayoclinic.org]

  • Anorchia

    […] linear growth (and bone age maturation), deepening of the voice, acne and a muscular body habitus.[pediatricurologybook.com] Tests include testosterone levels (low); follicle stimulating hormone and luteinizing hormone levels (elevated); X,Y karyotype; ultrasound or magnetic resonance imaging showing[bionity.com] Testicular biopsy is rarely indicated (special fixative required).[rcpa.edu.au]

  • Gonadoblastoma

    Various studies suggest that TSPY accelerates cell proliferation and growth, and promotes tumorigenesis.[ncbi.nlm.nih.gov] Serum testing revealed primary hypogonadism pattern, elevated follicle-stimulating hormone and luteinizing hormone with low concentrations of estradiol and testosterone.[ncbi.nlm.nih.gov] Subsequent testicular biopsy and histopathological examination showed intratubular malignant germ cells in the testicular tubules.[ncbi.nlm.nih.gov]

  • Primary Male Hypogonadism

    Currently, replacing testosterone to physiologic levels is not thought to cause new prostate cancer or accelerate growth or spread of localized prostate cancer.[merckmanuals.com] Patients who have demonstrably low levels of luteinizing hormone often need some form of Testosterone Replacement Therapy in order to preserve healthy function.[hgh.tv] These studies may include: Hormone testing Semen analysis Pituitary imaging Genetic studies Testicular biopsy Testosterone testing also plays an important role in managing[nchmd.org]

  • Feminization

    The clinical findings were gynecomastia and accelerated linear growth and bone maturation.[ncbi.nlm.nih.gov] Incisional biopsy of abnormal gonads is important, but the diagnosis of testicular feminization must be confirmed by appropriate laboratory tests.[ncbi.nlm.nih.gov]

  • Hypocupremia

    During this time, body odor develops, oiliness of the skin and hair increase, acne develops, accelerated growth spurts occur, and pubic, early facial, and axillary hair grows[ncbi.nlm.nih.gov] Etiology of hypogonadism For men with confirmed low testosterone levels, serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels should be measured to[ncbi.nlm.nih.gov] If tests confirm that you have low testosterone, further testing can determine if a testicular disorder or a pituitary abnormality is the cause.[mayoclinic.org]

  • Hypokalemic Periodic Paralysis

    During this time, body odor develops, oiliness of the skin and hair increase, acne develops, accelerated growth spurts occur, and pubic, early facial, and axillary hair grows[ncbi.nlm.nih.gov] Etiology of hypogonadism For men with confirmed low testosterone levels, serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels should be measured to[ncbi.nlm.nih.gov] If tests confirm that you have low testosterone, further testing can determine if a testicular disorder or a pituitary abnormality is the cause.[mayoclinic.org]