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1,216 Possible Causes for acid, activation, amino, biosynthetic, for, nonribosomal, peptide, process

Did you mean: acne, amotivation, aging, biosynthetic, for, nonribosomal, peptide, proteus

  • Novobiocin

    Nalidixic acid (2%) or novobiocin (2% or 5%) in methylcellulose were applied twice daily under occlusion, and methylcellulose alone was used as a control.[ncbi.nlm.nih.gov] To determine if novobiocin and the 11-mer shared a common allosteric binding site, a biologically-active analog of the 11-mer peptide ([Bio-DOPA]11-mer) was chemically cross-linked[ncbi.nlm.nih.gov] Upon oxidation this intermediate will spontaneously lactonize to form the aromatic ring B and lose NovH in the process.[en.wikipedia.org] The amino acid released was (3R,2S)-3-OH-Tyr by comparison with authentic standards.[ncbi.nlm.nih.gov] Hypothetical biosynthetic pathway of novobiocin. Roman numerals refer to the putative assignments of genes identified in the biosynthetic reactions (see Table 1 ).[doi.org] One analog retains LptB-stimulatory activity but is unable to inhibit DNA gyrase.[doi.org] Abstract ABSTRACT: The bicyclic coumarin ring in the aminocoumarin natural product antibiotics that target bacterial DNA gyrase is assembled from tyrosine by nonribosomal[citeseerx.ist.psu.edu] Abstract The bicyclic coumarin ring in the aminocoumarin natural product antibiotics that target bacterial DNA gyrase is assembled from tyrosine by nonribosomal peptide synthetase[doi.org]

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  • Streptococcus Mutans

    These results indicate that some sRNAs are specially induced at acid stress conditions, involving acid adaptation, and provide a new insight into exploring the complex acid[ncbi.nlm.nih.gov] CSP (competence-stimulating peptide) pheromone.[doi.org] Caries ecology revisited: microbial dynamics and the caries process . Caries Res 42: 409 - 418 . Google Scholar Crossref Medline ISI Takahashi, N, Yamada, T ( 1996 ).[doi.org] Human β-defensin-3 (HBD3) is a 45-amino-acid natural antimicrobial peptide that has broad spectrum antimicrobial activity against bacteria and fungi.[ncbi.nlm.nih.gov] Bioinformatic characterization of 169 publically available genomes of S. mutans from human dental caries revealed a surprisingly rich source of natural product biosynthetic[ncbi.nlm.nih.gov] active pcomX activity in high cell density areas within the biofilm population.[ncbi.nlm.nih.gov] Prior studies of the biofilm formation process by fluorescence microscope, scanning electron microscope, or spectroscope have roughly divided the mechanism into three stages[ncbi.nlm.nih.gov] […] phosphofructokinase, FruK, display changes in expression of a large number of genes encoding transcriptional regulators, enzymes required for energy metabolism, biofilm development, biosynthetic[ncbi.nlm.nih.gov]

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  • Lactococcus Lactis

    The lactic acid productivity was highest between 33  C and 35  C and at pH 6.[doi.org] This paper presents a food grade expression system for an antifreeze peptide SF-P using L. lactis as a host, and shows that the intracellular expression of antifreeze peptide[ncbi.nlm.nih.gov] Under these conditions, almost 10% of the 900 samples processed yielded viable phages.[doi.org] […] catabolism of amino acids.[bmcmicrobiol.biomedcentral.com] Appl Environ Microbiol 57:3535–3540 Google Scholar Stormer FC (1975) 2,3-Butanediol biosynthetic system in Aerobacter aerogenes .[link.springer.com] They also showed inhibitory activities on IL-6-induced STAT3 activation, and showed the different in activity according to the presence of a phenylalanine residue, hydroxyl[ncbi.nlm.nih.gov] Further niche-specific differences are found in genes for defense (nisin biosynthesis), stress response (nonribosomal peptide synthesis and various transporters), and exopolysaccharide[ncbi.nlm.nih.gov] Due to its important applications, simple metabolism and limited biosynthetic capabilities, its genome has been sequenced to help researchers understand genes that are responsible[microbewiki.kenyon.edu]

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  • Bacillus Subtilis

    Although various aminoacyl-tRNA synthetases can charge their cognate tRNAs with amino acid analogs, there has been no known displacement of any canonical amino acid from the[ncbi.nlm.nih.gov] The antimicrobial peptide, tentatively named AMP IC-1, was purified, characterized, and compared to BSAP-254, another peptide which was previously recovered from traditionally[ncbi.nlm.nih.gov] Abstract We previously reported the insertion process of the ferrous ion into the protoporphyrin IX from the side of the residue His-183 (J. Inorg.[ncbi.nlm.nih.gov] Ancestral biosynthetic AAT-fold ADC appears to be limited to firmicute bacteria.[ncbi.nlm.nih.gov] In addition, the cultures showed cellulase activity in carboxy methyl cellulose medium (1.5-1.8mg of reducing sugar24h(-1)ml(-1)) and amylase activity in vitro.[ncbi.nlm.nih.gov] Antimicrobial activity analysis combined with the results of amplifying genes encoding for polyketide synthetase and nonribosomal peptide synthetase showed that seaweed-associated[ncbi.nlm.nih.gov] In this study, we analyzed the activity of probiotic strain B. subtilis 3 against the influenza virus.[ncbi.nlm.nih.gov] Alamethicin is a well-studied antimicrobial peptide (AMP) that kills Gram-positive bacteria. It forms narrow, barrel-stave pores in planar lipid bilayers.[ncbi.nlm.nih.gov]

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  • Streptococcus Lactis

    The lactic acid productivity was highest between 33  C and 35  C and at pH 6.[doi.org] […] results from comparative genomics (see references above) this resulted in L. lactis losing or down-regulating genes which are dispensable in milk and the up-regulation of peptide[en.wikipedia.org] Under these conditions, almost 10% of the 900 samples processed yielded viable phages.[doi.org] Whereas L. bulgaricus has lost most of its amino acid biosynthesis capacity, S. thermophilus retains its ability to synthesize all amino acids, except histidine ( 33 ).[doi.org] However, strain KF147 clearly has an internal deletion in parts of the nisB and nisC genes, which should lead to inactivation of the encoded nisin biosynthetic enzymes.[doi.org] The superoxide dismutase (SOD) activities in the liver, brain and erythrocytes of 75-week-old mice significantly decreased compared with those aged 10 weeks.[ncbi.nlm.nih.gov] In cell populations, the total mitochondrial activity is related to the number of living cells.[doi.org] Lars Axelsson , Lactic Acid Bacteria , Lactic Acid Bacteria , 10.1201/9780824752033.ch1 , (2009) .[doi.org]

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  • Pseudomonas

    KEYWORDS: Beta-D-glucan; High cortisol state; Immunocompromised host; Partially acid-fast[ncbi.nlm.nih.gov] WSA uses trypsin digestion of whole phage particles, followed by reversed-phase HPLC and gas-phase fractionation of the complex peptide mixture prior to MS.[doi.org] Each processing plant was visited at least three times.[doi.org] In the present study we were able to improve LuxR's affinity and detection limit for 2-AA by genetic modification of three amino acids within the binding pocket of the receptor[ncbi.nlm.nih.gov] At the transcriptional level, several secondary metabolites positively regulate the expression of their own biosynthetic genes.[doi.org] […] we showed has no antimicrobial activity.[ncbi.nlm.nih.gov] Walsh , N-Acylation during Glidobactin Biosynthesis by the Tridomain Nonribosomal Peptide Synthetase Module GlbF , Chemistry & Biology , 17 , 10 , (1077) , (2010) .[doi.org] Consequently, less abundant proteins or peptides migrating between visible bands were not overlooked.[doi.org]

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  • Polyphenol

    To this aim, in a 1st step just fatty acids were extracted and in a 2nd one the polyphenols.[ncbi.nlm.nih.gov] It has been reported that the aglycone form of Oleuropein (OleA) interferes in vitro and in vivo with amyloid aggregation of a number of proteins/peptides involved in amyloid[ncbi.nlm.nih.gov] Raw and processed breadfruit had higher hydrolysis curves than raw and processed beans with the amylolysis level in raw breadfruit close to that of white bread.[ncbi.nlm.nih.gov] It is, for example, the case for many alkaloids derived from the phenylalanine/tyrosine amino acids.[groupepolyphenols.com] […] review highlights recently unveiled biosynthetic mechanisms to generate highly diverse and complex molecules.[ncbi.nlm.nih.gov] How do they express their biological activity? Are they really valuable for disease prevention? Can they be used to develop new pharmaceutical drugs?[ncbi.nlm.nih.gov] Bode , A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides , Nat. Prod. Rep. , 10.1039/C3NP70081J , 31 , 2 , (154-159) , (2014) .[doi.org] Economics, Műegyetem rkp. 3, Budapest 1111, Hungary. 5 Institute of Chemistry, Eötvös Loránd University, Budapest 112, POB 32, H-1518, Hungary. 6 MTA-ELTE Research Group of Peptide[ncbi.nlm.nih.gov]

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  • 6-Aminocaproic Acid

    Abstract In the biosensor construction, 3-mercaptopropionic acid (3-MPA) and 6-aminocaproic acid (6-ACA) were used for forming self-assembled monolayer (SAM) on a gold disc[ncbi.nlm.nih.gov] LifeTein can attach the PEGs to peptides.[lifetein.com] A process for the preparation of dyes DE1233410B ( en ) 1967-02-02 A process for the preparation of substituted Phenylnitroaethanolen DE1149700B ( en ) 1963-06-06 A process[google.com.na] The biomedical properties of novel biodegradable copoly(amino acid)s based on 6-aminocaproic acid and L-proline were analyzed in this article.[ncbi.nlm.nih.gov] In some embodiments, the 6-aminohex-2-enoic acid biosynthetic pathway is the same as the aminocaproic biosynthetic pathway with omission of the last enzymatic step.[google.de] […] the Invention The present invention is generally related to a method of making 6-aminocaproic acid, and more particularly to a method of making 6-aminocaproic acid as an active[google.sr] 6-aminocaproic acid from 5-formyl valeri C acid US15/599,314 US20180100172A1 ( en ) 2008-03-11 2017-05-18 Preparation of 6-aminocaproic acid from 5-formyl valeric acid Related[google.co.in] -1-oxohexyl)amino]hexanoic Acid; Impurity: CAS Number: 2014-58-6 Alternate CAS #: NA Molecular form.: C₁₂H₂₄N₂O₃ Appearance: White to Off-White Solid Melting Point: 172 C[trc-canada.com]

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  • Ergot Alkaloid

    In addition, in DF lysergic acid was found, which has not been reported yet as ingredient of A. nervosa.[ncbi.nlm.nih.gov] RESULTS: We have identified the obligatory peptidic intermediates in D-lysergyl peptide synthesis and the sequential order of their formation.[ncbi.nlm.nih.gov] For example, these older processes used aqueous ethanol or methanol (see DE 47 315 and DP 697 760 ), newer processes used chlorinated 697 760 ), newer processes used chlorinated[google.com] The 3 Amino acids vary. 20% amino alcohol derivative, first to be identified in 1935.[quizlet.com] Identification of nine common genes between them suggests the possible role of these genes in the early part of the ergot alkaloid biosynthetic pathway.[uknowledge.uky.edu] activated human peripheral blood mononuclear cells (PBMC) was investigated.[ncbi.nlm.nih.gov] Peptide formation involves the same processes seen in the nonribosomal biosynthesis of peptides, and involves ATP-mediated activation of the amino acids prior to attachment[biocyclopedia.com] This fundamental biosynthetic capability may have been developed differently in a few lineages (e.g., in the Clavicipitaceae, A. fumigatus , and perhaps other fungi) under[academic.oup.com]

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  • Arginine

    Taurine, glutamine and arginine are examples of amino acids which have become increasingly popular as ingredients in dietary supplements and functional foods and beverages[ncbi.nlm.nih.gov] These mutations are either in the signal peptide or scattered throughout the neurophysin II domain.[ncbi.nlm.nih.gov] Arginine methylation has emerged as a widespread and reversible protein modification with the potential to regulate a multitude of cellular processes, but its function is[ncbi.nlm.nih.gov] Optimization of the L -arginine biosynthetic pathway flux To further optimize L -arginine biosynthetic pathway flux in the AR4 strain, the Ncgl1221 gene, which is known to[nature.com] This peptide exhibited higher anticancer activity and penetrability against solid tumor cells than lycosin-I.[ncbi.nlm.nih.gov] SRSF4 is associated with many physiological and pathological processes and has applications in the diagnosis and prognosis of specific diseases.[ncbi.nlm.nih.gov] Among all peptides, cyclic [HR]₄ peptide was able to improve the delivery of a cell impermeable fluorescence-labeled phosphopeptide by two-fold.[ncbi.nlm.nih.gov] These observations suggest that folic acid supplementation may enhance cellular methylation capacity under a low methionine status.[ncbi.nlm.nih.gov]

    Missing: for nonribosomal