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182 Possible Causes for Acidosis, Glucose Increased, Variable Hypoglycemia

  • Glycogen Storage Disease Type 6

    Individuals with GSD VI typically exhibit hepatomegaly, growth retardation, and variable but mild episodes of fasting hypoglycemia and hyperketosis during early childhood.[emedicine.com] In less common forms of the disease, symptoms (particularly hypoglycemia and hepatomegaly) may be severe and patients may even develop metabolic (lactic) acidosis after meals[symptoma.com] Oral galactose and fructose fail to increase glucose levels but plasma lactic acid levels increase.[patient.info]

  • Diabetic Ketotic Coma

    Glycemic variability: A strong independent predictor of mortality in critically ill patients. Crit Care Med 2008;36:3008-3013. Moore C, Woollard M.[ahcmedia.com] Clinically, they differ only by the degree of dehydration and the severity of metabolic acidosis.[endocrinologyadvisor.com] As the blood glucose levels increase in HHS, the body tries to get rid of the excess glucose by increased urinary volume.[star2.com]

  • Islet Cell Tumor

    PNETs are functional or non-functional tumors and represent a heterogeneous group of neoplasms with extremely variable clinical behavior.[ec.bioscientifica.com] Most cases of NICTH and lactic acidosis have been described in the adult population.[ncbi.nlm.nih.gov] Glucagon also plays a role in the amount of glucose in the bloodstream, and in this case, it increases the amount of glucose present.[uhhospitals.org]

  • Hyperglycemia

    Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit. Pediatrics 2006;118:173-9.[saripediatri.org] Affected patients usually present with metabolic crisis including hypoglycemia, acidosis, ketonuria, and hyperuricemia.[ncbi.nlm.nih.gov] The patient s blood glucose increased up to 250 mg/dl on a glucose perfusion rate of 6 mg/kg/min after the second day of cooling.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Associated Complications: CNS : retinopathy, peripheral neuropathies, and autonomic neuropathy (decreased heart rate variability, orthostatic hypotension, gastroparesis,[openanesthesia.org] It presents with asymptomatic hyperkalemia along with hyperchloraemic metabolic acidosis without significant renal function impairment.[ncbi.nlm.nih.gov] As the blood glucose level increases, so also does the glucose content in the aqueous humor.[aao.org]

  • Diabetes Mellitus Type 1

    There was no significant between-group difference in the number of severe hypoglycemia events. (p 0.1276).[ncbi.nlm.nih.gov] Postprandial glucose levels increased more markedly in T1DM (to 22.1 1.4 vs. 11.2 0.6mmol/L) while insulin levels increased only in T2DM (from 24.4 4.4 to 68.8 12.3μU/mL).[ncbi.nlm.nih.gov] acidosis.[ncbi.nlm.nih.gov]

  • Diabetic Ketoacidosis

    PURPOSE: To compare one vs. two bag system with respect to blood glucose variability (BGV), time for resolution of acidosis and incidence of hypoglycemia, hypokalemia, and[ncbi.nlm.nih.gov] Metabolic acidosis in an infant requires a broad differential. Rasburicase should be considered in hyperuricemia and DKA.[ncbi.nlm.nih.gov] This review reveals the possible pathophysiology with a chain of metabolic adaptions to decrease plasma glucose and increase plasma ketone bodies through pancreas, kidney,[ncbi.nlm.nih.gov]

  • Alcoholic Ketoacidosis

    The pivotal variable appears to be a relative deficiency of insulin.[emedicine.com] These two conditions should be considered when using the osmolal gap to design therapy (for example, hemodialysis) in the setting of anion gap metabolic acidosis and suspected[ncbi.nlm.nih.gov] Patients: Twenty-three patients with lactic acidosis, 19 with alcoholic ketoacidosis, and 10 randomly selected controls.[annals.org]

  • Diabetes Mellitus Type 2

    The choice of glycemic target also depends on consideration of other variables, such as risk for hypoglycemia, weight gain, and other drug-related adverse effects, as well[doi.org] Lactic acidosis is a serious side effect seen with metformin use, and while the incidence of lactic acidosis is similar to other oral antidiabetics, metformin is not recommended[ncbi.nlm.nih.gov] glucose concentration and associated glycemia/HbA1c values, with the strength of the correlation increasing for higher glycemia/HbA1c values.[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 1

    1 The variable clinical phenotype of three patients with hepatic glycogen synthase deficiency. ( 28245189 ) 2017 2 Pediatric patient with hyperketotic hypoglycemia diagnosed[malacards.org] Treatment of mice with S4048 resulted in an 60% reduction in blood glucose, increased hepatic glycogen and triacylglycerol (triglyceride) content, and a markedly enhanced[ncbi.nlm.nih.gov] Treatment of acute metabolic acidosis episodes [ edit ] The most significant acute problem in childhood is a vulnerability to episodes of metabolic acidosis precipitated by[en.wikipedia.org]

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