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14 Possible Causes for Acquired Spherocytosis, Bone Marrow with Increased Iron Stores, Congenital Nonspherocytic Hemolytic Anemia

  • Hereditary Spherocytosis

    Hereditary spherocytosis (HS) is the third most common yet most frequently underrecognized, congenitally acquired hemolytic disease of the neonate.[ncbi.nlm.nih.gov] It should be emphasized, however, that decreased membrane surface area is a hallmark of spherocytes of various origins and may also be transiently observed in acquired spherocytosis[bloodjournal.org] Hereditary spherocytosis is caused by a defect of one or more erythrocyte membrane proteins, which leads to an increased rate of destruction of circulating red blood cells[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    D58.1 Hereditary elliptocytosis D58.2 Other hemoglobinopathies D58.8 Other specified hereditary hemolytic anemias D58.9 Hereditary hemolytic anemia, unspecified D59 Acquired[icd10data.com] Acquired Immune: Isoimmune: haemolytic disease of newborn , blood transfusion reaction.[patient.info] […] autoimmune D59.1 ICD-10-CM Codes Adjacent To D59.1 D57.812 Other sickle-cell disorders with splenic sequestration D58 Other hereditary hemolytic anemias D58.0 Hereditary spherocytosis[icd10data.com]

  • Acquired Toxic Hemolytic Anemia

    Abnormalities include hereditary cell membrane disorders (eg, hereditary spherocytosis ), acquired cell membrane disorders (eg, paroxysmal nocturnal hemoglobinuria ), disorders[msdmanuals.com] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[diagnose-me.com] D58.1 Hereditary elliptocytosis D58.2 Other hemoglobinopathies D58.8 Other specified hereditary hemolytic anemias D58.9 Hereditary hemolytic anemia, unspecified D59 Acquired[icd10data.com]

  • Congenital Hemolytic Anemia

    Definition / general Congenital (hereditary spherocytosis, sickle cell) or acquired Acquired cases are usually due to deposition of immune complexes on red blood cell membranes[pathologyoutlines.com] This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding[en.wikipedia.org] Abnormalities include hereditary cell membrane disorders (eg, hereditary spherocytosis ), acquired cell membrane disorders (eg, paroxysmal nocturnal hemoglobinuria ), disorders[merckmanuals.com]

  • Pyruvate Kinase Deficiency

    Notable amongst the acquired forms are autoimmune hemolytic anemia, mechanical hemolytic anemia and paroxysmal nocturnal hemoglobinuria (PNH).[fcarreras.org] In this later group of "congenital nonspherocytic hemolytic anemias" splenectomy has often been performed but usually does not produce a clinical cure.[nejm.org] congenital nonspherocytic hemolytic anemia that has material basis in homozygous or compound heterozygous mutation in the PKLR gene on chromosome 1q22 pyruvate kinase deficiency[wikidata.org]

  • Congenital Heinz Body Hemolytic Anemia

    Hereditary spherocytosis. acquired immune hemolytic anemia.[labpedia.net] nonspherocytic hemolytic anemia * (n) 先天性貧血 P614 ** せんてんせいひんけつ PubMed, Scholar, Google, WikiPedia congenital anemia * (n*) 先天性溶血性貧血 *** せんてんせいようけつせいひんけつ シソーラス PubMed, Scholar[lsd-project.jp] Abnormalities include hereditary cell membrane disorders (eg, hereditary spherocytosis ), acquired cell membrane disorders (eg, paroxysmal nocturnal hemoglobinuria ), disorders[merckmanuals.com]

  • Waters-West Syndrome

    […] host disease Noonan syndrome Factor V Leiden thrombophilia Acquired Von Willebrand syndrome Loeys-Dietz syndrome type 2 Hemochromatosis type 3 Loeys-Dietz syndrome type 3 Acquired[checkrare.com] Increased metabolic requirements, neoplasia. PATHOLOGY: Microcytic, hypochromic anemia. Low serum iron. Bone-Marrow will show absence of iron.[kumc.edu] MalaCards based summary : Hemolytic Anemia, Lethal Congenital Nonspherocytic, with Genital and Other Abnormalities, is also known as hemolytic anemia lethal congenital nonspherocytic[malacards.org]

  • Acquired Hemolytic Anemia

    Definition / general Congenital (hereditary spherocytosis, sickle cell) or acquired Acquired cases are usually due to deposition of immune complexes on red blood cell membranes[pathologyoutlines.com] Assuming the bone marrow is normal and there are sufficient erythropoeitin and iron stores, acute anemia (ie. hemolysis or blood loss) should increase the retic % to 4-6%[errolozdalga.com] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[diagnose-me.com]

  • Congenital Dyserythropoietic Anemia

    […] dyserythropoiesis (myelodysplastic syndrome, acute erythroid leukemia), hemolytic anemias (hereditary spherocytosis) or microcytic anemias (thalassemias and iron deficiency[rarediseases.info.nih.gov] Iron stores were increased although ring sideroblasts were absent.[ncbi.nlm.nih.gov] , type I Congenital dyserythropoietic anemia, type II Congenital dyserythropoietic anemia, type III Congenital nonspherocytic hemolytic anemia due to inborn error of metabolism[icd9data.com]

  • Normocytic Normochromic Anemia

    Classification of the Hemolytic Disorders (Open Table in a new window) Hereditary Acquired Intracorpuscular defect Hereditary spherocytosis Hereditary elliptocytosis Hemoglobinopathies[emedicine.medscape.com] Bone marrow iron stores are usually increased. Ferritin (an acute phase reactant) may be elevated in inflammation.[med-ed.virginia.edu] nonspherocytic hemolytic anemia * (n) 先天性貧血 P614 ** せんてんせいひんけつ PubMed, Scholar, Google, WikiPedia congenital anemia * (n*) 先天性溶血性貧血 *** せんてんせいようけつせいひんけつ シソーラス PubMed, Scholar[lsd-project.jp]