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1,298 Possible Causes for Acquired Spherocytosis, Genu Valgum, Some Patients May Be Clinically Asymptomatic

  • Vitamin D Deficiency

    It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] However, severe vitamin D deficiency may manifest as rickets with the below clinical features: Bony Signs - Swelling of wrists and ankles - Leg deformities (genu varum or[starship.org.nz] valgum) - Rachitic rosary in the chest wall ( enlarged costochondral joints) - Delayed tooth eruption (no incisors by aged 10 months, no molars by age 18 months) - Craniotabes[starship.org.nz]

    Missing: Acquired Spherocytosis
  • Hypophosphatemia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] In infants and children, the signs and symptoms include: Abnormal "waddling" walk due to knock-knees (genu valgum) or bowed legs (genu varum) Thick wrists Ribs of the chest[dovemed.com] A recent study describes the variability in clinical manifestations in one family, including asymptomatic adults, others with bone pain in the sixth decade of life and children[scielo.br]

  • Cooley's Anemia

    Acquired Hemolytic Anemia Some of the conditions or factors involved in acquired forms of hemolytic anemia include: Autoimmune disorders —conditions in which the body produces[labtestsonline.org] In uncomplicated cases, skeletal deformities include genu valgum, frontal bossing, malar bone prominence, depression of the nasal bridge, and maxillae hypertrophy.[symptoma.com] Untreated or poorly transfused patients show growth retardation, pallor, jaundice, poor musculature, genu valgum, leg ulcers, formation of masses due to extramedullary hematopoiesis[orpha.net]

    Missing: Some Patients May Be Clinically Asymptomatic
  • Osteomalacia

    The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] Bowing of the legs (genu varum) is typical, but knock knees (genu valgum) can also occur.[patient.info] A recent study describes the variability in clinical manifestations in one family, including asymptomatic adults, others with bone pain in the sixth decade of life and children[scielo.br]

    Missing: Acquired Spherocytosis
  • Osteoarthritis

    We here report a case of a 50-year-old male with ankle osteoarthritis and lower limb deformity, for which simultaneous deformity correction and arthrodiastasis were performed. The patient initially experienced an open fracture on the left tibia at 19 years, but it was malunited. The Japanese Society for Surgery[…][ncbi.nlm.nih.gov]

    Missing: Acquired Spherocytosis Some Patients May Be Clinically Asymptomatic
  • Hereditary Spherocytosis

    Hereditary spherocytosis (HS) is the third most common yet most frequently underrecognized, congenitally acquired hemolytic disease of the neonate.[ncbi.nlm.nih.gov] It should be emphasized, however, that decreased membrane surface area is a hallmark of spherocytes of various origins and may also be transiently observed in acquired spherocytosis[bloodjournal.org] Hereditary spherocytosis is caused by a defect of one or more erythrocyte membrane proteins, which leads to an increased rate of destruction of circulating red blood cells[ncbi.nlm.nih.gov]

    Missing: Genu Valgum Some Patients May Be Clinically Asymptomatic
  • Mucopolysaccharidosis

    valgum, waddling gait, and laxity of joints.[ncbi.nlm.nih.gov] Abstract A 16-year-old boy with widening of the large joints of the extremities and bilateral genu valgum had been extensively treated with oral vitamin D, with little clinical[ncbi.nlm.nih.gov] valgum, short stature, spinal curvature, odontoid hypoplasia, ligamentous laxity, and atlantoaxial instability MPS IV (mild) – Much slower progression of skeletal dysplasia[emedicine.medscape.com]

    Missing: Acquired Spherocytosis Some Patients May Be Clinically Asymptomatic
  • Marfan Syndrome

    Da Wikimedia Commons, l'archivio di file multimediali liberi Jump to navigation Jump to search Radiologia : Ultrasuoni sindrome di Marfan patologia autosomica dominante che colpisce il tessuto connettivo Carica un file multimediale Wikipedia Istanza di malattia, Designated intractable/rare diseases Sottoclasse di marfanoid,[…][commons.wikimedia.org]

    Missing: Acquired Spherocytosis Some Patients May Be Clinically Asymptomatic
  • Mucopolysaccharidosis 4A

    MPS-IVA commonly manifests in form of kyphosis or gibbus, scoliosis, pectus carinatum, genu valgum, gait disturbances and frequent falls, but the clinical presentation varies[symptoma.com] Skeletal deformities (platyspondyly, kyphosis, scoliosis, pectus carinatum , genu valgum , long bone deformities) become more pronounced as the child grows.[orpha.net] Clinical features include short trunk dwarfism, dysostosis multiplex, progressive spinal deformity, short neck, pectus carinatum, genu valgum, pes planus, and odontoid hypoplasia[icd10data.com]

    Missing: Acquired Spherocytosis Some Patients May Be Clinically Asymptomatic
  • Mucopolysaccharidosis 4

    They presented marked growth retardation, spinal deformity, chest deformity, genu valgum, and corneal opacities.[cags.org.ae] valgum Thoracic manifestations anterior sternal bowing, increased AP chest diameter, wide ribs Echocardiography late onset aortic regurgitation Treatment and Prognosis Life[radiopaedia.org] There is joint laxity and knock knees (genu valgum) and hip deformity (dysplasia). The intelligence is normal.[medicinenet.com]

    Missing: Acquired Spherocytosis Some Patients May Be Clinically Asymptomatic

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