Create issue ticket

25 Possible Causes for Acquired Spherocytosis, Polychromasia in Peripheral Blood Smear

  • Autoimmune Hemolytic Anemia

    D58.1 Hereditary elliptocytosis D58.2 Other hemoglobinopathies D58.8 Other specified hereditary hemolytic anemias D58.9 Hereditary hemolytic anemia, unspecified D59 Acquired[icd10data.com] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] Red blood cell agglutination, polychromasia, target cells and spherocytes were seen on a peripheral smear.[doi.org]

  • Microangiopathic Hemolytic Anemia

    D58.1 Hereditary elliptocytosis D58.2 Other hemoglobinopathies D58.8 Other specified hereditary hemolytic anemias D58.9 Hereditary hemolytic anemia, unspecified D59 Acquired[icd10data.com] The peripheral blood smear revealed polychromasia, poikilocytosis, and many schistocytes. Bone marrow biopsy disclosed metastatic carcinoma.[ncbi.nlm.nih.gov] Hemosiderinuria is seen in chronic intravascular hemolysis. 4) Examination of blood smear: Careful examination of peripheral blood smear by an experienced person provides[bioline.org.br]

  • Acquired Spherocytosis

    The test was positive in acquired spherocytosis and negative in normal controls.[moh-it.pure.elsevier.com] […] hemoglobin concentration (MCHC) and the mean corpuscular volume (MCV), and to examine the peripheral blood smear for the presence of spherocytes and polychromasia. 17 Typically[pediatrics.aappublications.org] (Panel A) Blood smear from a 73-year-old man with a myelodysplastic syndrome and acquired spherocytosis.[bloodjournal.org]

  • Congenital Dyserythropoietic Anemia

    […] dyserythropoiesis (myelodysplastic syndrome, acute erythroid leukemia), hemolytic anemias (hereditary spherocytosis) or microcytic anemias (thalassemias and iron deficiency[rarediseases.info.nih.gov] Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[ncbi.nlm.nih.gov] (B12 deficiency, folic acid deficiency or other megaloblastic anemias such as pernicious anemia or thiamine-responsive megaloblastic anemia syndrome ; see these terms), acquired[rarediseases.info.nih.gov]

  • Acquired Hemolytic Anemia

    Definition / general Congenital (hereditary spherocytosis, sickle cell) or acquired Acquired cases are usually due to deposition of immune complexes on red blood cell membranes[pathologyoutlines.com] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] , nonspherocytic congenital hemolytic anemia due to glucose-6-phosphate dehydrogenase deficiency, acquired hemolytic anemia and vitamin B12 deficiency induced megaloblastic[ncbi.nlm.nih.gov]

  • Paroxysmal Cold Hemoglobinuria

    Spherocytes hereditary spherocytosis, immune-mediated hemolytic anemia If considered hereditary – osmotic fragility test, RBC membrane protein studies If considered acquired[medcaretips.com] Tests include complete blood count (CBC) and peripheral smear.[emedicine.com] The complete blood count usually shows normocytic anemia. Reticulocytosis may be subtle in the acute phase. Peripheral blood smear may show corresponding polychromasia.[en.wikipedia.org]

  • Normocytic Normochromic Anemia

    Haemolytic Anaemias Aetiology Congenital (Intracorpuscular): Spherocytosis.[gfmer.ch] Peripheral blood smear shows: Microcytosis and hypochromasia. There is anisocytosis, poikilocytosis. There are pencil cells (elliptical RBCs).[labpedia.net] Acquired (Extracorpuscular): Chemicals: e.g. drugs, lead and snake venum. Infections: e.g. malaria and clostridium welchii. Hypersplenism.[gfmer.ch]

  • Cold Agglutinin Disease

    Corpuscular hemolytic anemias Erythrocytic membrane defects Hereditary spherocytosis Paroxysmal nocturnal hemoglobinuria ( PNH ) Description : : an acquired genetic defect[amboss.com] Reticulocytes and Spherocytes The results of the reticulocyte count are usually increased in patients with cold agglutinin disease, with polychromasia in the peripheral blood[web.archive.org] D58.1 Hereditary elliptocytosis D58.2 Other hemoglobinopathies D58.8 Other specified hereditary hemolytic anemias D58.9 Hereditary hemolytic anemia, unspecified D59 Acquired[icd10data.com]

  • Congenital Hemolytic Anemia

    Definition / general Congenital (hereditary spherocytosis, sickle cell) or acquired Acquired cases are usually due to deposition of immune complexes on red blood cell membranes[pathologyoutlines.com] Laboratory The review of the peripheral blood smear revealed no evidence of the schistocytes or fragmented red cells.[medcraveonline.com] Abnormalities include hereditary cell membrane disorders (eg, hereditary spherocytosis ), acquired cell membrane disorders (eg, paroxysmal nocturnal hemoglobinuria ), disorders[merckmanuals.com]

  • Nonimmune Hemolysis

    Classification of Hemolytic Anemias List hereditary and acquired non-immune causes of hemolytic anemia.[hematology.org] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] One good way to think about the causes of hemolytic anemia is to break them down into inherited and acquired causes.[pathologystudent.com]

Further symptoms