Acrocyanosis: Causes & Reasons

Possible Causes for Acrocyanosis

Raynaud Syndrome

Occasionally, an alternate explanation is revealed such as acrocyanosis. [ncbi.nlm.nih.gov]

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

Of note, RP may occur concomitantly with acrocyanosis. [intechopen.com]

Cryoglobulinemia

A 71-year-old man comes to our observation because of the onset of persistence of paresthesia and painful acrocyanosis in the fingers and toes. [ncbi.nlm.nih.gov]

Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration. [dermpedia.org]

POEMS Syndrome

Report of Case A 60-year-old woman presented with a progressive sensorimotor polyneuropathy, weight loss, and acrocyanosis of the distal extremities and nose. [mayoclinicproceedings.org]

[…] by diabetes mellitus or hypothyroidism as these are common in the general population skin changes (hyperpigmentation, hypertrichosis, glomeruloid hemangiomata, plethora, acrocyanosis [radiopaedia.org]

Other possible clinical manifestations include: skin changes such as hyperpigmentation, skin thickening, and excessive sweating; acrocyanosis, that is, the bluish color of [gsdinternational.com]

Chilblain

Lesions were papular with signs of peripheral vasoconstriction causing acrocyanosis, and uncomfortable due to pain and/or pruritis in most. [ncbi.nlm.nih.gov]

Acrocyanosis Acrocyanosis is a symmetric painless, discoloration of different shades of blue in the distal parts of the body (fingers and toes and, in some cases, the entire [lucianoschiazza.it]

Chilblains are more likely to develop in those with poor peripheral circulation, noted by blue-red mottled skin on the limbs ( acrocyanosis ). [dermnetnz.org]

Raynaud Disease

Acrocyanosis affects both men and women, and the age at onset is usually between 20 and 45 years. [hyperhidrosis-usa.com]

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

Other vasospastic disorders that should be included in the differential but are usually easily distinguishable by physical examination are acrocyanosis and livedo reticularis [health.am]

Idiopathic Cryoglobulinemia

Features of Type I cryoglobulinaemia Features of Type II and III cryoglobulinaemia Acrocyanosis (blueness of the hands and feet from the cold Blue toe syndrome Retinal haemorrhage [dermnetnz.org]

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [healthnutvitamin.com]

Autoimmune Hemolytic Anemia

Affected individuals which test positive for cold agglutinins, develop acrocyanosis in cold weather. [symptoma.com]

[…] antibodies type II hypersensitivity Epidemiology peak incidence in 50s-80s Presentation Symptoms warm agglutinin disease chronic hemolytic anemia cold agglutinin disease acrocyanosis [step1.medbullets.com]

CAIHA patients may experience bluish, cold hands and feet (acrocyanosis) and abdominal pain when eating cold food. [symptoma.com]

Fucosidosis

Other cutaneous features in this patient included distal transverse purple nail bands, acrocyanosis and a naevus anaemicus. [ncbi.nlm.nih.gov]

[…] pyramidal sign 0007256 Abnormality of the dentition Abnormal dentition Abnormal teeth Dental abnormalities Dental abnormality [ more ] 0000164 Abnormality of the nail 0001597 Acrocyanosis [rarediseases.info.nih.gov]

Cryoimmunoglobulinemic Syndrome

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Anorexia Nervosa

[…] affected • Constipation • Amenorrhea • Vital signs: bradycardia, hypotension, and mild hypothermia • Lanugo hair in back, forearm and cheeks • Salivary gland enlargement • Acrocyanosis [slideshare.net]

Hg decrease in systolic BP or a 10 mm Hg decrease in diastolic BP within 3 minutes of standing from a supine position.12 Other notable findings include hypercarotenemia, acrocyanosis [journals.lww.com]

Examination can be normal but findings could include bradycardia, hypotension, peripheral oedema, gaunt face, lanugo hair, scanty pubic hair, and acrocyanosis (hands or feet [patient.info]

Thromboangiitis Obliterans

The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance [ncbi.nlm.nih.gov]

[…] obliterans [Buerger's disease] I73.8 Other specified peripheral vascular diseases I73.81 Erythromelalgia I73.89 Other specified peripheral vascular diseases Inclusion term(s): Acrocyanosis [icd10coded.com]

Sclerodactyly

Several conditions may present with findings similar to those of PSS.[ 1 ] Acrocyanosis may be seen with pulmonary hypertension, anorexia nervosa and frost-bite but without [ncbi.nlm.nih.gov]

Limited Cutaneous Systemic Scleroderma

Extra-oral examination underlined taut, thickened and rigid skin, pallid-red irregular maculae all over the face, telangiectasias and acrocyanosis. [ncbi.nlm.nih.gov]

Skin manifestations include hyperpigmentation, a recent outcropping of hemangiomas, hypertrichosis, dependent rubor and acrocyanosis, white nails, sclerodermoid changes, flushing [cancernetwork.com]

Dyskeratosis Congenita

Hyperhidrosis of palms and soles, blister formation, acrocyanosis, hair loss (scalp), and early tooth loss also occur. [visualdx.com]

Disseminated Intravascular Coagulation

Consider heparin (300-500 U/hr) for DIC manifested by thrombosis or acrocyanosis in the absence of active bleeding. 5 Anti-fibrinolytics (tranexamic acid and ε-amioncaproic [emdocs.net]

Hyperviscosity Syndrome

Type I cryoglobulinemia is frequently asymptomatic per se but patients may develop acrocyanosis, retinal hemorrhage, Raynaud's phenomenon, and arterial thrombosis. [orpha.net]

Eating Disorder

These manifestations include xerosis, lanugo-like body hair, telogen effluvium, carotenoderma, acne, hyperpigmentation, seborrheic dermatitis, acrocyanosis, perniosis, petechiae [ncbi.nlm.nih.gov]

Methemoglobinemia

2017) : No change 2019 (effective 10/1/2018) : No change Cyanosis R23.0 ICD-10-CM Diagnosis Code R23.0 Cyanosis 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes acrocyanosis [icd10data.com]

The initial physical exam was significant for acrocyanosis. [mhnpjournal.biomedcentral.com]

Diffuse Cutaneous Systemic Scleroderma

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [livingnaturallyonline.com]

Pulmonary Hypertension

Signs of right heart failure, ie, extended neck veins, edema, ascites, and acrocyanosis, occur late in the course of the disease and may signal a life-threatening situation [doi.org]

Iron Deficiency Anemia

Abstract Our aim was to evaluate the cut-off value and efficiency of using reticulocyte hemoglobin content as a marker to diagnose iron deficiency anemia in Chinese adults. 140 adults who needed bone marrow aspiration for diagnosis at the hematology department of the Peking Union Medical College Hospital were[…] [ncbi.nlm.nih.gov]

Heart Failure

It is widely known that β-blockers exert beneficial effects on non-ischemic and ischemic systolic heart failure (sHF) in nonstructural hearts. However, whether β-blockers exert similar effects on sHF associated with congenital heart disease (CHD), particularly in an anatomical right ventricle, remains under[…] [ncbi.nlm.nih.gov]

Congestive Heart Failure

Severe congestive heart failure (CHF) patients are prone to hyponatremia. Peritoneal dialysis (PD) is increasingly used for long-term management of refractory CHF patients. The glucose polymer icodextrin was proposed to be a good option for fluid removal in such patients. A small, although statistically significant[…] [ncbi.nlm.nih.gov]

Hypovolemia

By, August 6th 2013. Last reviewed 20th March 2018. What is hypovolemia? The medical definition of hypovolemia is a decrease of the volume of circulating blood [Greek hypo = less; vol = volume; emia refers to blood] 1. Symptoms and Signs Symptoms and signs of hypovolemia (pale, cool and moist skin, increased heart[…] [ehealthstar.com]

Chronic Right-Sided Congestive Heart Failure

Fonti utilizzate nella revisione corrente (2015 November 6 Updated). What Is Heart Failure? National Heart, Lung, and Blood Institute [On-line information]. Available online at http://www.nhlbi.nih.gov/health/health-topics/topics/hf. Accessed March 2016. Dumitru, I. and Baker, M. (2016 Jan 11 Updated).Heart Failure.Medscape[…] [labtestsonline.it]

Carbon Monoxide Poisoning

Carbon monoxide (CO) poisoning causes acute symptoms such as headache, nausea, weakness, angina, dyspnea, loss of consciousness, seizures, and coma. Neuropsychiatric symptoms may develop weeks later. Diagnosis is by carboxyhemoglobin levels and arterial blood gases (ABGs), including measured oxygen saturation.[…] [merckmanuals.com]

Bacterial Meningitis

Mondini dysplasia is rare, but has an important association with recurrent bacterial meningitis. We herein describe the case of a 3-year-old girl with unilateral sensorineural hearing loss who presented with three independent episodes of bacterial meningitis within 8 months. Temporal bone computed tomography indicated[…] [ncbi.nlm.nih.gov]

Hypovolemic Shock

[…] close Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Log out Cancel Updated: Oct 13, 2016 Author: Paul Kolecki, MD, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP more... Overview Background[…] [emedicine.medscape.com]

Neonatal Meningitis

Early neonatal meningitis with non-fermenting Gram negative bacilli (NFGNB) is rare, and whenever it occurrs, inanimate environment is usually implicated as the source. The authors report a case of neonatal meningitis and sepsis with Chryseobacterium indologenes, a rare non fermenting Gram negative bacterium with[…] [ncbi.nlm.nih.gov]

Cervical Rib Syndrome

Abstract A series of 38 patients with thoracic outlet syndrome caused by a cervical rib is reviewed after a postoperative follow-up period of 3 to 24 years. The outcome of the operation (anterior scalenotomy and partial to subtotal removal of the cervical rib) is not considered wholly satisfactory; three causes[…] [ncbi.nlm.nih.gov]