Acrocyanosis: Causes & Reasons

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Possible Causes for Acrocyanosis

Raynaud Syndrome

Occasionally, an alternate explanation is revealed such as acrocyanosis. [ncbi.nlm.nih.gov]

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

Of note, RP may occur concomitantly with acrocyanosis. [intechopen.com]

Cryoglobulinemia

A 71-year-old man comes to our observation because of the onset of persistence of paresthesia and painful acrocyanosis in the fingers and toes. [ncbi.nlm.nih.gov]

Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration. [dermpedia.org]

Chilblain

Lesions were papular with signs of peripheral vasoconstriction causing acrocyanosis, and uncomfortable due to pain and/or pruritis in most. [ncbi.nlm.nih.gov]

Acrocyanosis Acrocyanosis is a symmetric painless, discoloration of different shades of blue in the distal parts of the body (fingers and toes and, in some cases, the entire [lucianoschiazza.it]

Chilblains are more likely to develop in those with poor peripheral circulation, noted by blue-red mottled skin on the limbs ( acrocyanosis ). [dermnetnz.org]

Raynaud Disease

Acrocyanosis affects both men and women, and the age at onset is usually between 20 and 45 years. [hyperhidrosis-usa.com]

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

See also acrocyanosis. This article was most recently revised and updated by Amy Tikkanen, Corrections Manager. [britannica.com]

Idiopathic Cryoglobulinemia

Features of Type I cryoglobulinaemia Features of Type II and III cryoglobulinaemia Acrocyanosis (blueness of the hands and feet from the cold Blue toe syndrome Retinal haemorrhage [dermnetnz.org]

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [grainbininc.com]

POEMS Syndrome

The most common findings are hyperpigmentation, hypertrichosis, acrocyanosis, plethora and hemangiomas [ 5 ]. [karger.com]

[…] adrenal, thyroid, pituitary, gonadal, parathyroid, pancreatic); hypogonadism most common Skin changes (hyperpigmentation, hypertrichosis, glomeruloid angiomata, plethora, acrocyanosis [pathologyoutlines.com]

Cutaneous alterations are present in 68% of patients with diffuse cutaneous hyperpigmentation, plethora and acrocyanosis. [karger.com]

Autoimmune Hemolytic Anemia

[…] antibodies type II hypersensitivity Epidemiology peak incidence in 50s-80s Presentation Symptoms warm agglutinin disease chronic hemolytic anemia cold agglutinin disease acrocyanosis [medbullets.com]

Affected individuals which test positive for cold agglutinins, develop acrocyanosis in cold weather. [symptoma.com]

CAIHA patients may experience bluish, cold hands and feet (acrocyanosis) and abdominal pain when eating cold food. [symptoma.com]

Fucosidosis

Other cutaneous features in this patient included distal transverse purple nail bands, acrocyanosis and a naevus anaemicus. [ncbi.nlm.nih.gov]

[…] pyramidal sign 0007256 Abnormality of the dentition Abnormal dentition Abnormal teeth Dental abnormalities Dental abnormality [ more ] 0000164 Abnormality of the nail 0001597 Acrocyanosis [rarediseases.info.nih.gov]

Anorexia Nervosa

[…] affected • Constipation • Amenorrhea • Vital signs: bradycardia, hypotension, and mild hypothermia • Lanugo hair in back, forearm and cheeks • Salivary gland enlargement • Acrocyanosis [slideshare.net]

Hg decrease in systolic BP or a 10 mm Hg decrease in diastolic BP within 3 minutes of standing from a supine position.12 Other notable findings include hypercarotenemia, acrocyanosis [journals.lww.com]

Examination can be normal but findings could include bradycardia, hypotension, peripheral oedema, gaunt face, lanugo hair, scanty pubic hair, and acrocyanosis (hands or feet [patient.info]

Thromboangiitis Obliterans

The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance [ncbi.nlm.nih.gov]

[…] obliterans [Buerger's disease] I73.8 Other specified peripheral vascular diseases I73.81 Erythromelalgia I73.89 Other specified peripheral vascular diseases Inclusion term(s): Acrocyanosis [icd10coded.com]

Cryoimmunoglobulinemic Syndrome

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Sclerodactyly

Several conditions may present with findings similar to those of PSS.[ 1 ] Acrocyanosis may be seen with pulmonary hypertension, anorexia nervosa and frost-bite but without [ncbi.nlm.nih.gov]

Limited Cutaneous Systemic Scleroderma

Extra-oral examination underlined taut, thickened and rigid skin, pallid-red irregular maculae all over the face, telangiectasias and acrocyanosis. [ncbi.nlm.nih.gov]

Skin manifestations include hyperpigmentation, a recent outcropping of hemangiomas, hypertrichosis, dependent rubor and acrocyanosis, white nails, sclerodermoid changes, flushing [cancernetwork.com]

Dyskeratosis Congenita

Hyperhidrosis of palms and soles, blister formation, acrocyanosis, hair loss (scalp), and early tooth loss also occur. [visualdx.com]

Eating Disorder

These manifestations include xerosis, lanugo-like body hair, telogen effluvium, carotenoderma, acne, hyperpigmentation, seborrheic dermatitis, acrocyanosis, perniosis, petechiae [ncbi.nlm.nih.gov]

Disseminated Intravascular Coagulation

Consider heparin (300-500 U/hr) for DIC manifested by thrombosis or acrocyanosis in the absence of active bleeding. 5 Anti-fibrinolytics (tranexamic acid and ε-amioncaproic [emdocs.net]

Hyperviscosity Syndrome

Type I cryoglobulinemia is frequently asymptomatic per se but patients may develop acrocyanosis, retinal hemorrhage, Raynaud's phenomenon, and arterial thrombosis. [orpha.net]

Diffuse Cutaneous Systemic Scleroderma

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [livingnaturallyonline.com]

Methemoglobinemia

2017) : No change 2019 (effective 10/1/2018) : No change Cyanosis R23.0 ICD-10-CM Diagnosis Code R23.0 Cyanosis 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes acrocyanosis [icd10data.com]

Pulmonary Hypertension

Signs of right heart failure, ie, extended neck veins, edema, ascites, and acrocyanosis, occur late in the course of the disease and may signal a life-threatening situation [doi.org]

Iron Deficiency Anemia

Abstract Ankaferd Blood Stopper (ABS) comprises a mixture of plants and stops bleeding via forming a protein network by erythroid aggregation. Bleeding causes reduction of iron levels in body. It has been indicated that ABS contains significant amount of iron. Thus, we investigated the biological activity of[…] [ncbi.nlm.nih.gov]

Heart Failure

Heart Fail Clin. 2018 Oct;14(4):525-535. doi: 10.1016/j.hfc.2018.06.002. Epub 2018 Aug 18. Author information 1 Department of Medicine, Section of Cardiology, Baylor College of Medicine, 6620 Main Street, 12th Floor, Suite 1225, Houston, TX 77030, USA. 2 Department of Medicine, Section of Cardiology, Baylor College of Medicine[…] [ncbi.nlm.nih.gov]

Congestive Heart Failure

Congestive heart failure occurs when the heart can no longer meet the metabolic demands of the body at normal physiologic venous pressures. Typically, the heart can respond to increased demands by means of 1 of the following: Increasing the heart rate, which is controlled by neural and humoral input Increasing[…] [emedicine.com]

Hypovolemia

Intact cerebral blood flow (CBF) is essential for cerebral metabolism and function, whereas hypoperfusion in relation to hypovolemia and hypocapnia can lead to severe cerebral damage. This study was designed to assess internal carotid artery blood flow (ICA-BF) during simulated hypovolemia and noninvasive positive[…] [ncbi.nlm.nih.gov]

Chronic Right-Sided Congestive Heart Failure

Home | CCC | Right Ventricular Failure by, last update March 24, 2019 Reviewed and revised 26 June 2014 OVERVIEW mortality as high as LV failure RV is better suited to volume overload than left due to compliance and thin wall but when PVR increases for whatever reason -> RV dilates when the dilation maximised ->[…] [lifeinthefastlane.com]

Carbon Monoxide Poisoning

Carbon monoxide poisoning is a potentially fatal condition caused by inhalation of carbon monoxide, a toxic, colorless, odorless and tasteless gas. The symptoms are acute and develop rapidly. Unborn fetuses, neonates and young children are more susceptible to harmful effects of carbon monoxide. These include:[…] [symptoma.com]

Bacterial Meningitis

Mondini dysplasia is rare, but has an important association with recurrent bacterial meningitis. We herein describe the case of a 3-year-old girl with unilateral sensorineural hearing loss who presented with three independent episodes of bacterial meningitis within 8 months. Temporal bone computed tomography indicated[…] [ncbi.nlm.nih.gov]

Hypovolemic Shock

The authors describe a new computed tomography finding associated with significant thoracoabdominal trauma: thyroidal and perithyroidal edema and fluid without evidence for direct thyroid injury. It does not seem to be related to direct or indirect thyroid injury but is rather a secondary finding related to the[…] [ncbi.nlm.nih.gov]

Neonatal Meningitis

Early neonatal meningitis with non-fermenting Gram negative bacilli (NFGNB) is rare, and whenever it occurrs, inanimate environment is usually implicated as the source. The authors report a case of neonatal meningitis and sepsis with Chryseobacterium indologenes, a rare non fermenting Gram negative bacterium with[…] [ncbi.nlm.nih.gov]

Cervical Rib Syndrome

Abstract A series of 38 patients with thoracic outlet syndrome caused by a cervical rib is reviewed after a postoperative follow-up period of 3 to 24 years. The outcome of the operation (anterior scalenotomy and partial to subtotal removal of the cervical rib) is not considered wholly satisfactory; three causes[…] [ncbi.nlm.nih.gov]