Acrocyanosis: Causes & Reasons

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Possible Causes for Acrocyanosis

Raynaud Syndrome

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

Occasionally, an alternate explanation is revealed such as acrocyanosis. [ncbi.nlm.nih.gov]

Of note, RP may occur concomitantly with acrocyanosis. [intechopen.com]

Chilblain

Lesions were papular with signs of peripheral vasoconstriction causing acrocyanosis, and uncomfortable due to pain and/or pruritis in most. [ncbi.nlm.nih.gov]

Acrocyanosis Acrocyanosis is a symmetric painless, discoloration of different shades of blue in the distal parts of the body (fingers and toes and, in some cases, the entire [lucianoschiazza.it]

Chilblains are more likely to develop in those with poor peripheral circulation, noted by blue-red mottled skin on the limbs ( acrocyanosis ). [dermnetnz.org]

Raynaud Disease

Acrocyanosis affects both men and women, and the age at onset is usually between 20 and 45 years. [hyperhidrosis-usa.com]

/or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com]

See also acrocyanosis. This article was most recently revised and updated by Amy Tikkanen, Corrections Manager. [britannica.com]

Idiopathic Cryoglobulinemia

Features of Type I cryoglobulinaemia Features of Type II and III cryoglobulinaemia Acrocyanosis (blueness of the hands and feet from the cold Blue toe syndrome Retinal haemorrhage [dermnetnz.org]

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [grainbininc.com]

Fucosidosis

Other cutaneous features in this patient included distal transverse purple nail bands, acrocyanosis and a naevus anaemicus. [ncbi.nlm.nih.gov]

[…] pyramidal sign 0007256 Abnormality of the dentition Abnormal dentition Abnormal teeth Dental abnormalities Dental abnormality [ more ] 0000164 Abnormality of the nail 0001597 Acrocyanosis [rarediseases.info.nih.gov]

Thromboangiitis Obliterans

The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance [ncbi.nlm.nih.gov]

[…] obliterans [Buerger's disease] I73.8 Other specified peripheral vascular diseases I73.81 Erythromelalgia I73.89 Other specified peripheral vascular diseases Inclusion term(s): Acrocyanosis [icd10coded.com]

Cryoimmunoglobulinemic Syndrome

Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org]

Sclerodactyly

Several conditions may present with findings similar to those of PSS.[ 1 ] Acrocyanosis may be seen with pulmonary hypertension, anorexia nervosa and frost-bite but without [ncbi.nlm.nih.gov]

Limited Cutaneous Systemic Scleroderma

Extra-oral examination underlined taut, thickened and rigid skin, pallid-red irregular maculae all over the face, telangiectasias and acrocyanosis. [ncbi.nlm.nih.gov]

Skin manifestations include hyperpigmentation, a recent outcropping of hemangiomas, hypertrichosis, dependent rubor and acrocyanosis, white nails, sclerodermoid changes, flushing [cancernetwork.com]

Hyperviscosity Syndrome

Type I cryoglobulinemia is frequently asymptomatic per se but patients may develop acrocyanosis, retinal hemorrhage, Raynaud's phenomenon, and arterial thrombosis. [orpha.net]

Disseminated Intravascular Coagulation

Consider heparin (300-500 U/hr) for DIC manifested by thrombosis or acrocyanosis in the absence of active bleeding. 5 Anti-fibrinolytics (tranexamic acid and ε-amioncaproic [emdocs.net]

Methemoglobinemia

2017) : No change 2019 (effective 10/1/2018) : No change Cyanosis R23.0 ICD-10-CM Diagnosis Code R23.0 Cyanosis 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes acrocyanosis [icd10data.com]

Diffuse Cutaneous Systemic Scleroderma

Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [livingnaturallyonline.com]

Iron Deficiency Anemia

Abstract Ankaferd Blood Stopper (ABS) comprises a mixture of plants and stops bleeding via forming a protein network by erythroid aggregation. Bleeding causes reduction of iron levels in body. It has been indicated that ABS contains significant amount of iron. Thus, we investigated the biological activity of[…] [ncbi.nlm.nih.gov]

Heart Failure

Heart Fail Clin. 2018 Oct;14(4):525-535. doi: 10.1016/j.hfc.2018.06.002. Epub 2018 Aug 18. Author information 1 Department of Medicine, Section of Cardiology, Baylor College of Medicine, 6620 Main Street, 12th Floor, Suite 1225, Houston, TX 77030, USA. 2 Department of Medicine, Section of Cardiology, Baylor College of Medicine[…] [ncbi.nlm.nih.gov]

Congestive Heart Failure

Congestive heart failure occurs when the heart can no longer meet the metabolic demands of the body at normal physiologic venous pressures. Typically, the heart can respond to increased demands by means of 1 of the following: Increasing the heart rate, which is controlled by neural and humoral input Increasing[…] [emedicine.com]

Hypovolemia

Intact cerebral blood flow (CBF) is essential for cerebral metabolism and function, whereas hypoperfusion in relation to hypovolemia and hypocapnia can lead to severe cerebral damage. This study was designed to assess internal carotid artery blood flow (ICA-BF) during simulated hypovolemia and noninvasive positive[…] [ncbi.nlm.nih.gov]

Chronic Right-Sided Congestive Heart Failure

Home | CCC | Right Ventricular Failure by, last update March 24, 2019 Reviewed and revised 26 June 2014 OVERVIEW mortality as high as LV failure RV is better suited to volume overload than left due to compliance and thin wall but when PVR increases for whatever reason -> RV dilates when the dilation maximised ->[…] [lifeinthefastlane.com]

Postural Orthostatic Tachycardia Syndrome

[…] postural orthostatic tachycardia syndrome can include a murmur or click of mitral valve prolapse (although significant mitral regurgitation is unusual) and prominent dependent acrocyanosis [medlink.com]

Heyer, 2013 ] Nausea Abdominal discomfort (ex, Chronic recurrent abdominal pain ) Inappropriate sweating Exercise intolerance Frank Syncope (~30% of patients) Dependent acrocyanosis [pedemmorsels.com]

Acrocyanosis Presentation in Postural Orthostatic Tachycardia Syndrome. International Journal Of Clinical Pediatrics, 7(1-2), 13-16. [me-pedia.org]

Cervical Rib Syndrome

Abstract A series of 38 patients with thoracic outlet syndrome caused by a cervical rib is reviewed after a postoperative follow-up period of 3 to 24 years. The outcome of the operation (anterior scalenotomy and partial to subtotal removal of the cervical rib) is not considered wholly satisfactory; three causes[…] [ncbi.nlm.nih.gov]

Thoracic Outlet Syndrome

Thoracic outlet syndrome (TOS) is a condition in which there is compression of the nerves, arteries, or veins in the passageway from the lower neck to the armpit. There are three main types: neurogenic, venous, and arterial. The neurogenic type is the most common and presents with pain, weakness, and occasionally[…] [en.wikipedia.org]

Cold Agglutinin Disease

After nine months of ATT, his haemoglobin improved, acrocyanosis resolved completely and cold agglutinin titer decreased in level. [ncbi.nlm.nih.gov]

A 60-year-old male who had been treated for polymyalgia rheumatica (PMR) with Raynaud's phenomenon was admitted to our hospital with acrocyanosis and rapid progressive anemia [ncbi.nlm.nih.gov]

Agglutination results in impaired perfusion, resulting in symptomatic Raynaud's phenomenon and acrocyanosis. [ncbi.nlm.nih.gov]

Acrodermatitis Enteropathica

Background Acrodermatitis enteropathica is a rare inherited form of zinc deficiency, characterized by periorificial and acral dermatitis, alopecia, and diarrhea. Pathophysiology Zinc is an essential trace nutrient required for the proper function of more than 100 enzymes and plays a crucial role in nucleic acid[…] [emedicine.com]

Acrocyanosis

Acrocyanosis is often secondary to a variety of underlying causes. [ncbi.nlm.nih.gov]

The precise mechanism of acrocyanosis is not known. [en.wikipedia.org]

The authors present three men with both acrocyanosis and Asperger's syndrome. [ncbi.nlm.nih.gov]

Idiopathic Recurrent and Disabling Cutaneous Herpes

Raynaud phenomenon, livedo reticularis, and acrocyanosis are common in type I cryoglobulinemia. [emedicine.medscape.com]

The most common cutaneous manifestations associated with cold agglutinins are acrocyanosis and Raynaud phenomenon. [emedicine.medscape.com]

Plasmapheresis should be reserved for patients with ongoing severe hemolysis, severe acrocyanosis, or anti-Pr antibodies and polyneuropathy, and as preoperative management [emedicine.medscape.com]

Hemophagocytic Lymphohistiocytosis

An 8-month-old girl had classic features of hemophagocytic lymphohistiocytosis (HLH). A presumptive diagnosis of familial hemophagocytic lymphohistiocytosis was made on the basis of her age and the presence of parental consanguinity. In view of abnormal neurologic findings at presentation, a magnetic resonance[…] [ncbi.nlm.nih.gov]

Cryoglobulinemia

A 71-year-old man comes to our observation because of the onset of persistence of paresthesia and painful acrocyanosis in the fingers and toes. [ncbi.nlm.nih.gov]

Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration. [dermpedia.org]

Frostbite

Address life-threatening conditions first. Fluid resuscitation, especially in persons with frostbite occurring at altitude, enhances blood flow and tissue perfusion. Rapidly rewarm the affected body part, avoiding further trauma. An appropriate warming technique is the use of a whirlpool bath or tub of water at[…] [emedicine.com]

Cockayne Syndrome

Cockayne syndrome (CS), also called Neill-Dingwall syndrome, is a rare and fatal autosomal recessive neurodegenerative disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), eye disorders and premature aging. Failure to thrive and[…] [en.wikipedia.org]

Purpura Fulminans

[Article in English, German] Author information 1 Department of Dermatology, Clinic Kassel, Mönchebergstrasse 41-43, Kassel, Germany. jakob@klinikum-kassel.de Abstract Purpura fulminans features the sudden onset of large rapidly-spreading areas of hemorrhagic skin necrosis. This is followed by a disseminated[…] [ncbi.nlm.nih.gov]