Possible Causes for acrocyanosis Raynaud Syndrome Occasionally, an alternate explanation is revealed such as acrocyanosis. [ncbi.nlm.nih.gov] […] or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com] Of note, RP may occur concomitantly with acrocyanosis. [intechopen.com] Raynaud Disease Acrocyanosis affects both men and women, and the age at onset is usually between 20 and 45 years. [hyperhidrosis-usa.com] Other vasospastic disorders that should be included in the differential but are usually easily distinguishable by physical examination are acrocyanosis and livedo reticularis [health.am] […] or a unilateral acrocyanosis. [ped-rheum.biomedcentral.com] Iron Deficiency Anemia INTRODUCTION Iron deficiency anemia (IDA) is a common complication in routine clinical practice that frequently originates in the gastrointestinal (GI) tract[ 1 - 3 ]. Patients with IDA are therefore often referred to gastroenterologists for further examination and/or treatment. IDA associated with GI disorders can[…] [dx.doi.org] Heart Failure Several new devices for the treatment of heart failure (HF) patients have been introduced and are increasingly used in clinical practice or are under clinical evaluation in either observational and/or randomized clinical trials. These devices include cardiac contractility modulation, spinal cord stimulation, carotid sinus[…] [ncbi.nlm.nih.gov] Congestive Heart Failure Congestive heart failure occurs when the heart can no longer meet the metabolic demands of the body at normal physiologic venous pressures. Typically, the heart can respond to increased demands by means of 1 of the following: Increasing the heart rate, which is controlled by neural and humoral input Increasing[…] [emedicine.medscape.com] Hypovolemia Intact cerebral blood flow (CBF) is essential for cerebral metabolism and function, whereas hypoperfusion in relation to hypovolemia and hypocapnia can lead to severe cerebral damage. This study was designed to assess internal carotid artery blood flow (ICA-BF) during simulated hypovolemia and noninvasive positive[…] [ncbi.nlm.nih.gov] Disseminated Intravascular Coagulation Consider heparin (300-500 U/hr) for DIC manifested by thrombosis or acrocyanosis in the absence of active bleeding. 5 Anti-fibrinolytics (tranexamic acid and ε-amioncaproic [emdocs.net] Chronic Right-Sided Congestive Heart Failure Home CCC Right Ventricular Failure by, last update March 24, 2019 Reviewed and revised 26 June 2014 OVERVIEW mortality as high as LV failure RV is better suited to volume overload than left due to compliance and thin wall but when PVR increases for whatever reason - RV dilates when the dilation maximised - reversal[…] [lifeinthefastlane.com] Diffuse Cutaneous Systemic Scleroderma Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [livingnaturallyonline.com] Sclerodactyly Several conditions may present with findings similar to those of PSS.[ 1 ] Acrocyanosis may be seen with pulmonary hypertension, anorexia nervosa and frost-bite but without [ncbi.nlm.nih.gov] Limited Cutaneous Systemic Scleroderma Extra-oral examination underlined taut, thickened and rigid skin, pallid-red irregular maculae all over the face, telangiectasias and acrocyanosis. [ncbi.nlm.nih.gov] Skin manifestations include hyperpigmentation, a recent outcropping of hemangiomas, hypertrichosis, dependent rubor and acrocyanosis, white nails, sclerodermoid changes, flushing [cancernetwork.com] Chilblain Lesions were papular with signs of peripheral vasoconstriction causing acrocyanosis, and uncomfortable due to pain and/or pruritis in most. [ncbi.nlm.nih.gov] Acrocyanosis Acrocyanosis is a symmetric painless, discoloration of different shades of blue in the distal parts of the body (fingers and toes and, in some cases, the entire [lucianoschiazza.it] Six out of the seven patients referred typical Raynaud’s phenomenon and one had acrocyanosis. [doi.org] Thromboangiitis Obliterans The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance [ncbi.nlm.nih.gov] […] obliterans [Buerger's disease] I73.8 Other specified peripheral vascular diseases I73.81 Erythromelalgia I73.89 Other specified peripheral vascular diseases Inclusion term(s): Acrocyanosis [icd10coded.com] Cryoimmunoglobulinemic Syndrome Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org] Cervical Rib Syndrome Abstract A series of 38 patients with thoracic outlet syndrome caused by a cervical rib is reviewed after a postoperative follow-up period of 3 to 24 years. The outcome of the operation (anterior scalenotomy and partial to subtotal removal of the cervical rib) is not considered wholly satisfactory; three causes[…] [ncbi.nlm.nih.gov] Thoracic Outlet Syndrome Thoracic outlet syndrome (TOS) refers to a group of complex symptoms in the upper extremity caused by compression of the brachial plexus, subclavian artery and vein. Different surgical approaches were described for the management of TOS. There is, however, no "gold standard" procedure for this complicated and[…] [ncbi.nlm.nih.gov] Idiopathic Cryoglobulinemia Features of Type I cryoglobulinaemia Features of Type II and III cryoglobulinaemia Acrocyanosis (blueness of the hands and feet from the cold Blue toe syndrome Retinal haemorrhage [dermnetnz.org] Interruption of blood flow to other tissues in type I disease can cause cutaneous manifestations of purpura, blue discoloration of the arms or legs (acrocyanosis), necrosis [en.wikipedia.org] Use cautiously with Raynaud's disease, chilblains, acrocyanosis, erythrocyanosis, or impaired temperature sensitivity, such as neuropathy. [healthnutvitamin.com] Cold Agglutinin Disease After nine months of ATT, his haemoglobin improved, acrocyanosis resolved completely and cold agglutinin titer decreased in level. [ncbi.nlm.nih.gov] A 60-year-old male who had been treated for polymyalgia rheumatica (PMR) with Raynaud's phenomenon was admitted to our hospital with acrocyanosis and rapid progressive anemia [ncbi.nlm.nih.gov] Agglutination results in impaired perfusion, resulting in symptomatic Raynaud's phenomenon and acrocyanosis. [ncbi.nlm.nih.gov] Brandt Syndrome From Wikidata Jump to navigation Jump to search Human disease Acrodermatitis enteropathica, zinc deficiency type Acrodermatitis enteropathica zinc deficiency type Inherited zinc deficiency Danbolt-Cross syndrome ACRODERMATITIS ENTEROPATHICA, ZINC-DEFICIENCY TYPE; AEZ Brandt syndrome AE ACRODERMATITIS[…] [wikidata.org] Fucosidosis Other cutaneous features in this patient included distal transverse purple nail bands, acrocyanosis and a naevus anaemicus. [ncbi.nlm.nih.gov] […] pyramidal sign 0007256 Abnormality of the dentition Abnormal dentition Abnormal teeth Dental abnormalities Dental abnormality [ more ] 0000164 Abnormality of the nail 0001597 Acrocyanosis [rarediseases.info.nih.gov] Postural Orthostatic Tachycardia Syndrome […] postural orthostatic tachycardia syndrome can include a murmur or click of mitral valve prolapse (although significant mitral regurgitation is unusual) and prominent dependent acrocyanosis [medlink.com] Heyer, 2013 ] Nausea Abdominal discomfort (ex, Chronic recurrent abdominal pain ) Inappropriate sweating Exercise intolerance Frank Syncope ( 30% of patients) Dependent acrocyanosis [pedemmorsels.com] Acrocyanosis Presentation in Postural Orthostatic Tachycardia Syndrome. International Journal Of Clinical Pediatrics, 7(1-2), 13-16. [me-pedia.org] Acrocyanosis The precise mechanism of acrocyanosis is not known. [en.wikipedia.org] Acrocyanosis is often secondary to a variety of underlying causes. [ncbi.nlm.nih.gov] The authors present three men with both acrocyanosis and Asperger's syndrome. [ncbi.nlm.nih.gov] Methemoglobinemia 2017) : No change 2019 (effective 10/1/2018) : No change Cyanosis R23.0 ICD-10-CM Diagnosis Code R23.0 Cyanosis 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes acrocyanosis [icd10data.com] Familial Hemophagocytic Lymphohistiocytosis Familial hemophagocytic lymphohistiocytosis is a rare autosomal recessive disorder of immune dysregulation associated with uncontrolled activation of cytotoxic T cells and macrophages. Herein, we report a case of a 14-month-old Chinese boy who presented with fever, abdominal distension and thrombopenia, and died[…] [ncbi.nlm.nih.gov] Frostbite A 25-year-old woman complained of numbness of the extremities, following muscle rigidity and tenderness. The presence of anti-voltage-gated potassium channel antibody led to the diagnosis of Isaacs' syndrome. Twenty-seven months after the first symptom, she developed a pricking pain sensation in the lateral left[…] [ncbi.nlm.nih.gov] Cockayne Syndrome Cerebro-oculo-facio-skeletal (COFS) syndrome is a rapidly progressive neurological disorder leading to brain atrophy with calcification, cataracts, microcornea, optic atrophy, progressive joint contractures, and growth failure. Cockayne syndrome (CS) is a recessively inherited neurodegenerative disorder characterized[…] [ncbi.nlm.nih.gov] Hyperviscosity Syndrome Type I cryoglobulinemia is frequently asymptomatic per se but patients may develop acrocyanosis, retinal hemorrhage, Raynaud's phenomenon, and arterial thrombosis. [orpha.net] Purpura Fulminans Dermal vascular skin necrosis is associated with a complex group of clinical disorders. Many of these disorders are associated with an underlying abnormality of the PC anticoagulant system or DIC, or both. The clinical appearance and histopathologic features of dermal vascular skin necrosis are similar regardless of[…] [ncbi.nlm.nih.gov] Homocystinuria Homocystinuria caused by cystathionine beta synthase (CBS) deficiency is most often diagnosed in childhood and has a variable expressivity. The most frequent abnormalities include intellectual disability, ectopia lentis, myopia, skeletal abnormalities or thromboembolism. To report a case of homocystinuria unraveled by[…] [ncbi.nlm.nih.gov] Diffuse Palmoplantar Keratoderma Four members of a family, in which 8 suffered from diffuse palmoplantar keratoderma associated with an uncommon form of acrocyanosis, are reported. [ncbi.nlm.nih.gov] […] syndrome Acquired acanthosis nigricans Acquired perforating pseudoxanthoma elasticum Acquired pseudoxanthoma elasticum Acral Darier's disease Acral peeling skin syndrome Acrocyanosis [icdlist.com] […] fluorouracil, bleomycin, hydroxyurea, practolol and doxorubicin. 5 Systemic diseases like myxedema, diabetes mellitus, chronic lymphedema and other circulatory disorders such as acrocyanosis [jemds.com]
