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3,531 Possible Causes for activation, biosynthetic, of, process, prostaglandin

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  • Acute Inflammation

    OBJECTIVE: The cognitive neuropsychological model of depression proposes that negative biases in the processing of emotionally salient information have a central role in the[ncbi.nlm.nih.gov] Previous studies on EGC pathophysiology have specifically focused on mucosal glia activation and its contribution to mucosal inflammatory processes observed in the gut of[ncbi.nlm.nih.gov] KEYWORDS: 15d-PGJ(2); Free radicals; Lipocalin-type prostaglandin D synthase; Lipopolysaccharide; NADPH oxidase 2; NF-κB; Nrf2; Peroxiredoxin; Polyphenols; Prostaglandin;[ncbi.nlm.nih.gov] […] transcellular biosynthetic mechanism; neutrophillic stimulation of platelets What are some actions of PAF?[studystack.com] […] potentiated permeability and chemotactic effects of other mediators · Thromboxane - vasoconstrictor, platelet aggregation Lipoxins are derived from AA via transcellular biosynthetic[pathologyexpert.com]

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  • Dementia

    (9%), or without a dominant pathologic process recognized (55%).[ncbi.nlm.nih.gov] Alkayed , Role of soluble epoxide hydrolase in age-related vascular cognitive decline , Prostaglandins & Other Lipid Mediators , 113-115 , (30) , (2014) . Stephen W.[doi.org] In the 1950s, the chemical identification of the carbohydrate structure of surface antigens led to the understanding of biosynthetic pathways.[ncbi.nlm.nih.gov] Background: Nursing home (NH) residents with dementia experience a reduced quality of life (QoL), in part, due to a dependence in performing activities of daily living (ADL[ncbi.nlm.nih.gov] We extract higher-level activity patterns which are then used to detect any change in patients' routines.[ncbi.nlm.nih.gov]

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  • Porphyria

    Normally, the body makes heme in a multi-step process. Porphyrins are made during several steps of this process.[nlm.nih.gov] […] involves withdrawal of offending drugs, treatment of symptoms with appropriate medications, and attempts to reverse factors that increase aminolevulinic acid synthetase activity[doi.org] […] example, oxygen binding and transport, mixed-function oxidation in the cytochrome P-450 pathway, activation and decomposition of hydrogen peroxide, oxidation of tryptophan and prostaglandins[emedicine.medscape.com] Abstract Porphyrias are inherited metabolic disorders that involve alterations in enzymes utilized in the heme biosynthetic pathway.[ncbi.nlm.nih.gov] PURPOSE: The acute porphyrias are a group of rare metabolic disorders of the heme biosynthetic pathway.[ncbi.nlm.nih.gov]

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  • Novobiocin

    Of the three cell lines tested, only the early KG-1a expressed N-cadherin, a member of Ca(2 )-dependent adhesion molecules involved in embryonic differentiation processes.[ncbi.nlm.nih.gov] Sodium-independent organic anion transmembrane transporter activity Specific Function Mediates the Na( )-independent transport of organic anions such as taurocholate, the prostaglandins[drugbank.ca] Hypothetical biosynthetic pathway of novobiocin. Roman numerals refer to the putative assignments of genes identified in the biosynthetic reactions (see Table 1 ).[doi.org] Novobiocin is an orally active antibiotic that inhibits DNA gyrase by binding the ATP-binding site in the ATPase subunit.[ncbi.nlm.nih.gov] The processing and activation of caspases 7 and 8 and the subsequent cleavage of PARP by 6e suggest stimulation of the extrinsic apoptosis pathway.[ncbi.nlm.nih.gov]

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  • Hyporeninemic Hypoaldosteronism

    Therefore, a process of intrinsic hyperactive distal sodium reabsorption, probably affected by aldosterone-independent sodium transport into erythrocytes, appears to be important[ncbi.nlm.nih.gov] It is of interest that the serum erythropoietin activity in this case was increased while plasma renin activity was markedly depressed.[ncbi.nlm.nih.gov] Abstract A deficiency in renal prostaglandin synthesis has been proposed as the cause of the syndrome of hyporeninemic hypoaldosteronism.[ncbi.nlm.nih.gov] In children, adrenal biosynthetic enzyme deficiencies may produce aldosterone deficiency.[questdiagnostics.com] […] diagnosis and treatment of specific diseases, disorders, and complications and incorporates the basic science practicing physicians need to evaluate and manage the disease process[books.google.com]

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  • Curcumin

    , Zhanjiang 524088, China. [email protected] 2 Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, Guangzhou 510640, China.[ncbi.nlm.nih.gov] Both transferrin receptor 1 and activated IRP, indicators of iron depletion, increased in response to curcumin.[ncbi.nlm.nih.gov] Prostaglandins Leukot Med. 22: 357-360. PMID: 3460103 2. Flynn, D.L., et al. 1986. Prostaglandins Leukot Med. 24: 195-198. PMID: 3467378 3. Chan, M.M. 1995. Biochem.[scbt.com] Alzheimer's disease; IL, interleukin; pJNK, phospho-JNK, c-Jun NH 2 -terminal kinase; JNK, c-Jun NH 2 -terminal kinase; iNOS, inducible nitric-oxide synthase; 8-iso-PGE 2α , 8-iso-prostaglandin[doi.org] Author information 1 Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand-247667, India. 2 Nanobiotechnology Laboratory[ncbi.nlm.nih.gov]

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  • Licofelone

    Moreover, licofelone induced the cleavage of the full-length p21(Bax) into p18(Bax), a more potent inducer of the apoptotic process than the uncleaved form.[ncbi.nlm.nih.gov] The main limitation in using NSAIDs consists in their side-effects, including gastrointestinal ulcerogenic activity and bronchospasm.[ncbi.nlm.nih.gov] ML3000; 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid], currently undergoing phase III trials for osteoarthritis, inhibits the prostaglandin[ncbi.nlm.nih.gov] Abstract 5-Lipoxygenase/cyclooxygenase inhibitors, possessing anti-inflammatory action and gastric safety due to cyclooxygenase-2 and 5-lipoxygenase inhibition and antiplatelet activity[ncbi.nlm.nih.gov] Both the gastric and renal toxicities induced by traditional NSAIDs and selective COX-2 inhibitors seem to be related to inhibition of prostaglandin, but not leukotriene,[ncbi.nlm.nih.gov]

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  • Hypoaldosteronism

    […] glomerular filtration rate of 33.9 /- 9.03 ml/min who had hyporeninaemic hypoaldosteronism to evaluate the influence of these prostaglandins on the appearance of this latter process[ncbi.nlm.nih.gov] Seven of 11 patients had prostaglandin E2 excretion rates lower than either control groups.[ncbi.nlm.nih.gov] Metabolic studies as the short-term response of serum Na to high dose FF may not be helpful in differentiating aldosterone biosynthetic defects from end-organ resistance to[ncbi.nlm.nih.gov] The results were consistent with the abnormalities seen in selective hypoaldosteronism with low renin activity.[ncbi.nlm.nih.gov] Two forms of this disorder: CMO type I reflects a biosynthetic defect at the level of the 18 hydroxylation of corticosterone.[enotes.tripod.com]

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  • Polyphenol

    Raw and processed breadfruit had higher hydrolysis curves than raw and processed beans with the amylolysis level in raw breadfruit close to that of white bread.[ncbi.nlm.nih.gov] How do they express their biological activity? Are they really valuable for disease prevention? Can they be used to develop new pharmaceutical drugs?[ncbi.nlm.nih.gov] Abstract In the present study, we examined whether particular urinary oxylipins (isoprostanes (IsoPs), leukotrienes (LTs), prostaglandins (PGs), and thromboxanes (TXs)) in[ncbi.nlm.nih.gov] […] review highlights recently unveiled biosynthetic mechanisms to generate highly diverse and complex molecules.[ncbi.nlm.nih.gov] ) radiation) and found the activity to be unaffected or slightly reduced.[doi.org]

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  • Scutellaria Baicalensis

    Abstract In this study, we sought to increase the anti-inflammatory activity of Scutellaria baicalensis extracts using a nanoencapsulation process.[ncbi.nlm.nih.gov] The pure compounds were evaluated for anti-influenza activities against A/WSN/33 (H1N1) virus in MDCK cells, cytotoxic activities against HepG2, SW480 and MCF7 human cancer[ncbi.nlm.nih.gov] […] activity on head and neck squamous cell carcinoma (HNSCC) in vitro and in vivo and to investigate its effect on cyclooxygenase-2 (COX-2), which converts arachidonic acid to prostaglandin[ncbi.nlm.nih.gov] A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis .[sci-news.com] Neutrophil density and IL-6 and TNF-α mRNA levels were determined in the pouch membrane, and the leukocyte count and IL-6, prostaglandin E 2 (PGE 2 ) and prostaglandin D 2[arthritis-research.com]

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